(Q39289989)

10 September 2017

title

Overexpression of CHOP alone and in combination with chaperones is effective in improving antibody production in mammalian cells (English)

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10 September 2017

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Daisuke Nishimiya

1

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10 September 2017

Takashi Mano

2

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10 September 2017

Kenji Miyadai

3

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10 September 2017

Hiroko Yoshida

4

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10 September 2017

Tohru Takahashi

5

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10 September 2017

language of work or name

English

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publication date

29 August 2012

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Applied Microbiology and Biotechnology

10 September 2017

published in

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10 September 2017

volume

97

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10 September 2017

issue

6

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10 September 2017

page(s)

2531-2539

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The cold-shock response in cultured mammalian cells: harnessing the response for the improvement of recombinant protein production.

10 September 2017

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Mammalian cell factories for efficient and stable protein expression

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The use of UCOE vectors in combination with a preadapted serum free, suspension cell line allows for rapid production of large quantities of protein

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Effect of increased expression of protein disulfide isomerase and heavy chain binding protein on antibody secretion in a recombinant CHO cell line

21 January 2018

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Engineering responsiveness to cell culture stresses: growth arrest and DNA damage gene 153 (GADD153) and the unfolded protein response (UPR) in NS0 myeloma cells

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Engineering mammalian cell factories for improved recombinant monoclonal antibody production: lessons from nature?

21 January 2018

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Functional proteomic analysis of GS-NS0 murine myeloma cell lines with varying recombinant monoclonal antibody production rate

21 January 2018

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An unfolded CH1 domain controls the assembly and secretion of IgG antibodies.

21 January 2018

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21 January 2018

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Genome-wide prediction of matrix attachment regions that increase gene expression in mammalian cells

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Sustained transgene expression using MAR elements

21 January 2018

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Constraints on the transport and glycosylation of recombinant IFN-gamma in Chinese hamster ovary and insect cells.

21 January 2018

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Maximizing productivity of CHO cell-based fed-batch culture using chemically defined media conditions and typical manufacturing equipment

21 January 2018

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Post-translational modifications of recombinant proteins: significance for biopharmaceuticals

21 January 2018

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Regulated release of ERdj3 from unfolded proteins by BiP

21 January 2018

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21 January 2018

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CHO cells in biotechnology for production of recombinant proteins: current state and further potential

21 January 2018

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Protein folding and quality control in the endoplasmic reticulum

21 January 2018

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21 January 2018

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21 January 2018

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A comparative study of different vector designs for the mammalian expression of recombinant IgG antibodies

21 January 2018

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Comparative metabolite analysis to understand lactate metabolism shift in Chinese hamster ovary cell culture process

21 January 2018

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Manipulation of oxidative protein folding and PDI redox state in mammalian cells

21 January 2018

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Expression of the transcription factor GADD153 is an indicator of apoptosis for recombinant chinese hamster ovary (CHO) cells

21 January 2018

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Identification of antibody-interacting proteins that contribute to the production of recombinant antibody in mammalian cells

21 January 2018

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Improved production of recombinant human antithrombin III in Chinese hamster ovary cells by ATF4 overexpression.

21 January 2018

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Cell engineering and cultivation of chinese hamster ovary (CHO) cells.

21 January 2018

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Roles of CHOP/GADD153 in endoplasmic reticulum stress

21 January 2018

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Rapid whole monoclonal antibody analysis by mass spectrometry: An ultra scale-down study of the effect of harvesting by centrifugation on the post-translational modification profile.

21 January 2018

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21 January 2018

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21 January 2018

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Increasing the secretory capacity of Saccharomyces cerevisiae for production of single-chain antibody fragments

21 January 2018

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Comparative proteomic analysis of GS-NS0 murine myeloma cell lines with varying recombinant monoclonal antibody production rate.

21 January 2018

1 reference

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ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER

21 January 2018

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Effects of inactivation and constitutive expression of the unfolded- protein response pathway on protein production in the yeast Saccharomyces cerevisiae

21 January 2018

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Identification of novel stress-induced genes downstream of chop

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-012-4365-9

Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153).

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00253-012-4365-9

Glycosylation of therapeutic proteins in different production systems.

21 January 2018

1 reference

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EST sequencing for gene discovery in Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-012-4365-9

Production of recombinant protein therapeutics in cultivated mammalian cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00253-012-4365-9

Sequential interaction of the chaperones BiP and GRP94 with immunoglobulin chains in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-012-4365-9

10.1007/S00253-012-4365-9

21 January 2018

Identifiers

DOI

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10 September 2017

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