(Q39264494)

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Overexpression of peroxisome proliferator-activated receptor α in pancreatic β-cells improves glucose tolerance in diet-induced obese mice

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scholarly article

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Europe PubMed Central

10 September 2017

Overexpression of peroxisome proliferator-activated receptor α in pancreatic β-cells improves glucose tolerance in diet-induced obese mice (English)

1 reference

Europe PubMed Central

10 September 2017

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author name string

K-Lynn N Hogh

1

1 reference

Europe PubMed Central

10 September 2017

Christopher E Uy

2

1 reference

Europe PubMed Central

10 September 2017

Ali Asadi

3

1 reference

Europe PubMed Central

10 September 2017

Robert K Baker

4

1 reference

Europe PubMed Central

10 September 2017

Michael J Riedel

5

1 reference

Europe PubMed Central

10 September 2017

Sarah L Gray

6

1 reference

Europe PubMed Central

10 September 2017

publication date

5 October 2012

1 reference

Europe PubMed Central

10 September 2017

Experimental Physiology

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Europe PubMed Central

10 September 2017

98

1 reference

Europe PubMed Central

10 September 2017

2

1 reference

Europe PubMed Central

10 September 2017

564-575

1 reference

Europe PubMed Central

10 September 2017

Peroxisome proliferator-activated receptor (PPAR)-alpha agonism prevents the onset of type 2 diabetes in Zucker diabetic fatty rats: A comparison with PPAR gamma agonism.

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Pancreatic islet response to hyperglycemia is dependent on peroxisome proliferator-activated receptor alpha (PPARalpha).

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Lipid oversupply, selective insulin resistance, and lipotoxicity: molecular mechanisms

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

The role of insulin receptor substrate 2 in hypothalamic and beta cell function.

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Advanced transfection with Lipofectamine 2000 reagent: primary neurons, siRNA, and high-throughput applications

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Peroxisome-generated hydrogen peroxide as important mediator of lipotoxicity in insulin-producing cells

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Peroxisome proliferator-activated receptor alpha (PPARalpha) protects against oleate-induced INS-1E beta cell dysfunction by preserving carbohydrate metabolism

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

In vivo expression of HGF/NK1 and GLP-1 From dsAAV vectors enhances pancreatic ß-cell proliferation and improves pathology in the db/db mouse model of diabetes

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Role of metabolically generated reactive oxygen species for lipotoxicity in pancreatic β-cells

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Lipid-induced pancreatic β-cell dysfunction: focus on in vivo studies

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Effects of palmitate on ER and cytosolic Ca2+ homeostasis in beta-cells

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Peroxisome proliferator-activated receptor alpha-retinoid X receptor agonists induce beta-cell protection against palmitate toxicity

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Acute (24 h) activation of peroxisome proliferator-activated receptor-alpha (PPARalpha) reverses high-fat feeding-induced insulin hypersecretion in vivo and in perifused pancreatic islets

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Disruption of hepatic leptin signaling protects mice from age- and diet-related glucose intolerance

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Peroxisome proliferator-activated receptor (PPAR)-alpha activation prevents diabetes in OLETF rats: comparison with PPAR-gamma activation

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Peroxisome proliferator-activated receptor alpha improves pancreatic adaptation to insulin resistance in obese mice and reduces lipotoxicity in human islets.

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Metabolic mechanisms of failure of intraportally transplanted pancreatic beta-cells in rats: role of lipotoxicity and prevention by leptin.

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Fatty acid signaling in the beta-cell and insulin secretion

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Islet beta cell failure in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Peroxisome proliferator-activated receptor alpha (PPARalpha) potentiates, whereas PPARgamma attenuates, glucose-stimulated insulin secretion in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

DsAAV8-mediated expression of glucagon-like peptide-1 in pancreatic beta-cells ameliorates streptozotocin-induced diabetes

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Diabetes and obesity: the twin epidemics

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Fibrates and future PPARalpha agonists in the treatment of cardiovascular disease

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Peroxisome proliferator-activated receptor-alpha activation during pregnancy attenuates glucose-stimulated insulin hypersecretion in vivo by increasing insulin sensitivity, without impairing pregnancy-induced increases in beta-cell glucose sensing a

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Lipotoxic diseases

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Lipid accumulation in non-adipose tissue and lipotoxicity

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome--an allostatic perspective

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Widespread and stable pancreatic gene transfer by adeno-associated virus vectors via different routes.

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Oral taurine but not N-acetylcysteine ameliorates NEFA-induced impairment in insulin sensitivity and beta cell function in obese and overweight, non-diabetic men.

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

The effect of chronic exposure to fatty acids on gene expression in clonal insulin-producing cells: studies using high density oligonucleotide microarray.

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Peroxisome proliferator-activated receptor-alpha modulates insulin gene transcription factors and inflammation in adipose tissues in mice

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

Peroxisome Proliferator-activated Receptor α Activators Improve Insulin Sensitivity and Reduce Adiposity

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2012.068734

21 January 2018

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10.1113/EXPPHYSIOL.2012.068734

1 reference

Europe PubMed Central

10 September 2017

release_ef5zfhkxcfhfxc7ji5i7a3bxpy

1 reference

https://api.fatcat.wiki/v0/release/ef5zfhkxcfhfxc7ji5i7a3bxpy

24 November 2022

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Europe PubMed Central

10 September 2017

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