(Q39293643)

10 September 2017

title

CCR5 interactions with the variable 3 loop of gp120. (English)

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10 September 2017

Kelby B Napier

1

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10 September 2017

Zi-xuan Wang

series ordinal

2

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10 September 2017

Stephen C Peiper

series ordinal

3

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10 September 2017

John O Trent

series ordinal

4

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10 September 2017

publication date

24 May 2006

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Journal of Molecular Modeling

10 September 2017

published in

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10 September 2017

volume

13

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10 September 2017

issue

1

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10 September 2017

page(s)

29-41

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Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s

10 September 2017

cites work

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12 December 2020

Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes

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12 December 2020

The complete Consensus V3 loop peptide of the envelope protein gp120 of HIV-1 shows pronounced helical character in solution

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12 December 2020

The region of the envelope gene of human immunodeficiency virus type 1 responsible for determination of cell tropism

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12 December 2020

Definition of general topological equivalence in protein structures. A procedure involving comparison of properties and relationships through simulated annealing and dynamic programming

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12 December 2020

CCR5 coreceptor utilization involves a highly conserved arginine residue of HIV type 1 gp120.

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12 December 2020

Molecular cloning and functional expression of a new human CC-chemokine receptor gene

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12 December 2020

Amino-terminal substitutions in the CCR5 coreceptor impair gp120 binding and human immunodeficiency virus type 1 entry

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12 December 2020

Two distinct CCR5 domains can mediate coreceptor usage by human immunodeficiency virus type 1.

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12 December 2020

A critical site in the core of the CCR5 chemokine receptor required for binding and infectivity of human immunodeficiency virus type 1.

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12 December 2020

CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.

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12 December 2020

A tyrosine-rich region in the N terminus of CCR5 is important for human immunodeficiency virus type 1 entry and mediates an association between gp120 and CCR5

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12 December 2020

CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1

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12 December 2020

Increased viral burden and cytopathicity correlate temporally with CD4+ T-lymphocyte decline and clinical progression in human immunodeficiency virus type 1-infected individuals.

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12 December 2020

Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1.

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12 December 2020

Sensitivity to inhibition by beta-chemokines correlates with biological phenotypes of primary HIV-1 isolates

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12 December 2020

Specific inhibition of HIV-1 coreceptor activity by synthetic peptides corresponding to the predicted extracellular loops of CCR5.

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12 December 2020

Molecular surface recognition: determination of geometric fit between proteins and their ligands by correlation techniques

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12 December 2020

CCR5 HIV-1 coreceptor activity. Role of cooperativity between residues in N-terminal extracellular and intracellular domains

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12 December 2020

Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells

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12 December 2020

A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5

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12 December 2020

Structural and functional characterization of human CXCR4 as a chemokine receptor and HIV-1 co-receptor by mutagenesis and molecular modeling studies

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12 December 2020

Human immunodeficiency virus type 1 gp120 envelope glycoprotein regions important for association with the gp41 transmembrane glycoprotein

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12 December 2020

A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity

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12 December 2020

Identification of ENV determinants in V3 that influence the molecular anatomy of CCR5 utilization

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12 December 2020

Dimeric association and segmental variability in the structure of human CD4

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12 December 2020

Extracellular cysteines of CCR5 are required for chemokine binding, but dispensable for HIV-1 coreceptor activity

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12 December 2020

Prediction of structure and function of G protein-coupled receptors

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12 December 2020

Differential inhibition of human immunodeficiency virus type 1 fusion, gp120 binding, and CC-chemokine activity by monoclonal antibodies to CCR5

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12 December 2020

Molecular mimicry of human cytokine and cytokine response pathway genes by KSHV.

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12 December 2020

Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages

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12 December 2020

Hypervariable region 3 residues of HIV type 1 gp120 involved in CCR5 coreceptor utilization: therapeutic and prophylactic implications

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12 December 2020

Crystal structure of rhodopsin: A G protein-coupled receptor

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12 December 2020

A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding

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12 December 2020

Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population

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12 December 2020

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

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12 December 2020

Multiple extracellular elements of CCR5 and HIV-1 entry: dissociation from response to chemokines

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12 December 2020

Molecular dynamics simulations on SDF-1alpha: binding with CXCR4 receptor

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12 December 2020

Molecular anatomy of CCR5 engagement by physiologic and viral chemokines and HIV-1 envelope glycoproteins: differences in primary structural requirements for RANTES, MIP-1 alpha, and vMIP-II Binding

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12 December 2020

Restricted variable residues in the C-terminal segment of HIV-1 V3 loop regulate the molecular anatomy of CCR5 utilization

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12 December 2020

Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function

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12 December 2020

The differential sensitivity of human and rhesus macaque CCR5 to small-molecule inhibitors of human immunodeficiency virus type 1 entry is explained by a single amino acid difference and suggests a mechanism of action for these inhibitors

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12 December 2020

Mapping the determinants of the CCR5 amino-terminal sulfopeptide interaction with soluble human immunodeficiency virus type 1 gp120-CD4 complexes

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12 December 2020

Selective employment of chemokine receptors as human immunodeficiency virus type 1 coreceptors determined by individual amino acids within the envelope V3 loop

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12 December 2020

Molecular modeling on human CCR5 receptors and complex with CD4 antigens and HIV-1 envelope glycoprotein gp120.

1 reference

12 December 2020

Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection

1 reference

12 December 2020

CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5.

1 reference

12 December 2020

Structure modeling of the chemokine receptor CCR5: implications for ligand binding and selectivity

1 reference

12 December 2020

Identification of a major co-receptor for primary isolates of HIV-1

1 reference

12 December 2020

A tyrosine-sulfated peptide based on the N terminus of CCR5 interacts with a CD4-enhanced epitope of the HIV-1 gp120 envelope glycoprotein and inhibits HIV-1 entry

1 reference

12 December 2020

Binding of 2-aryl-4-(piperidin-1-yl)butanamines and 1,3,4-trisubstituted pyrrolidines to human CCR5: a molecular modeling-guided mutagenesis study of the binding pocket

1 reference

12 December 2020

Regions in beta-chemokine receptors CCR5 and CCR2b that determine HIV-1 cofactor specificity

1 reference

12 December 2020

Lipid bilayer simulations of CXCR4 with inverse agonists and weak partial agonists

1 reference

12 December 2020

Analysis of the mechanism by which the small-molecule CCR5 antagonists SCH-351125 and SCH-350581 inhibit human immunodeficiency virus type 1 entry.

1 reference

12 December 2020

The crown and stem of the V3 loop play distinct roles in human immunodeficiency virus type 1 envelope glycoprotein interactions with the CCR5 coreceptor

1 reference

12 December 2020

HIV-1-induced cell fusion is mediated by multiple regions within both the viral envelope and the CCR-5 co-receptor

1 reference

12 December 2020

Analysis of the critical domain in the V3 loop of human immunodeficiency virus type 1 gp120 involved in CCR5 utilization

1 reference

12 December 2020

Multiple extracellular domains of CCR-5 contribute to human immunodeficiency virus type 1 entry and fusion.

1 reference

12 December 2020

Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

1 reference

12 December 2020

Specific interaction of CCR5 amino-terminal domain peptides containing sulfotyrosines with HIV-1 envelope glycoprotein gp120

1 reference

12 December 2020

Angiogenic and HIV-inhibitory functions of KSHV-encoded chemokines

1 reference

12 December 2020

Multiple charged and aromatic residues in CCR5 amino-terminal domain are involved in high affinity binding of both chemokines and HIV-1 Env protein.

1 reference

12 December 2020

10.1007/S00894-006-0117-Z

Identifiers

DOI

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10 September 2017

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