(Q39370899)

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TricycloDNA-modified oligo-2'-deoxyribonucleotides reduce scavenger receptor B1 mRNA in hepatic and extra-hepatic tissues--a comparative study of oligonucleotide length, design and chemistry.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22467214%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

TricycloDNA-modified oligo-2'-deoxyribonucleotides reduce scavenger receptor B1 mRNA in hepatic and extra-hepatic tissues--a comparative study of oligonucleotide length, design and chemistry (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22467214%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

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Christian J. Leumann

9

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22467214%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

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Sue Murray

1

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27 January 2020

Damian Ittig

2

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27 January 2020

Erich Koller

3

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27 January 2020

Andres Berdeja

4

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27 January 2020

Alfred Chappell

5

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27 January 2020

Thazha P Prakash

6

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27 January 2020

Michaela Norrbom

7

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27 January 2020

Eric E Swayze

8

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27 January 2020

Punit P Seth

10

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27 January 2020

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30 March 2012

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27 January 2020

Nucleic Acids Research

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22467214%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

40

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27 January 2020

13

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27 January 2020

6135-6143

1 reference

Europe PubMed Central

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27 January 2020

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Creative Commons Attribution-NonCommercial 3.0 Unported

4 October 2016

1 reference

April 2022 Public Data File from Crossref

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Synthesis, Improved Antisense Activity and Structural Rationale for the Divergent RNA Affinities of 3′-Fluoro Hexitol Nucleic Acid (FHNA and Ara-FHNA) Modified Oligonucleotides

1 reference

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11 September 2017

Mechanisms of single-stranded phosphorothioate modified antisense oligonucleotide accumulation in hepatocytes

1 reference

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11 September 2017

An Exocyclic Methylene Group Acts As a Bioisostere of the 2′-Oxygen Atom in LNA

1 reference

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RNAi and small interfering RNAs in human disease therapeutic applications

1 reference

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11 September 2017

Position-dependent effects on stability in tricyclo-DNA modified oligonucleotide duplexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401458

11 September 2017

Short locked nucleic acid antisense oligonucleotides potently reduce apolipoprotein B mRNA and serum cholesterol in mice and non-human primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401458

11 September 2017

Locked nucleic acids: promising nucleic acid analogs for therapeutic applications.

1 reference

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Synthesis and biophysical evaluation of 2',4'-constrained 2'O-methoxyethyl and 2',4'-constrained 2'O-ethyl nucleic acid analogues.

1 reference

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11 September 2017

Nucleic acids with a six-membered 'carbohydrate' mimic in the backbone

1 reference

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11 September 2017

RNA targeting therapeutics: molecular mechanisms of antisense oligonucleotides as a therapeutic platform

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401458

11 September 2017

LNA-mediated microRNA silencing in non-human primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401458

11 September 2017

2'-Modified oligonucleotides for antisense therapeutics

1 reference

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11 September 2017

Silencing of microRNAs in vivo with 'antagomirs'

1 reference

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11 September 2017

Nuclear antisense effects in cyclophilin A pre-mRNA splicing by oligonucleotides: a comparison of tricyclo-DNA with LNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401458

11 September 2017

Cell entry of hepatitis C virus requires a set of co-receptors that include the CD81 tetraspanin and the SR-B1 scavenger receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401458

11 September 2017

DNA analogues: from supramolecular principles to biological properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401458

11 September 2017

Pharmacokinetics of phosphorothioate antisense oligodeoxynucleotides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401458

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Mechanisms and applications of immune stimulatory CpG oligodeoxynucleotides

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Crystal structure and improved antisense properties of 2'-O-(2-methoxyethyl)-RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401458

11 September 2017

The ups and downs of nucleic acid duplex stability: structure-stability studies on chemically-modified DNA:RNA duplexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401458

11 September 2017

Identification of scavenger receptor SR-BI as a high density lipoprotein receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401458

11 September 2017

Antisense oligonucleotides containing conformationally constrained 2',4'-(N-methoxy)aminomethylene and 2',4'-aminooxymethylene and 2'-O,4'-C-aminomethylene bridged nucleoside analogues show improved potency in animal models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401458

14 September 2017

Short antisense oligonucleotides with novel 2'-4' conformationaly restricted nucleoside analogues show improved potency without increased toxicity in animals

1 reference

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14 September 2017

Host scavenger receptor SR-BI plays a dual role in the establishment of malaria parasite liver infection

1 reference

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Identification and characterization of second-generation antisense oligonucleotides

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Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial

1 reference

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1 reference

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Watson-Crick base-pairing properties of tricyclo-DNA.

1 reference

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21 August 2018

Evaluation of 2'-modified oligonucleotides containing 2'-deoxy gaps as antisense inhibitors of gene expression.

1 reference

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21 August 2018

Inhibition of protein kinase C-alpha expression in human A549 cells by antisense oligonucleotides inhibits induction of intercellular adhesion molecule 1 (ICAM-1) mRNA by phorbol esters.

1 reference

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21 August 2018

Configuration of the 5'-methyl group modulates the biophysical and biological properties of locked nucleic acid (LNA) oligonucleotides

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contributions of dangling end stacking and terminal base-pair formation to the stabilities of XGGCCp, XCCGGp, XGGCCYp, and XCCGGYp helixes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22467214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/NAR/GKS273

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22467214%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22467214%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

PubMed publication ID

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Europe PubMed Central

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27 January 2020

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