(Q39344672)

11 September 2017

title

Fatal respiratory depression after multiple intravenous morphine injections (English)

1 reference

11 September 2017

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Rainer Freynhagen

3

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Jörn Lötsch

object named as

Jörn Lötsch

1

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author name string

Rafael Dudziak

2

1 reference

11 September 2017

Jürgen Marschner

4

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11 September 2017

Gerd Geisslinger

5

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11 September 2017

publication date

1 January 2006

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Clinical Pharmacokinetics

11 September 2017

published in

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11 September 2017

volume

45

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11 September 2017

issue

11

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11 September 2017

page(s)

1051-1060

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Simultaneous modeling of pharmacokinetics and pharmacodynamics: application to d-tubocurarine

11 September 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.2165%2F00003088-200645110-00001

Pharmacokinetic parameters relevant to recovery from opioids.

21 January 2018

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Postoperative patient-controlled analgesia with alfentanil: analgesic efficacy and minimum effective concentrations.

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Sex differences in morphine analgesia: an experimental study in healthy volunteers

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Preliminary pharmacokinetics and pharmacodynamics of an ultra-short-acting opioid: remifentanil (GI87084B).

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The transfer half-life of morphine-6-glucuronide from plasma to effect site assessed by pupil size measurement in healthy volunteers

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Context-sensitive half-time in multicompartment pharmacokinetic models for intravenous anesthetic drugs

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EEG quantitation of narcotic effect: the comparative pharmacodynamics of fentanyl and alfentanil

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Pharmacokinetics and pharmacodynamics of methadone in patients with chronic pain

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Influence of age and gender on the pharmacokinetics and pharmacodynamics of remifentanil. I. Model development.

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Remifentanil versus alfentanil: comparative pharmacokinetics and pharmacodynamics in healthy adult male volunteers

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of inhaled versus intravenous morphine in healthy volunteers.

1 reference

12 December 2020

Validation of the alfentanil canonical univariate parameter as a measure of opioid effect on the electroencephalogram

1 reference

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A comparison of spectral edge, delta power, and bispectral index as EEG measures of alfentanil, propofol, and midazolam drug effect.

1 reference

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Decreased fentanyl and alfentanil dose requirements with age. A simultaneous pharmacokinetic and pharmacodynamic evaluation

1 reference

12 December 2020

mu-Opioid receptor-stimulated guanosine-5'-O-(gamma-thio)-triphosphate binding in rat thalamus and cultured cell lines: signal transduction mechanisms underlying agonist efficacy

1 reference

12 December 2020

Influence of arteriovenous sampling on remifentanil pharmacokinetics and pharmacodynamics.

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: role of circulating active metabolites

1 reference

12 December 2020

Pharmacokinetic modeling to predict morphine and morphine-6-glucuronide plasma concentrations in healthy young volunteers

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Pharmacokinetic-pharmacodynamic modeling in drug development: application to the investigational opioid trefentanil

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Modulation of the central nervous effects of levomethadone by genetic polymorphisms potentially affecting its metabolism, distribution, and drug action.

1 reference

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Analgesic effects of morphine and morphine-6-glucuronide in a transcutaneous electrical pain model in healthy volunteers

1 reference

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Regulation of ventilation during rebreathing at imposed respiratory frequencies

1 reference

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The 5-hydroxytryptamine 4 receptor agonist mosapride does not antagonize morphine-induced respiratory depression

1 reference

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Pharmacokinetics, Pharmacodynamics, and Rational Opioid Selection

1 reference

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Pharmacokinetic-pharmacodynamic modeling of morphine-6-glucuronide-induced analgesia in healthy volunteers: absence of sex differences

1 reference

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mu Opioid receptor: role for the amino terminus as a determinant of ligand binding affinity

1 reference

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Recovery from opioid anesthesia: the clinical implication of context-sensitive half-times

1 reference

12 December 2020

Pharmacokinetic-pharmacodynamic modeling of the respiratory depressant effect of alfentanil.

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12 December 2020

[Modern concepts in pharmacokinetics of intravenous anesthetics]

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12 December 2020

Interindividual variability of the clinical pharmacokinetics of methadone: implications for the treatment of opioid dependence

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12 December 2020

A pharmacodynamic model for pancuronium

1 reference

12 December 2020

Antagonisation of fentanyl-induced respiratory depression by nalbuphine.

1 reference

12 December 2020

The pharmacokinetics of the new short-acting opioid remifentanil (GI87084B) in healthy adult male volunteers

1 reference

12 December 2020

Electroencephalographic quantitation of opioid effect: comparative pharmacodynamics of fentanyl and sufentanil

1 reference

12 December 2020

Pharmacodynamics of orally administered sustained- release hydromorphone in humans

1 reference

12 December 2020

10.2165/00003088-200645110-00001

Identifiers

DOI

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Dimensions Publication ID

11 September 2017

1024378648

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