(Q38958099)

English

Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial

scientific article published on 15 September 2014

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scholarly article

1 reference

Europe PubMed Central

8 September 2017

Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial (English)

1 reference

Europe PubMed Central

8 September 2017

phase I clinical trial

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anti-retroviral agent

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phase II clinical trial

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Thomas A. Rasmussen

1

1 reference

Europe PubMed Central

8 September 2017

Martin Tolstrup

2

1 reference

Europe PubMed Central

8 September 2017

Sharon R. Lewin

12

1 reference

Europe PubMed Central

8 September 2017

object named as

Rikke Olesen

4

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Ole Schmeltz Søgaard

object named as

Ole S Søgaard

14

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Lars Østergaard

object named as

Lars Østergaard

13

0 references

Charles A. Dinarello

9

object named as

Charles Dinarello

1 reference

Europe PubMed Central

8 September 2017

Anni Winckelmann

7

object named as

Anni Winckelmann

1 reference

Europe PubMed Central

8 September 2017

Ajantha Solomon

6

object named as

Ajantha Solomon

1 reference

Europe PubMed Central

8 September 2017

Maria José Buzon

10

object named as

Maria Buzon

1 reference

Europe PubMed Central

8 September 2017

Mathias Lichterfeld

11

object named as

Mathias Lichterfeld

1 reference

Europe PubMed Central

8 September 2017

Christel R Brinkmann

3

object named as

Christel R Brinkmann

1 reference

Europe PubMed Central

8 September 2017

author name string

Christian Erikstrup

5

1 reference

Europe PubMed Central

8 September 2017

Sarah Palmer

8

1 reference

Europe PubMed Central

8 September 2017

publication date

15 September 2014

1 reference

Europe PubMed Central

8 September 2017

The lancet. HIV

1 reference

Europe PubMed Central

8 September 2017

1

1 reference

Europe PubMed Central

8 September 2017

e13-21

1 reference

Europe PubMed Central

8 September 2017

1

1 reference

Europe PubMed Central

8 September 2017

HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART) in patients with a history of sustained viral suppression

1 reference

https://api.crossref.org/works/10.1016%2FS2352-3018%2814%2970014-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS2352-3018%2814%2970014-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS2352-3018%2814%2970014-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS2352-3018%2814%2970014-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Redefining the viral reservoirs that prevent HIV-1 eradication

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

HIV: Shock and kill.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

New ex vivo approaches distinguish effective and ineffective single agents for reversing HIV-1 latency in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS2352-3018%2814%2970014-1

7 January 2021

based on heuristic

inferred from DOI database lookup

NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Entinostat is a histone deacetylase inhibitor selective for class 1 histone deacetylases and activates HIV production from latently infected primary T cells.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Unique characteristics of histone deacetylase inhibitors in reactivation of latent HIV-1 in Bcl-2-transduced primary resting CD4+ T cells

1 reference

https://api.crossref.org/works/10.1016%2FS2352-3018%2814%2970014-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS2352-3018%2814%2970014-1

7 January 2021

based on heuristic

inferred from DOI database lookup

HIV-1 expression within resting CD4+ T cells after multiple doses of vorinostat

1 reference

https://api.crossref.org/works/10.1016%2FS2352-3018%2814%2970014-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Measuring reversal of HIV-1 latency ex vivo using cells from infected individuals

1 reference

https://api.crossref.org/works/10.1016%2FS2352-3018%2814%2970014-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation

1 reference

https://api.crossref.org/works/10.1016%2FS2352-3018%2814%2970014-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Progress of HDAC inhibitor panobinostat in the treatment of cancer

1 reference

https://api.crossref.org/works/10.1016%2FS2352-3018%2814%2970014-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparison of HDAC inhibitors in clinical development: effect on HIV production in latently infected cells and T-cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS2352-3018%2814%2970014-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Histone deacetylase inhibitor romidepsin induces HIV expression in CD4 T cells from patients on suppressive antiretroviral therapy at concentrations achieved by clinical dosing

1 reference

https://api.crossref.org/works/10.1016%2FS2352-3018%2814%2970014-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparative analysis of triplex nucleic acid test assays in United States blood donors

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Challenges in clinical trial design for HIV-1 cure research

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Cellular levels of HIV unspliced RNA from patients on combination antiretroviral therapy with undetectable plasma viremia predict the therapy outcome

1 reference

https://api.crossref.org/works/10.1016%2FS2352-3018%2814%2970014-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Profile of panobinostat and its potential for treatment in solid tumors: an update

1 reference

https://api.crossref.org/works/10.1016%2FS2352-3018%2814%2970014-1

7 January 2021

based on heuristic

inferred from DOI database lookup

HIV and HLA class I: an evolving relationship

1 reference

https://api.crossref.org/works/10.1016%2FS2352-3018%2814%2970014-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Pegylated Interferon alfa-2a monotherapy results in suppression of HIV type 1 replication and decreased cell-associated HIV DNA integration

1 reference

https://api.crossref.org/works/10.1016%2FS2352-3018%2814%2970014-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Histone deacetylase inhibitors impair the elimination of HIV-infected cells by cytotoxic T-lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS2352-3018%2814%2970014-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Phase Ia/II, two-arm, open-label, dose-escalation study of oral panobinostat administered via two dosing schedules in patients with advanced hematologic malignancies.

1 reference

https://api.crossref.org/works/10.1016%2FS2352-3018%2814%2970014-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Extensive astrocyte infection is prominent in human immunodeficiency virus-associated dementia

1 reference

https://api.crossref.org/works/10.1016%2FS2352-3018%2814%2970014-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Monocytes harbour replication-competent, non-latent HIV-1 in patients on highly active antiretroviral therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS2352-3018%2814%2970014-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Infection of monocyte-derived macrophages with human immunodeficiency virus type 1 (HIV-1). Monocyte-tropic and lymphocyte-tropic strains of HIV-1 show distinctive patterns of replication in a panel of cell types

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S2352-3018(14)70014-1

1 reference

Europe PubMed Central

8 September 2017

1 reference

Europe PubMed Central

8 September 2017

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