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Proviral Latency, Persistent Human Immunodeficiency Virus Infection, and the Development of Latency Reversing Agents.
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Europe PubMed Central
PMC publication ID
5410986
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28520964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
review article
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Europe PubMed Central
title
Proviral Latency, Persistent Human Immunodeficiency Virus Infection, and the Development of Latency Reversing Agents
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
5410986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28520964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
author
David M. Margolis
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1
1 reference
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Europe PubMed Central
PMC publication ID
5410986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28520964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
Nancie M Archin
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2
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Nancie M Archin
1 reference
stated in
Europe PubMed Central
PMC publication ID
5410986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28520964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
language of work or name
English
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publication date
1 March 2017
1 reference
stated in
Europe PubMed Central
PMC publication ID
5410986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28520964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
published in
Journal of Infectious Diseases
1 reference
stated in
Europe PubMed Central
PMC publication ID
5410986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28520964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
volume
215
1 reference
stated in
Europe PubMed Central
PMC publication ID
5410986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28520964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
issue
suppl_3
1 reference
stated in
Europe PubMed Central
PMC publication ID
5410986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28520964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
page(s)
S111-S118
1 reference
stated in
Europe PubMed Central
PMC publication ID
5410986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28520964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
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Dual-Affinity Re-Targeting proteins direct T cell-mediated cytolysis of latently HIV-infected cells
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The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo
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An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression
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H3K27 Demethylation at the Proviral Promoter Sensitizes Latent HIV to the Effects of Vorinostat in Ex Vivo Cultures of Resting CD4+ T Cells
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HIV latency. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells
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An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients
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Reactivation of latent HIV-1 in central memory CD4⁺ T cells through TLR-1/2 stimulation
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Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies
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Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy
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15 June 2018
Immediate antiviral therapy appears to restrict resting CD4+ cell HIV-1 infection without accelerating the decay of latent infection
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15 June 2018
Hematopoietic precursor cells isolated from patients on long-term suppressive HIV therapy did not contain HIV-1 DNA.
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15 June 2018
Paucity of HIV DNA methylation in latently infected, resting CD4+ T cells from infected individuals receiving antiretroviral therapy
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HIV-1 DNA is detected in bone marrow populations containing CD4+ T cells but is not found in purified CD34+ hematopoietic progenitor cells in most patients on antiretroviral therapy
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15 June 2018
Primary cell models of HIV latency
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15 June 2018
Involvement of histone H3 lysine 9 (H3K9) methyltransferase G9a in the maintenance of HIV-1 latency and its reactivation by BIX01294.
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15 June 2018
HIV-1 infects multipotent progenitor cells causing cell death and establishing latent cellular reservoirs.
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15 June 2018
The development of antiretroviral therapy and its impact on the HIV-1/AIDS pandemic
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15 June 2018
CpG methylation controls reactivation of HIV from latency
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15 June 2018
Epigenetic regulation of HIV-1 latency by cytosine methylation
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15 June 2018
HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
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15 June 2018
Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid
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15 June 2018
Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation
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15 June 2018
Suberoylanilide hydroxamic acid reactivates HIV from latently infected cells
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15 June 2018
APOBEC proteins and intrinsic resistance to HIV-1 infection
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15 June 2018
Suv39H1 and HP1gamma are responsible for chromatin-mediated HIV-1 transcriptional silencing and post-integration latency
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15 June 2018
Recruitment of chromatin-modifying enzymes by CTIP2 promotes HIV-1 transcriptional silencing
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15 June 2018
The Yin and Yang of P-TEFb regulation: implications for human immunodeficiency virus gene expression and global control of cell growth and differentiation
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Nuclear retention of multiply spliced HIV-1 RNA in resting CD4+ T cells
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Human immunodeficiency virus type 1 can establish latent infection in resting CD4+ T cells in the absence of activating stimuli
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Depletion of latent HIV-1 infection in vivo: a proof-of-concept study
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15 June 2018
Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity
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Clinical development of histone deacetylase inhibitors as anticancer agents
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15 June 2018
Coaxing HIV-1 from resting CD4 T cells: histone deacetylase inhibition allows latent viral expression
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15 June 2018
Can HIV be Cured? Mechanisms of HIV persistence and strategies to combat it.
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15 June 2018
HIV reproducibly establishes a latent infection after acute infection of T cells in vitro.
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15 June 2018
Induction of TAK (cyclin T1/P-TEFb) in purified resting CD4(+) T lymphocytes by combination of cytokines
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15 June 2018
Translating the Histone Code
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15 June 2018
The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation
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15 June 2018
The language of covalent histone modifications
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15 June 2018
Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410986
retrieved
15 June 2018
Mutations in the tat gene are responsible for human immunodeficiency virus type 1 postintegration latency in the U1 cell line
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410986
retrieved
15 June 2018
Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410986
retrieved
15 June 2018
Recovery of replication-competent HIV despite prolonged suppression of plasma viremia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410986
retrieved
15 June 2018
P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410986
retrieved
15 June 2018
Transcription elongation factor P-TEFb is required for HIV-1 tat transactivation in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410986
retrieved
15 June 2018
Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410986
retrieved
15 June 2018
The T cell activation factor NF-ATc positively regulates HIV-1 replication and gene expression in T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410986
retrieved
15 June 2018
A point mutation in the HIV-1 Tat responsive element is associated with postintegration latency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410986
retrieved
15 June 2018
An inducible transcription factor activates expression of human immunodeficiency virus in T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410986
retrieved
15 June 2018
CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410986
retrieved
17 June 2018
Precise Quantitation of the Latent HIV-1 Reservoir: Implications for Eradication Strategies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410986
retrieved
17 June 2018
A hardwired HIV latency program
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410986
retrieved
17 June 2018
Bromodomain and extraterminal domain inhibitors (BETi) for cancer therapy: chemical modulation of chromatin structure
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410986
retrieved
17 June 2018
How to best measure HIV reservoirs?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410986
retrieved
17 June 2018
Epigenetic silencing of HIV-1 by the histone H3 lysine 27 methyltransferase enhancer of Zeste 2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410986
retrieved
17 June 2018
Molecular mechanisms involved in HIV-1 transcriptional latency and reactivation: implications for the development of therapeutic strategies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410986
retrieved
17 June 2018
CD154-CD40-induced reactivation of latent HIV-1 infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410986
retrieved
17 June 2018
The importance of monocytes and macrophages in HIV pathogenesis, treatment, and cure.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410986
retrieved
21 August 2018
Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410986
retrieved
21 August 2018
Effect of treatment, during primary infection, on establishment and clearance of cellular reservoirs of HIV-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410986
retrieved
21 August 2018
HIV-1 Nef intersects the macrophage CD40L signalling pathway to promote resting-cell infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410986
retrieved
21 August 2018
Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410986
retrieved
21 August 2018
Host factors regulating post-integration latency of HIV
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/28520964
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The Suv39H1 methyltransferase inhibitor chaetocin causes induction of integrated HIV-1 without producing a T cell response
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/28520964
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1093/INFDIS/JIW618
1 reference
stated in
Europe PubMed Central
PMC publication ID
5410986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28520964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
Fatcat ID
release_mk5wwipzvjgwzhx63o5mgn4qzy
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/mk5wwipzvjgwzhx63o5mgn4qzy
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMC publication ID
5410986
1 reference
stated in
Europe PubMed Central
PMC publication ID
5410986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28520964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
PubMed publication ID
28520964
1 reference
stated in
Europe PubMed Central
PMC publication ID
5410986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28520964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
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