(Q39337284)

11 September 2017

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title

Cytokine storm and sepsis disease pathogenesis (English)

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11 September 2017

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2

Filip K Swirski

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11 September 2017

author name string

Benjamin G Chousterman

series ordinal

1

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11 September 2017

Georg F Weber

series ordinal

3

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11 September 2017

language of work or name

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29 May 2017

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Seminars in Immunopathology

11 September 2017

published in

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11 September 2017

volume

39

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11 September 2017

issue

5

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11 September 2017

page(s)

517-528

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https://scigraph.springernature.com/pub.10.1007/s00281-017-0639-8

11 September 2017

exact match

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cites work

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21 January 2018

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Toll-like receptor signalling

21 January 2018

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Differential expression of Toll-like receptor (TLR)-2 and TLR-4 on monocytes in human sepsis

21 January 2018

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Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation

21 January 2018

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Dectin-1 mediates the biological effects of beta-glucans

21 January 2018

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Dectin-1 is a major beta-glucan receptor on macrophages

21 January 2018

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The role of the beta-glucan receptor Dectin-1 in control of fungal infection

21 January 2018

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Innate signaling by the C-type lectin DC-SIGN dictates immune responses

21 January 2018

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An evolving arsenal: viral RNA detection by RIG-I-like receptors

21 January 2018

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The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome

21 January 2018

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THE ENDOTHELIUM IN SEPSIS.

21 January 2018

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Bench-to-bedside review: endothelial cell dysfunction in severe sepsis: a role in organ dysfunction?

21 January 2018

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Bench-to-bedside review: Association of genetic variation with sepsis

21 January 2018

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Genetic polymorphisms and sepsis.

21 January 2018

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Importance of hemostatic gene polymorphisms for susceptibility to and outcome of severe sepsis

21 January 2018

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Genetic predisposition to respiratory infection and sepsis

21 January 2018

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Mechanisms and regulation of the gene-expression response to sepsis.

21 January 2018

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Influence of the TNF-alpha and TNF-beta polymorphisms upon infectious risk and outcome in surgical intensive care patients.

21 January 2018

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Influence of interleukin-1 receptor antagonist gene polymorphism on disease

21 January 2018

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A functional synonymous coding variant in the IL1RN gene is associated with survival in septic shock.

21 January 2018

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Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock

21 January 2018

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Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Association of IL-10 polymorphism with severity of illness in community acquired pneumonia.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Interleukin-10 -1082 G/A gene polymorphisms in Egyptian children with CAP: A case-control study

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Lymphocyte in vitro cytotoxicity: characterization of human lymphotoxin

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

An endotoxin-induced serum factor that causes necrosis of tumors

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Identity of tumour necrosis factor and the macrophage-secreted factor cachectin

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

21 January 2018

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Shock and tissue injury induced by recombinant human cachectin

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

21 January 2018

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Cachectin/tumor necrosis factor and other cytokines in infectious disease

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Historical insights into cytokines

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Interleukin-1 (IL-1) pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling

21 January 2018

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Early interleukin-6 and slope of monocyte human leukocyte antigen-DR: a powerful association to predict the development of sepsis after major trauma

21 January 2018

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Serial cytokine levels in patients with severe sepsis

21 January 2018

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21 January 2018

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The soluble interleukin 6 receptor: mechanisms of production and implications in disease

21 January 2018

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Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Unregulated IL-23/IL-17 immune response in autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

IL-17 family member cytokines: regulation and function in innate immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Interferon-γ: an overview of signals, mechanisms and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Regulation of interferon-gamma during innate and adaptive immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

The role of interferon-γ in the pathogenesis of acute intra-abdominal sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

CXCL1 regulates pulmonary host defense to Klebsiella Infection via CXCL2, CXCL5, NF-kappaB, and MAPKs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Recruitment of Gr-1+ monocytes is essential for control of acute toxoplasmosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

CX3CR1-dependent renal macrophage survival promotes Candida control and host survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Ly6Chigh Monocytes Protect against Kidney Damage during Sepsis via a CX3CR1-Dependent Adhesion Mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Colony-stimulating factors in inflammation and autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Innate response activator B cells protect against microbial sepsis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Exudate macrophages attenuate lung injury by the release of IL-1 receptor antagonist in gram-negative pneumonia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Type 2 cytokines: mechanisms and therapeutic strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Regulation of inflammation by interleukin-4: a review of "alternatives"

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

IL-10: the master regulator of immunity to infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Anti-inflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Human IL-3 (multi-CSF): identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Interleukin-3 amplifies acute inflammation and is a potential therapeutic target in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Plasma cytokine levels predict response to corticosteroids in septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Acute inflammatory response to endotoxin in mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

From therapy to experimental model: a hundred years of endotoxin administration to human subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

C1-esterase inhibitor attenuates the inflammatory response during human endotoxemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

A network-based analysis of systemic inflammation in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Human monocytes undergo functional re-programming during sepsis mediated by hypoxia-inducible factor-1α.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Early and dynamic changes in gene expression in septic shock patients: a genome-wide approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Gene profiling in human blood leucocytes during recovery from septic shock.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

The next generation of sepsis clinical trial designs: what is next after the demise of recombinant human activated protein C?*.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Effect of cortisone on acute streptococcal infections and poststreptococcal complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Antiinflammatory action of glucocorticoids--new mechanisms for old drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Hydrocortisone therapy for patients with septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Confirmatory interleukin-1 receptor antagonist trial in severe sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial. The Interleukin-1 Receptor Antagonist Sepsis Investigator Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Effect of eritoran, an antagonist of MD2-TLR4, on mortality in patients with severe sepsis: the ACCESS randomized trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Efficacy and safety of monoclonal antibody to human tumor necrosis factor alpha in patients with sepsis syndrome. A randomized, controlled, double-blind, multicenter clinical trial. TNF-alpha MAb Sepsis Study Group.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Treatment of septic shock with human monoclonal antibody HA-1A. A randomized, double-blind, placebo-controlled trial. CHESS Trial Study Group.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Early use of polymyxin B hemoperfusion in patients with septic shock due to peritonitis: a multicenter randomized control trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Antitumor necrosis factor therapy is associated with improved survival in clinical sepsis trials: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Inflammation, endothelium, and coagulation in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Efficacy and safety of recombinant human activated protein C for severe sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Drotrecogin alfa (activated) in adults with septic shock.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Targeting Robo4-dependent Slit signaling to survive the cytokine storm in sepsis and influenza

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Slit2-Robo4 pathway modulates lipopolysaccharide-induced endothelial inflammation and its expression is dysregulated during endotoxemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Sphingosine-1-phosphate signaling and its role in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Multiplex cytokine profiling in patients with sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0639-8

Polymorphisms of genes encoding tumor necrosis factor-alpha, interleukin-10, cluster of differentiation-14 and interleukin-1ra in critically ill patients

21 January 2018

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12 December 2020

Recombinant interleukin-1 receptor antagonist (IL-1ra): effective therapy against gram-negative sepsis in rats

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12 December 2020

Protective effects of IL-6 blockade in sepsis are linked to reduced C5a receptor expression

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12 December 2020

Induction of interleukin-1 and interleukin-1 receptor antagonist

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12 December 2020

Interleukin-1 receptor antagonist gene polymorphism and mortality in patients with severe sepsis

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12 December 2020

Severe sepsis induces deficient interferon-gamma and interleukin-12 production, but interleukin-12 therapy improves survival in peritonitis

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12 December 2020

Influenza-associated encephalopathy--pathophysiology and disease mechanisms

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12 December 2020

Possible importance of macrophage-derived mediators in acute malaria

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12 December 2020

Population trends in the incidence and outcomes of acute myocardial infarction

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12 December 2020

The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection

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12 December 2020

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12 December 2020

Increased expression of toll-like receptor-2 and -4 on leukocytes from patients with sepsis

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12 December 2020

Regulatory role of C5a in LPS-induced IL-6 production by neutrophils during sepsis

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12 December 2020

Cytokine storm of graft-versus-host disease: a critical effector role for interleukin-1.

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12 December 2020

Association of TNF2, a TNF-alpha promoter polymorphism, with septic shock susceptibility and mortality: a multicenter study

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12 December 2020

Experimental endotoxemia in humans: analysis of cytokine release and coagulation, fibrinolytic, and complement pathways.

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12 December 2020

Cytotoxic Effect of Lymphocyte-Antigen Interaction in Delayed Hypersensitivity

1 reference

12 December 2020

10.1007/S00281-017-0639-8

Identifiers

DOI

1 reference

11 September 2017

1 reference