(Q39296661)

10 September 2017

title

Determination of Chinese hamster ovary cell line stability and recombinant antibody expression during long-term culture (English)

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10 September 2017

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Laura A Bailey

1

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10 September 2017

Diane Hatton

series ordinal

2

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10 September 2017

Ray Field

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3

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10 September 2017

Alan J Dickson

series ordinal

4

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10 September 2017

publication date

1 August 2012

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Biotechnology and Bioengineering

10 September 2017

published in

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10 September 2017

volume

109

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10 September 2017

issue

8

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10 September 2017

page(s)

2093-2103

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Considerations on the lactate consumption by CHO cells in the presence of galactose

10 September 2017

cites work

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Regulating apoptosis in mammalian cell cultures

21 January 2018

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Stability of protein production from recombinant mammalian cells

21 January 2018

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Metabolic-flux analysis of continuously cultured hybridoma cells using (13)CO(2) mass spectrometry in combination with (13)C-lactate nuclear magnetic resonance spectroscopy and metabolite balancing

21 January 2018

1 reference

Process development for the production of recombinant antibodies using the glutamine synthetase (GS) system

21 January 2018

1 reference

A study of monoclonal antibody-producing CHO cell lines: what makes a stable high producer?

21 January 2018

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Genetic characterization of CHO production host DG44 and derivative recombinant cell lines.

21 January 2018

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Early prediction of instability of Chinese hamster ovary cell lines expressing recombinant antibodies and antibody-fusion proteins

21 January 2018

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Metabolic flux analysis of CHO cells in perfusion culture by metabolite balancing and 2D [13C, 1H] COSY NMR spectroscopy

21 January 2018

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Regulated translation initiation controls stress-induced gene expression in mammalian cells

21 January 2018

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Regulation of recombinant monoclonal antibody production in chinese hamster ovary cells: a comparative study of gene copy number, mRNA level, and protein expression.

21 January 2018

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The generation of stable, high MAb expressing CHO cell lines based on the artificial chromosome expression (ACE) technology

21 January 2018

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Role of the unfolded protein response in cell death

21 January 2018

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A mechanistic understanding of production instability in CHO cell lines expressing recombinant monoclonal antibodies

21 January 2018

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Analysis of the role of GADD153 in the control of apoptosis in NS0 myeloma cells

21 January 2018

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Elevated gadd153/chop expression and enhanced c-Jun N-terminal protein kinase activation sensitizes aged cells to ER stress

21 January 2018

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Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

21 January 2018

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Cell line-specific control of recombinant monoclonal antibody production by CHO cells.

21 January 2018

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Promoter methylation and transgene copy numbers predict unstable protein production in recombinant Chinese hamster ovary cell lines

21 January 2018

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Roles of CHOP/GADD153 in endoplasmic reticulum stress

21 January 2018

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Induction of two transformation-sensitive membrane polypeptides in normal fibroblasts by a block in glycoprotein synthesis or glucose deprivation

21 January 2018

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CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription

21 January 2018

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Effective quenching processes for physiologically valid metabolite profiling of suspension cultured Mammalian cells

21 January 2018

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Production of recombinant protein therapeutics in cultivated mammalian cells

21 January 2018

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Amino Acid Limitation Induces Expression ofCHOP, a CCAAT/Enhancer Binding Protein-related Gene, at Both Transcriptional and Post-transcriptional Levels

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/BIT.24485

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release_or6hyptzxfcircuv6yij73sl3i

10 September 2017

Fatcat ID

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