(Q39354039)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22555804%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

Novel small molecular inhibitors disrupt the JAK/STAT3 and FAK signaling pathways and exhibit a potent antitumor activity in glioma cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22555804%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

2

1 reference

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Aleksandra Ellert-Miklaszewska

31 January 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22555804%20AND%20SRC:MED&resulttype=core&format=json

Bożena Kamińska-Kaczmarek

31 January 2020

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22555804%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

9

Grzegorz Grynkiewicz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22555804%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

4

Piotr Swierk

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22555804%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

author name string

Karolina Swiatek-Machado

1

1 reference

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31 January 2020

Izabela Fokt

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22555804%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Slawomir Szymanski

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22555804%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Stanislaw Skora

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22555804%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Wiesław Szeja

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22555804%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Bogdan Lesyng

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22555804%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Waldemar Priebe

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22555804%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

publication date

1 June 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22555804%20AND%20SRC:MED&resulttype=core&format=json

Cancer Biology and Therapy

31 January 2020

published in

1 reference

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31 January 2020

volume

13

1 reference

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31 January 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22555804%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

page(s)

657-670

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22555804%20AND%20SRC:MED&resulttype=core&format=json

Roles of STAT3 defined by tissue-specific gene targeting

31 January 2020

cites work

1 reference

Constitutively activated STAT3 frequently coexpresses with epidermal growth factor receptor in high-grade gliomas and targeting STAT3 sensitizes them to Iressa and alkylators

21 January 2018

1 reference

JAK1 and Tyk2 activation by the homologous polycythemia vera JAK2 V617F mutation: cross-talk with IGF1 receptor.

21 January 2018

1 reference

Loss of protein inhibitors of activated STAT-3 expression in glioblastoma multiforme tumors: implications for STAT-3 activation and gene expression

21 January 2018

1 reference

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

21 January 2018

1 reference

Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

21 January 2018

1 reference

A novel inhibitor of the STAT3 pathway induces apoptosis in malignant glioma cells both in vitro and in vivo

21 January 2018

1 reference

Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells

21 January 2018

1 reference

Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells

21 January 2018

1 reference

Designer therapies for glioblastoma multiforme

21 January 2018

1 reference

Deregulation of a STAT3-interleukin 8 signaling pathway promotes human glioblastoma cell proliferation and invasiveness.

21 January 2018

1 reference

Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway

21 January 2018

1 reference

STAT3 regulation of glioblastoma pathogenesis.

21 January 2018

1 reference

Anti-apoptosis mechanisms in malignant gliomas.

21 January 2018

1 reference

Focal adhesion kinase: a regulator of focal adhesion dynamics and cell movement

21 January 2018

1 reference

Focal adhesion kinase: in command and control of cell motility

21 January 2018

1 reference

Blockage of the STAT3 signaling pathway with a decoy oligonucleotide suppresses growth of human malignant glioma cells

21 January 2018

1 reference

STAT proteins as novel targets for cancer drug discovery

21 January 2018

1 reference

Monomeric recombinant peptide aptamers are required for efficient intracellular uptake and target inhibition

21 January 2018

1 reference

Small molecular inhibitors of p-STAT3: novel agents for treatment of primary and metastatic CNS cancers

21 January 2018

1 reference

Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor

21 January 2018

1 reference

Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells

21 January 2018

1 reference

The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors

21 January 2018

1 reference

The role of focal-adhesion kinase in cancer - a new therapeutic opportunity

21 January 2018

1 reference

Signal transduction by focal adhesion kinase in cancer

21 January 2018

1 reference

Targeting focal adhesion kinase signaling in tumor growth and metastasis

21 January 2018

1 reference

Sensing the environment: a historical perspective on integrin signal transduction

21 January 2018

1 reference

MAPK signalling pathways as molecular targets for anti-inflammatory therapy--from molecular mechanisms to therapeutic benefits

21 January 2018

1 reference

A death-promoting role for extracellular signal-regulated kinase

21 January 2018

1 reference

Prolonged activation of ERK triggers glutamate-induced apoptosis of astrocytes: neuroprotective effect of FK506.

21 January 2018

1 reference

Clinging to life: cell to matrix adhesion and cell survival

21 January 2018

1 reference

Immunosuppressant FK506 affects multiple signaling pathways and modulates gene expression in astrocytes

21 January 2018

1 reference

Cannabinoids down-regulate PI3K/Akt and Erk signalling pathways and activate proapoptotic function of Bad protein.

21 January 2018

1 reference

Bioconductor: open software development for computational biology and bioinformatics

21 January 2018

1 reference

Simpleaffy: a BioConductor package for Affymetrix Quality Control and data analysis

21 January 2018

1 reference

Preprocessing of oligonucleotide array data

21 January 2018

1 reference

Probe set filtering increases correlation between Affymetrix GeneChip and qRT-PCR expression measurements

21 January 2018

1 reference

Statistical significance for genomewide studies

21 January 2018

1 reference

Using GOstats to test gene lists for GO term association

21 January 2018

1 reference