(Q39347932)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22588298%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

A crucial role for bone morphogenetic protein-Smad1 signalling in the DNA damage response (English)

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1 February 2020

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8

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1 February 2020

author name string

Jenny Fung Ling Chau

1

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1 February 2020

Deyong Jia

2

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1 February 2020

Zhongfeng Wang

3

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1 February 2020

Zhi Liu

4

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1 February 2020

Yuanyu Hu

5

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1 February 2020

Xin Zhang

6

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1 February 2020

Hao Jia

7

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1 February 2020

Wai Fook Leong

9

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1 February 2020

Bi Jin Au

10

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1 February 2020

Yuji Mishina

11

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1 February 2020

Ye-Guang Chen

12

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1 February 2020

Christine Biondi

13

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1 February 2020

Elizabeth Robertson

14

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1 February 2020

Dong Xie

15

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1 February 2020

Huijuan Liu

16

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1 February 2020

Lin He

17

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1 February 2020

Xueying Wang

18

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1 February 2020

Qiang Yu

19

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1 February 2020

Baojie Li

20

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1 February 2020

language of work or name

English

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publication date

15 May 2012

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1 February 2020

published in

Nature Communications

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1 February 2020

volume

3

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1 February 2020

page(s)

836

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PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling

1 February 2020

cites work

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12 December 2020

The many substrates and functions of ATM

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12 December 2020

Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal

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12 December 2020

Mdm2 links genotoxic stress and metabolism to p53.

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12 December 2020

Balancing BMP Signaling through Integrated Inputs into the Smad1 Linker

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12 December 2020

Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis.

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12 December 2020

Ectodermal factor restricts mesoderm differentiation by inhibiting p53

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12 December 2020

p53 ubiquitination: Mdm2 and beyond

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12 December 2020

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

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12 December 2020

Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo.

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12 December 2020

Smad transcription factors

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12 December 2020

The DNA damage response: sensing and signaling

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12 December 2020

Homeobox B9 induces epithelial-to-mesenchymal transition-associated radioresistance by accelerating DNA damage responses.

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12 December 2020

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12 December 2020

Integration of TGF-beta and Ras/MAPK signaling through p53 phosphorylation.

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12 December 2020

Protein serine/threonine phosphatase PPM1A dephosphorylates Smad1 in the bone morphogenetic protein signaling pathway

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12 December 2020

New insights into TGF-beta-Smad signalling

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12 December 2020

Specificity and versatility in tgf-beta signaling through Smads

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12 December 2020

Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus

1 reference

12 December 2020

Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice

1 reference

12 December 2020

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

1 reference

12 December 2020

TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility

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12 December 2020

ATM: genome stability, neuronal development, and cancer cross paths

1 reference

12 December 2020

p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling

1 reference

12 December 2020

S6K1 is a multifaceted regulator of Mdm2 that connects nutrient status and DNA damage response

1 reference

12 December 2020

The bone morphogenetic protein pathway is inactivated in the majority of sporadic colorectal cancers

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12 December 2020

DNA damage signalling guards against activated oncogenes and tumour progression

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12 December 2020

In or out? The dynamics of Smad nucleocytoplasmic shuttling

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12 December 2020

Integrating positional information at the level of Smad1/5/8.

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12 December 2020

Unique players in the BMP pathway: small C-terminal domain phosphatases dephosphorylate Smad1 to attenuate BMP signaling.

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12 December 2020

TGFbeta-1 dependent fast stimulation of ATM and p53 phosphorylation following exposure to ionizing radiation does not involve TGFbeta-receptor I signalling.

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12 December 2020

TGFbeta1-induced activation of ATM and p53 mediates apoptosis in a Smad7-dependent manner.

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12 December 2020

p53 regulation orchestrates the TGF-beta response

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12 December 2020

BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling

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12 December 2020

Links between tumor suppressors: p53 is required for TGF-beta gene responses by cooperating with Smads.

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12 December 2020

Essential roles of BMPR-IA signaling in differentiation and growth of hair follicles and in skin tumorigenesis

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12 December 2020

Mice deficient in Abl are osteoporotic and have defects in osteoblast maturation

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12 December 2020

Substrate specificities and identification of putative substrates of ATM kinase family members

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12 December 2020

Identification of phosphatases for Smad in the BMP/DPP pathway

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12 December 2020

p53 in health and disease

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12 December 2020

Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes

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12 December 2020

Decoding the quantitative nature of TGF-beta/Smad signaling.

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12 December 2020

Protein phosphatase magnesium-dependent 1A-mediated inhibition of BMP signaling is independent of Smad dephosphorylation.

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12 December 2020

Surviving the breakup: the DNA damage checkpoint.

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12 December 2020

A phosphatase controls the fate of receptor-regulated Smads

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12 December 2020

Acetylation of p53 inhibits its ubiquitination by Mdm2.

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12 December 2020

Bone morphogenetic proteins

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12 December 2020

DNA double-strand breaks: signaling, repair and the cancer connection

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12 December 2020

Bone morphogenetic protein signalling in colorectal cancer.

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12 December 2020

Atm-deficient mice: an osteoporosis model with defective osteoblast differentiation and increased osteoclastogenesis.

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12 December 2020

Transforming growth factor-beta1 mediates cellular response to DNA damage in situ.

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12 December 2020

ATM/ATR and SMAD3 pathways contribute to 3-indole-induced G₁ arrest in cancer cells and xenograft models.

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12 December 2020

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

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12 December 2020

Surfing the p53 network

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12 December 2020

Bone morphogenetic protein-Smad pathway as drug targets for osteoporosis and cancer therapy

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12 December 2020

Cyclin-dependent kinases regulate the antiproliferative function of Smads

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12 December 2020

ATM signaling and genomic stability in response to DNA damage

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12 December 2020

A two-step mechanism for stem cell activation during hair regeneration

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12 December 2020