(Q39289136)

10 September 2017

title

Loss of miR-101 expression promotes Wnt/β-catenin signalling pathway activation and malignancy in colon cancer cells (English)

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10 September 2017

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5

Annamaria Sgromo

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Antonio Strillacci

Antonio Strillacci

1

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Enzo Spisni

Enzo Spisni

11

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Fernando Rizzello

Fernando Rizzello

9

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Massimo Campieri

Massimo Campieri

10

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author name string

Maria Chiara Valerii

2

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Pasquale Sansone

3

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Cinzia Caggiano

4

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Laura Vittori

6

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Michelangelo Fiorentino

7

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Gilberto Poggioli

8

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10 September 2017

publication date

28 November 2012

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10 September 2017

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volume

229

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issue

3

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10 September 2017

page(s)

379-389

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Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

10 September 2017

cites work

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Interstitial cell cyclooxygenase-2 expression is associated with increased angiogenesis in human sporadic colorectal adenomas.

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RNA interference as a key to knockdown overexpressed cyclooxygenase-2 gene in tumour cells

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Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial

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RNAi-based strategies for cyclooxygenase-2 inhibition in cancer.

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A microRNA expression signature of human solid tumors defines cancer gene targets

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microRNAs as oncogenes and tumor suppressors

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MicroRNA expression profiling of human metastatic cancers identifies cancer gene targets

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21 January 2018

miRNAs in human cancer

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Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

21 January 2018

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Lack of microRNA-101 causes E-cadherin functional deregulation through EZH2 up-regulation in intestinal gastric cancer

21 January 2018

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MicroRNA-101 is down-regulated in gastric cancer and involved in cell migration and invasion

21 January 2018

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miR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesis

21 January 2018

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MicroRNA-101 exerts tumor-suppressive functions in non-small cell lung cancer through directly targeting enhancer of zeste homolog 2.

21 January 2018

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MicroRNA-101 inhibits growth of epithelial ovarian cancer by relieving chromatin-mediated transcriptional repression of p21(waf¹/cip¹).

21 January 2018

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miR-101 DNA copy loss is a prominent subtype specific event in lung cancer

21 January 2018

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MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity

21 January 2018

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Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation

21 January 2018

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Tumour-suppressor microRNAs let-7 and mir-101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN-amplified neuroblastoma

21 January 2018

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MiR-101 downregulation is involved in cyclooxygenase-2 overexpression in human colon cancer cells.

21 January 2018

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Transcriptional activation of the beta-catenin gene at the invasion front of colorectal liver metastases.

21 January 2018

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Invasion and metastasis in colorectal cancer: epithelial-mesenchymal transition, mesenchymal-epithelial transition, stem cells and beta-catenin

21 January 2018

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The basics of epithelial-mesenchymal transition

21 January 2018

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Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

21 January 2018

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Autoregulation of E-cadherin expression by cadherin-cadherin interactions: the roles of beta-catenin signaling, Slug, and MAPK

21 January 2018

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E-cadherin, beta-catenin, and ZEB1 in malignant progression of cancer

21 January 2018

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Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

21 January 2018

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WNT-conditioned media differentially affect the proliferation and differentiation of cord blood-derived CD133+ cells in vitro

21 January 2018

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Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway

21 January 2018

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Identification and expansion of human colon-cancer-initiating cells

21 January 2018

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Hypoxia generates a more invasive phenotype of tumour cells: an in vivo experimental setup based on the chorioallantoic membrane.

21 January 2018

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Cyclooxygenase-2/carbonic anhydrase-IX up-regulation promotes invasive potential and hypoxia survival in colorectal cancer cells

21 January 2018

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Malignant progression of invasive tumour cells seen in hypoxia present an accumulation of beta-catenin in the nucleus at the tumour front.

21 January 2018

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Activation of beta-catenin by hypoxia in hepatocellular carcinoma contributes to enhanced metastatic potential and poor prognosis.

21 January 2018

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Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia

21 January 2018

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Cyclooxygenase-2 increases hypoxia-inducible factor-1 and vascular endothelial growth factor to promote angiogenesis in gastric carcinoma

21 January 2018

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NCM460, a normal human colon mucosal epithelial cell line

21 January 2018

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Selective cyclooxygenase-2 silencing mediated by engineered E. coli and RNA interference induces anti-tumour effects in human colon cancer cells

21 January 2018

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Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment

21 January 2018

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Subcellular localization of beta-catenin is regulated by cell density

21 January 2018

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Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

21 January 2018

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CD44 isoforms are heterogeneously expressed in breast cancer and correlate with tumor subtypes and cancer stem cell markers

21 January 2018

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CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression

21 January 2018

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MicroRNA-101 (miR-101) post-transcriptionally regulates the expression of EP4 receptor in colon cancers

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PATH.4097

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10 September 2017

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