(Q39229674)

10 September 2017

Role of drug efflux and uptake transporters in atazanavir intestinal permeability and drug-drug interactions (English)

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10 September 2017

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4

Sharon L Walmsley

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10 September 2017

Olena Kis

1

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10 September 2017

Jason A Zastre

series ordinal

2

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10 September 2017

Md Tozammel Hoque

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3

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10 September 2017

Reina Bendayan

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5

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10 September 2017

7 December 2012

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10 September 2017

Pharmaceutical Research

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10 September 2017

30

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10 September 2017

1050-1064

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10 September 2017

4

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Atazanavir/ritonavir: a review of its use in HIV therapy

10 September 2017

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Effect of variations in the amounts of P-glycoprotein (ABCB1), BCRP (ABCG2) and CYP3A4 along the human small intestine on PBPK models for predicting intestinal first pass.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

The complexities of antiretroviral drug-drug interactions: role of ABC and SLC transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

The ABCs of drug transport in intestine and liver: efflux proteins limiting drug absorption and bioavailability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Antiretrovirals, part 1: overview, history, and focus on protease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Comparison of the inhibitory activity of anti-HIV drugs on P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Atazanavir: effects on P-glycoprotein transport and CYP3A metabolism in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Induction of P-glycoprotein expression by HIV protease inhibitors in cell culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Comparison of the induction of P-glycoprotein activity by nucleotide, nucleoside, and non-nucleoside reverse transcriptase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Protease inhibitors atazanavir, lopinavir and ritonavir are potent blockers, but poor substrates, of ABC transporters in a broad panel of ABC transporter-overexpressing cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Assessment of active transport of HIV protease inhibitors in various cell lines and the in vitro blood--brain barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Modulation of the intracellular accumulation of saquinavir in peripheral blood mononuclear cells by inhibitors of MRP1, MRP2, P-gp and BCRP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Multidrug resistance protein 2 (MRP2) transports HIV protease inhibitors, and transport can be enhanced by other drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Inhibition of MRP1/ABCC1, MRP2/ABCC2, and MRP3/ABCC3 by nucleoside, nucleotide, and non-nucleoside reverse transcriptase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Modulation of human BCRP (ABCG2) activity by anti-HIV drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

HIV protease inhibitors are inhibitors but not substrates of the human breast cancer resistance protein (BCRP/ABCG2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Organic anion-transporting polypeptide (OATP) transporter family and drug disposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Pharmacogenetics of intestinal absorption.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Interaction of HIV protease inhibitors with OATP1B1, 1B3, and 2B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

pH dependence of organic anion-transporting polypeptide 2B1 in Caco-2 cells: potential role in antiretroviral drug oral bioavailability and drug-drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

P-glycoprotein, multidrug resistance-associated proteins and human organic anion transporting polypeptide influence the intracellular accumulation of atazanavir

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Determination of drug permeability and prediction of drug absorption in Caco-2 monolayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Targeted disruption of peptide transporter Pept1 gene in mice significantly reduces dipeptide absorption in intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Significance and regional dependency of peptide transporter (PEPT) 1 in the intestinal permeability of glycylsarcosine: in situ single-pass perfusion studies in wild-type and Pept1 knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Quantitative evaluation of the function of small intestinal P-glycoprotein: comparative studies between in situ and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Segmental dependent transport of low permeability compounds along the small intestine due to P-glycoprotein: the role of efflux transport in the oral absorption of BCS class III drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Closing the gaps: a full scan of the intestinal expression of p-glycoprotein, breast cancer resistance protein, and multidrug resistance-associated protein 2 in male and female rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Up-regulation of P-glycoprotein by HIV protease inhibitors in a human brain microvessel endothelial cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Comparison of ABC transporter modulation by atazanavir in lymphocytes and human brain endothelial cells: ABC transporters are involved in the atazanavir-limited passage across an in vitro human model of the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Variability in mRNA expression of ABC- and SLC-transporters in human intestinal cells: comparison between human segments and Caco-2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

A combined cell based approach to identify P-glycoprotein substrates and inhibitors in a single assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Uptake transporters of the human OATP family: molecular characteristics, substrates, their role in drug-drug interactions, and functional consequences of polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Intestinal drug transporter expression and the impact of grapefruit juice in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Predominant contribution of organic anion transporting polypeptide OATP-B (OATP2B1) to apical uptake of estrone-3-sulfate by human intestinal Caco-2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Antiretrovirals, Part II: focus on non-protease inhibitor antiretrovirals (NRTIs, NNRTIs, and fusion inhibitors).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Effects of human immunodeficiency virus protease inhibitors on the intestinal absorption of tenofovir disoproxil fumarate in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Tenofovir disoproxil fumarate: clinical pharmacology and pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Analysis of CYP3A4-HIV-1 protease drugs interactions by computational methods for Highly Active Antiretroviral Therapy in HIV/AIDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Atazanavir metabolism according to CYP3A5 status: an in vitro-in vivo assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

A population pharmacokinetic-pharmacogenetic analysis of atazanavir

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Boosting of HIV Protease Inhibitors by Ritonavir in the Intestine: The Relative Role of Cytochrome P450 and P-Glycoprotein Inhibition Based on Caco-2 Monolayers versus In Situ Intestinal Perfusion in Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0942-Y

Regional distribution of solute carrier mRNA expression along the human intestinal tract

21 January 2018

1 reference

12 December 2020

Influence of tenofovir, nevirapine and efavirenz on ritonavir-boosted atazanavir pharmacokinetics in HIV-infected patients

1 reference

12 December 2020

Correlation of gene expression of ten drug efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial Caco-2 cell monolayers.

1 reference

12 December 2020

Site of drug absorption after oral administration: assessment of membrane permeability and luminal concentration of drugs in each segment of gastrointestinal tract

1 reference

12 December 2020

Inhibition of human liver microsomal cytochrome P450 activities by adefovir and tenofovir

1 reference

12 December 2020

Predicting human intestinal permeability using single-pass intestinal perfusion in rat.

1 reference

12 December 2020

10.1007/S11095-012-0942-Y

Identifiers

DOI

1 reference

10 September 2017

1 reference