(Q39211305)

10 September 2017

Phenotypic profiling of structural cardiotoxins in vitro reveals dependency on multiple mechanisms of toxicity (English)

1 reference

10 September 2017

Amy Pointon

1

1 reference

10 September 2017

Najah Abi-Gerges

series ordinal

2

1 reference

10 September 2017

Michael J Cross

series ordinal

3

1 reference

10 September 2017

James E Sidaway

series ordinal

4

1 reference

10 September 2017

12 January 2013

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10 September 2017

Toxicological Sciences

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10 September 2017

132

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10 September 2017

2

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10 September 2017

317-326

1 reference

Dynamic monitoring of beating periodicity of stem cell-derived cardiomyocytes as a predictive tool for preclinical safety assessment

10 September 2017

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Dog left ventricular midmyocardial myocytes for assessment of drug-induced delayed repolarization: short-term variability and proarrhythmic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Cardiotoxicity of anticancer drugs: the need for cardio-oncology and cardio-oncological prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Cardiac excitation-contraction coupling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Adriamycin-induced oxidative mitochondrial cardiotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

In vitro electrophysiological drug testing using human embryonic stem cell derived cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Cardiac sodium-calcium exchanger: a double-edged sword

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Roles of mitochondria in health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

The significance of mitochondrial toxicity testing in drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Cardiotoxicity of kinase inhibitors: the prediction and translation of preclinical models to clinical outcomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Glutathione peroxidase 1-deficient mice are more susceptible to doxorubicin-induced cardiotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Estimating the risk of drug-induced proarrhythmia using human induced pluripotent stem cell-derived cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Cardionomics: a new integrative approach for screening cardiotoxicity of drug candidates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Validation of an in vitro contractility assay using canine ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

The cardiotoxicity and myocyte damage caused by small molecule anticancer tyrosine kinase inhibitors is correlated with lack of target specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Mitochondrial membrane dynamics, cristae remodelling and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Morphological, biochemical, and electrophysiological characterization of a clonal cell (H9c2) line from rat heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Cell death assays for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Cardiotoxicity of the cancer therapeutic agent imatinib mesylate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Sunitinib-induced cardiotoxicity is mediated by off-target inhibition of AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Properties of a clonal muscle cell line from rat heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Stem cells for drug screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

The use of receiver operating characteristic curves in biomedical informatics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

How can we improve our understanding of cardiovascular safety liabilities to develop safer medicines?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Mitochondrial damage as death inducer in heart-derived H9c2 cells: more than one way for an early demise

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Calcium-sensing receptors regulate cardiomyocyte Ca2+ signaling via the sarcoplasmic reticulum-mitochondrion interface during hypoxia/reoxygenation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Contribution of reverse-mode sodium-calcium exchange to contractions in failing human left ventricular myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Cardiotoxicity associated with targeting kinase pathways in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

ER stress in cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Drug-induced cardiovascular disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

An introduction to QT interval prolongation and non-clinical approaches to assessing and reducing risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Altered cytosolic Ca2+ dynamics in cultured Guinea pig cardiomyocytes as an in vitro model to identify potential cardiotoxicants

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Apoptosis of ventricular myocytes: a means to an end.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Embryonic stem cell-derived cardiac, neuronal and pancreatic cells as model systems to study toxicological effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Usefulness of NT-pro-BNP and echocardiography in the diagnosis of subclinical clozapine-related cardiotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Cardiotoxicity of cytotoxic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

The impact of assay technology as applied to safety assessment in reducing compound attrition in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Multiple interference of anthracyclines with mitochondrial creatine kinases: preferential damage of the cardiac isoenzyme and its implications for drug cardiotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

A framework to assess the translation of safety pharmacology data to humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Value of non-clinical cardiac repolarization assays in supporting the discovery and development of safer medicines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Adriamycin-induced interference with cardiac mitochondrial calcium homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Effect of the multitargeted tyrosine kinase inhibitors imatinib, dasatinib, sunitinib, and sorafenib on mitochondrial function in isolated rat heart mitochondria and H9c2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Cellular imaging predictions of clinical drug-induced liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

Cardiomyocytes derived from human pluripotent stem cells for drug screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFT005

21 January 2018

Identifiers

DOI

10.1093/TOXSCI/KFT005

1 reference

10 September 2017

1 reference