(Q39339727)

11 September 2017

Naturally occurring endo-siRNA silences LINE-1 retrotransposons in human cells through DNA methylation (English)

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11 September 2017

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Jane E Dahlstrom

2

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author name string

Long Chen

series ordinal

1

1 reference

PubMed ID

22647391

11 September 2017

Sung-Hun Lee

series ordinal

3

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PubMed ID

22647391

11 September 2017

Danny Rangasamy

series ordinal

4

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11 September 2017

1 July 2012

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11 September 2017

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11 September 2017

7

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11 September 2017

7

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11 September 2017

758-771

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Hot L1s account for the bulk of retrotransposition in the human population

11 September 2017

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LINE-1 retrotransposition activity in human genomes

21 January 2018

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Origin of the human L1 elements: proposed progenitor genes deduced from a consensus DNA sequence

21 January 2018

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Nucleic acid chaperone activity of the ORF1 protein from the mouse LINE-1 retrotransposon

21 January 2018

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Human L1 retrotransposon encodes a conserved endonuclease required for retrotransposition

21 January 2018

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Reverse Transcriptase Encoded by a Human Transposable Element

21 January 2018

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High frequency retrotransposition in cultured mammalian cells

21 January 2018

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Retrotransposons Revisited: The Restraint and Rehabilitation of Parasites

21 January 2018

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The impact of retrotransposons on human genome evolution

21 January 2018

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Human LINE retrotransposons generate processed pseudogenes

21 January 2018

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Discovery of short pseudogenes derived from messenger RNAs.

21 January 2018

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Biology of mammalian L1 retrotransposons

21 January 2018

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Somatic expression of LINE-1 elements in human tissues.

21 January 2018

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L1 retrotransposition occurs mainly in embryogenesis and creates somatic mosaicism

21 January 2018

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Natural mutagenesis of human genomes by endogenous retrotransposons

21 January 2018

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L1 retrotransposition is suppressed by endogenously encoded small interfering RNAs in human cultured cells

21 January 2018

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Epigenetic silencing of engineered L1 retrotransposition events in human embryonic carcinoma cells.

21 January 2018

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Association of nuclear localization of a long interspersed nuclear element-1 protein in breast tumors with poor prognostic outcomes

21 January 2018

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Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia

21 January 2018

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Hypomethylation of intragenic LINE-1 represses transcription in cancer cells through AGO2.

21 January 2018

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Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer

21 January 2018

1 reference

Endogenous small interfering RNAs in animals

21 January 2018

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Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells

21 January 2018

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Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes

21 January 2018

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Control of chicken CR1 retrotransposons is independent of Dicer-mediated RNA interference pathway

21 January 2018

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Small RNAs in transcriptional gene silencing and genome defence

21 January 2018

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Expression of LINE-1 retrotransposons in human breast cancer.

21 January 2018

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Efficient translation initiation directed by the 900-nucleotide-long and GC-rich 5' untranslated region of the human retrotransposon LINE-1 mRNA is strictly cap dependent rather than internal ribosome entry site mediated

21 January 2018

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Translation of LINE-1 DNA elements in vitro and in human cells

21 January 2018

1 reference

Causes and consequences of DNA hypomethylation in human cancer

21 January 2018

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Specific hypermethylation of LINE-1 elements during abnormal overgrowth and differentiation of human placenta.

21 January 2018

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A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice

21 January 2018

1 reference

Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes

21 January 2018

1 reference

Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells

21 January 2018

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Small RNAs as guardians of the genome

21 January 2018

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Conserved themes in small-RNA-mediated transposon control

21 January 2018

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Antisense promoter of human L1 retrotransposon drives transcription of adjacent cellular genes

21 January 2018

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An endogenous small interfering RNA pathway in Drosophila

21 January 2018

1 reference

High-risk myeloma is associated with global elevation of miRNAs and overexpression of EIF2C2/AGO2.

21 January 2018

1 reference

deepBase: a database for deeply annotating and mining deep sequencing data

21 January 2018

1 reference

Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells

21 January 2018

1 reference

Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L

21 January 2018

1 reference

L1 retrotransposition in human neural progenitor cells

21 January 2018

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An S/MAR-based L1 retrotransposition cassette mediates sustained levels of insertional mutagenesis without suffering from epigenetic silencing of DNA methylation

21 January 2018

1 reference

BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing.

21 January 2018

1 reference

Bisulfite sequencing Data Presentation and Compilation (BDPC) web server--a useful tool for DNA methylation analysis.

21 January 2018

1 reference

Genomic instability in histologically normal breast tissues: implications for carcinogenesis

21 January 2018

1 reference

LINE-1 hypomethylation during primary colon cancer progression

21 January 2018

1 reference

LINE-1 methylation patterns of different loci in normal and cancerous cells

21 January 2018

1 reference

Gene knockdown by ecdysone-based inducible RNAi in stable mammalian cell lines

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.4161/EPI.20706

1 reference

11 September 2017

1 reference

PubMed ID

22647391