(Q39332805)

11 September 2017

title

Methylome analysis and integrative profiling of human HCCs identify novel protumorigenic factors (English)

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11 September 2017

5

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11 September 2017

Miriam Kesselmeier

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Justo Lorenzo Bermejo

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Justo Lorenzo Bermejo

10

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author name string

Olaf Neumann

1

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11 September 2017

Robert Geffers

3

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11 September 2017

Rossella Pellegrino

4

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Katrin Hoffmann

6

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11 September 2017

Volker Ehemann

7

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11 September 2017

Peter Schemmer

8

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11 September 2017

Peter Schirmacher

9

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11 September 2017

Thomas Longerich

11

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11 September 2017

language of work or name

English

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publication date

14 October 2012

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11 September 2017

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11 September 2017

volume

56

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11 September 2017

issue

5

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11 September 2017

page(s)

1817-1827

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Epidemiology of primary liver cancer

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cites work

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The Polycomb complex PRC2 and its mark in life

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Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma.

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Etiology-dependent molecular mechanisms in human hepatocarcinogenesis

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A new mathematical model for relative quantification in real-time RT-PCR

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Nuclear expression of the ubiquitin ligase seven in absentia homolog (SIAH)-1 induces proliferation and migration of liver cancer cells

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Bioconductor: open software development for computational biology and bioinformatics

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Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

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DNA methylation changes in normal liver tissues and hepatocellular carcinoma with different viral infection

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Inactivation of Ras GTPase-activating proteins promotes unrestrained activity of wild-type Ras in human liver cancer

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Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice

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Variable DNA methylation patterns associated with progression of disease in hepatocellular carcinomas

21 January 2018

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Hepatocellular carcinoma displays distinct DNA methylation signatures with potential as clinical predictors

21 January 2018

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Methylation profile of single hepatocytes derived from hepatitis B virus-related hepatocellular carcinoma

21 January 2018

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Genome-wide DNA methylation profiles in hepatocellular carcinoma.

21 January 2018

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Beta-catenin accumulation in the progression of human hepatocarcinogenesis correlates with loss of E-cadherin and accumulation of p53, but not with expression of conventional WNT-1 target genes.

21 January 2018

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Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis

21 January 2018

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Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets

21 January 2018

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Extensive methylation is associated with beta-catenin mutations in hepatocellular carcinoma: evidence for two distinct pathways of human hepatocarcinogenesis.

21 January 2018

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Role of histone H3 lysine 27 methylation in Polycomb-group silencing

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Histone methyltransferase activity of a Drosophila Polycomb group repressor complex

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Polycomb complexes repress developmental regulators in murine embryonic stem cells

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Role of polycomb group proteins in stem cell self-renewal and cancer.

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Epigenetic stem cell signature in cancer

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Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells

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Aberrant DNA methylation profile and frequent methylation of KLK10 and OXGR1 genes in hepatocellular carcinoma

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Reduced expression of reelin (RELN) gene is associated with high recurrence rate of hepatocellular carcinoma

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Disturbance of circadian gene expression in hepatocellular carcinoma.

21 January 2018

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Alpha-fetoprotein and tumour size are associated with microvascular invasion in explanted livers of patients undergoing transplantation with hepatocellular carcinoma

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Molecular components of the mammalian circadian clock

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Deregulated expression of the PER1, PER2 and PER3 genes in breast cancers.

21 January 2018

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Riding tandem: circadian clocks and the cell cycle

21 January 2018

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The circadian gene per1 plays an important role in cell growth and DNA damage control in human cancer cells

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Deletion of the PER3 gene on chromosome 1p36 in recurrent ER-positive breast cancer

21 January 2018

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Per3, a circadian gene, is required for Chk2 activation in human cells

21 January 2018

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Human acid-labile subunit deficiency: clinical, endocrine and metabolic consequences.

21 January 2018

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Dysregulation of growth factor signaling in human hepatocellular carcinoma.

21 January 2018

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The protein Z/protein Z-dependent protease inhibitor complex. Systemic or local control of coagulation?

21 January 2018

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Distinct DNA methylation patterns in cirrhotic liver and hepatocellular carcinoma

21 January 2018

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21 January 2018

Hepatocellular carcinoma

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7 January 2021

Methylation framework of cell cycle gene inhibitors in cirrhosis and associated hepatocellular carcinoma

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7 January 2021

Factors of transforming growth factor beta signalling are co-regulated in human hepatocellular carcinoma

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7 January 2021

Definition of the landscape of promoter DNA hypomethylation in liver cancer

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7 January 2021

Identifiers

DOI

10.1002/HEP.25870

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11 September 2017

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