(Q39330291)

11 September 2017

title

Cip2a promotes cell cycle progression in triple-negative breast cancer cells by regulating the expression and nuclear export of p27Kip1. (English)

1 reference

triple-negative breast cancer

11 September 2017

main subject

1 reference

H Liu

1

1 reference

11 September 2017

H Qiu

2

1 reference

11 September 2017

Y Song

3

1 reference

11 September 2017

Y Liu

4

1 reference

11 September 2017

H Wang

5

1 reference

11 September 2017

M Lu

6

1 reference

11 September 2017

M Deng

7

1 reference

11 September 2017

Y Gu

8

1 reference

11 September 2017

J Yin

9

1 reference

11 September 2017

K Luo

10

1 reference

11 September 2017

Z Zhang

11

1 reference

11 September 2017

X Jia

12

1 reference

11 September 2017

G Zheng

13

1 reference

11 September 2017

Z He

14

1 reference

11 September 2017

language of work or name

English

0 references

publication date

3 October 2016

1 reference

11 September 2017

1 reference

11 September 2017

volume

36

1 reference

11 September 2017

issue

14

1 reference

11 September 2017

page(s)

1952-1964

1 reference

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

11 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Triple-negative breast cancer: molecular features, pathogenesis, treatment and current lines of research.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Clinicopathological analyses of triple negative breast cancer using surveillance data from the Registration Committee of the Japanese Breast Cancer Society

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Regulation of protein kinase cascades by protein phosphatase 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Protein phosphatase 2A: a target for anticancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Deregulation of the phosphatase, PP2A is a common event in breast cancer, predicting sensitivity to FTY720.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

CIP2A inhibits PP2A in human malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Senescence sensitivity of breast cancer cells is defined by positive feedback loop between CIP2A and E2F1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Cancerous inhibitor of protein phosphatase 2A, an emerging human oncoprotein and a potential cancer therapy target.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

CIP2A is a candidate therapeutic target in clinically challenging prostate cancer cell populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

CIP2A is associated with human breast cancer aggressivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Clinical implications of CIP2A protein expression in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

CIP2A is a target of bortezomib in human triple negative breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Relocalized p27Kip1 tumor suppressor functions as a cytoplasmic metastatic oncogene in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Cytoplasmic p27 promotes epithelial-mesenchymal transition and tumor metastasis via STAT3-mediated Twist1 upregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Control of DNA synthesis and mitosis by the Skp2-p27-Cdk1/2 axis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Skp2-mediated degradation of p27 regulates progression into mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Regulation of the cyclin-dependent kinase inhibitor p27 by degradation and phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

The B56gamma3 regulatory subunit of protein phosphatase 2A (PP2A) regulates S phase-specific nuclear accumulation of PP2A and the G1 to S transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

CIP2A mediates effects of bortezomib on phospho-Akt and apoptosis in hepatocellular carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

CIP2A cooperates with H-Ras to promote epithelial-mesenchymal transition in cervical-cancer progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Akt1 sequentially phosphorylates p27kip1 within a conserved but non-canonical region

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Cytoplasmic p27 is oncogenic and cooperates with Ras both in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Activation of p27Kip1 Expression by E2F1. A negative feedback mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

PARP inhibition: PARP1 and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Iniparib plus chemotherapy in metastatic triple-negative breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

CIP2A is Overexpressed in Non-Small Cell Lung Cancer and Correlates with Poor Prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

CIP2A overexpression is associated with c-Myc expression in colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

CIP2A signature reveals the MYC dependency of CIP2A-regulated phenotypes and its clinical association with breast cancer subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Increase in CIP2A expression is associated with doxorubicin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

CIP2A modulates cell-cycle progression in human cancer cells by regulating the stability and activity of Plk1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Skp2-dependent degradation of p27kip1 is essential for cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Regulation of cyclin-dependent kinase activity during mitotic exit and maintenance of genome stability by p21, p27, and p107

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

p27kip1 deficiency impairs G2/M arrest in response to DNA damage, leading to an increase in genetic instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

p27Kip1 stabilization is essential for the maintenance of cell cycle arrest in response to DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

PCTAIRE1 phosphorylates p27 and regulates mitosis in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Phosphorylation of p27Kip1 on serine 10 is required for its binding to CRM1 and nuclear export

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

p27(Kip1) signaling: Transcriptional and post-translational regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Pharmacologic inhibition of RAF-->MEK-->ERK signaling elicits pancreatic cancer cell cycle arrest through induced expression of p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Making decisions through Myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Defective DNA double-strand break repair underlies enhanced tumorigenesis and chromosomal instability in p27-deficient mice with growth factor-induced oligodendrogliomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Cdk1 participates in BRCA1-dependent S phase checkpoint control in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Overexpression of PP2A inhibitor SET oncoprotein is associated with tumor progression and poor prognosis in human non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

CIP2A is overexpressed in gastric cancer and its depletion leads to impaired clonogenicity, senescence, or differentiation of tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Cancerous inhibitor of PP2A (CIP2A) at diagnosis of chronic myeloid leukemia is a critical determinant of disease progression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

CIP2A is overexpressed in esophageal squamous cell carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.355

Role of "oncogenic nexus" of CIP2A in breast oncogenesis: how does it work?

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27694903

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Protein phosphatase 2A regulatory subunits and cancer.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27694903

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2016.355

1 reference

11 September 2017

1 reference