(Q39302717)

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Molecular pathways for glucose homeostasis, insulin signaling and autophagy in hepatitis C virus induced insulin resistance in a cellular model

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Europe PubMed Central

PubMed publication ID

10 September 2017

Molecular pathways for glucose homeostasis, insulin signaling and autophagy in hepatitis C virus induced insulin resistance in a cellular model (English)

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Europe PubMed Central

PubMed publication ID

10 September 2017

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based on heuristic

inferred from title

Hepatitis C virus

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based on heuristic

inferred from title

insulin resistance

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based on heuristic

inferred from title

author name string

Gokul C Das

1

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Europe PubMed Central

PubMed publication ID

10 September 2017

F Blaine Hollinger

2

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Europe PubMed Central

PubMed publication ID

10 September 2017

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publication date

3 August 2012

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Europe PubMed Central

PubMed publication ID

10 September 2017

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Europe PubMed Central

PubMed publication ID

10 September 2017

434

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Europe PubMed Central

PubMed publication ID

10 September 2017

1

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Europe PubMed Central

PubMed publication ID

10 September 2017

5-17

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Europe PubMed Central

PubMed publication ID

10 September 2017

Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action

1 reference

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Hepatitis C Virus Genotype 1a Growth and Induction of Autophagy

1 reference

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3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

1 reference

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New insights into mTOR signaling: mTORC2 and beyond

1 reference

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Impaired IRS-1/PI3-kinase signaling in patients with HCV: a mechanism for increased prevalence of type 2 diabetes

1 reference

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Distinct molecular regulation of glycogen synthase kinase-3alpha isozyme controlled by its N-terminal region: functional role in calcium/calpain signaling

1 reference

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Hepatitis C virus core protein upregulates serine phosphorylation of insulin receptor substrate-1 and impairs the downstream akt/protein kinase B signaling pathway for insulin resistance

1 reference

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Regulation of adiponectin secretion by insulin and amino acids in 3T3-L1 adipocytes

1 reference

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Effects of free fatty acids (FFA) on glucose metabolism: significance for insulin resistance and type 2 diabetes

1 reference

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Robust production of infectious hepatitis C virus (HCV) from stably HCV cDNA-transfected human hepatoma cells

1 reference

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ER stress inhibits mTORC2 and Akt signaling through GSK-3β-mediated phosphorylation of rictor.

1 reference

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Glucose transport in cultured human skeletal muscle cells. Regulation by insulin and glucose in nondiabetic and non-insulin-dependent diabetes mellitus subjects

1 reference

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Canonical and non-canonical autophagy: variations on a common theme of self-eating?

1 reference

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The renaissance of GSK3

1 reference

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

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7 January 2021

Insulin resistance plays a significant role in liver fibrosis in chronic hepatitis C and in the response to antiviral therapy

1 reference

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7 January 2021

Differential regulation of glycogen synthase kinase 3beta by insulin and Wnt signaling

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Regulation of lipid droplets by autophagy

1 reference

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7 January 2021

Insulin resistance is common in patients with predominantly genotype 3 chronic hepatitis C.

1 reference

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7 January 2021

Expression and characterization of glycogen synthase kinase-3 mutants and their effect on glycogen synthase activity in intact cells

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Expression of insulin receptor substrate-1 in hepatocytes: an investigation using monoclonal antibodies

1 reference

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The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. 'Protein modifications: beyond the usual suspects' review series

1 reference

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The emerging role of autophagy in the pathophysiology of diabetes mellitus

1 reference

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Correlation between beta-lipoprotein levels and outcome of hepatitis C treatment

1 reference

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Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

1 reference

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Regulation mechanisms and signaling pathways of autophagy

1 reference

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7 January 2021

Dengue virus-induced autophagy regulates lipid metabolism

1 reference

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7 January 2021

Common inhibitory serine sites phosphorylated by IRS-1 kinases, triggered by insulin and inducers of insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.07.003

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Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

1 reference

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LAMP proteins are required for fusion of lysosomes with phagosomes

1 reference

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SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity

1 reference

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Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics

1 reference

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mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.07.003

7 January 2021

Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia

1 reference

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7 January 2021

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.07.003

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Amino Acids and Insulin Control Autophagic Proteolysis through Different Signaling Pathways in Relation to mTOR in Isolated Rat Hepatocytes

1 reference

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Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling.

1 reference

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7 January 2021

Autophagic machinery activated by dengue virus enhances virus replication

1 reference

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Serine 332 phosphorylation of insulin receptor substrate-1 by glycogen synthase kinase-3 attenuates insulin signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.07.003

7 January 2021

Complete replication of hepatitis C virus in cell culture

1 reference

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7 January 2021

Unravelling hepatitis C virus replication from genome to function

1 reference

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Changes in autophagy after traumatic brain injury

1 reference

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Serine phosphorylation proximal to its phosphotyrosine binding domain inhibits insulin receptor substrate 1 function and promotes insulin resistance

1 reference

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7 January 2021

Chronic hepatitis B

1 reference

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Glycogen synthase kinase 3alpha-specific regulation of murine hepatic glycogen metabolism

1 reference

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Distinct roles of GSK-3alpha and GSK-3beta phosphorylation in the heart under pressure overload

1 reference

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Prevalence of type 2 diabetes mellitus among persons with hepatitis C virus infection in the United States

1 reference

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Macroautophagy: protector in the diabetes drama?

1 reference

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Hepatic fatty acid translocase CD36 upregulation is associated with insulin resistance, hyperinsulinaemia and increased steatosis in non-alcoholic steatohepatitis and chronic hepatitis C.

1 reference

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A protein conjugation system essential for autophagy

1 reference

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Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

1 reference

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Role of the PDK1-PKB-GSK3 pathway in regulating glycogen synthase and glucose uptake in the heart

1 reference

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Tissue-specific role of glycogen synthase kinase 3beta in glucose homeostasis and insulin action

1 reference

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The hepatitis C virus core protein of genotypes 3a and 1b downregulates insulin receptor substrate 1 through genotype-specific mechanisms

1 reference

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7 January 2021

Development of glucose intolerance in male transgenic mice overexpressing human glycogen synthase kinase-3beta on a muscle-specific promoter

1 reference

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Glycogen and its Metabolism

1 reference

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Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients.

1 reference

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Impaired glucose transport and protein kinase B activation by insulin, but not okadaic acid, in adipocytes from subjects with Type II diabetes mellitus

1 reference

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A chemical method for fast and sensitive detection of DNA synthesis in vivo

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Growing roles for the mTOR pathway

1 reference

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

1 reference

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Turnover of the active fraction of IRS1 involves raptor-mTOR- and S6K1-dependent serine phosphorylation in cell culture models of tuberous sclerosis

1 reference

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Stimulation of ATG12-ATG5 conjugation by ribonucleic acid

1 reference

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Hepatitis C virus infection and diabetes: direct involvement of the virus in the development of insulin resistance

1 reference

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Molecular basis of the regulation of Beclin 1-dependent autophagy by the gamma-herpesvirus 68 Bcl-2 homolog M11

1 reference

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Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response

1 reference

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Phosphorylation of sites 3a and 3b (Ser640 and Ser644) in the control of rabbit muscle glycogen synthase

1 reference

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The Hepatitis C virus NS5A protein activates a phosphoinositide 3-kinase-dependent survival signaling cascade

1 reference

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Signaling pathways mediating insulin-stimulated glucose transport

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Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling

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Interferon-dependent activation of the serine kinase PI 3'-kinase requires engagement of the IRS pathway but not the Stat pathway

1 reference

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Interferon-α Engages the Insulin Receptor Substrate-1 to Associate with the Phosphatidylinositol 3′-Kinase

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The PI3K-PDK1 connection: more than just a road to PKB

1 reference

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Autophagy protects cells from HCV-induced defects in lipid metabolism

1 reference

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Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

1 reference

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Induction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia

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Isoform differences in substrate recognition by glycogen synthase kinases 3 alpha and 3 beta in the phosphorylation of phosphatase inhibitor 2

1 reference

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Hepatitis C Virus Induces Proteolytic Cleavage of Sterol Regulatory Element Binding Proteins and Stimulates Their Phosphorylation via Oxidative Stress

1 reference

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T-cell activation leads to rapid stimulation of translation initiation factor eIF2B and inactivation of glycogen synthase kinase-3

1 reference

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Autophagosome formation: core machinery and adaptations

1 reference

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GSK-3beta promotes cell survival by modulating Bif-1-dependent autophagy and cell death

1 reference

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Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance.

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Suppression of glycogen synthase kinase activity is not sufficient for leukemia enhancer factor-1 activation

1 reference

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Morphine induces Beclin 1- and ATG5-dependent autophagy in human neuroblastoma SH-SY5Y cells and in the rat hippocampus

1 reference

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Robust hepatitis C virus infection in vitro

1 reference

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7 January 2021

Insulin resistance: a phosphorylation-based uncoupling of insulin signaling

1 reference

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Beclin 1-mediated autophagy in hepatocellular carcinoma cells: implication in anticancer efficiency of oroxylin A via inhibition of mTOR signaling.

1 reference

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7 January 2021

Identifiers

10.1016/J.VIROL.2012.07.003

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

release_jehkifvgofdpjn3azj7sga3fe4

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

ResearchGate publication ID

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