(Q39393226)

11 September 2017

title

Metabolic activation of diesel exhaust carcinogens in primary and immortalized human TP53 knock-in (Hupki) mouse embryo fibroblasts (English)

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11 September 2017

3

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11 September 2017

Jill E Kucab

1

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11 September 2017

David H Phillips

series ordinal

2

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11 September 2017

publication date

20 February 2012

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Environmental and Molecular Mutagenesis

11 September 2017

published in

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11 September 2017

volume

53

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11 September 2017

issue

3

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11 September 2017

page(s)

207-217

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3-Nitrobenzanthrone, a potential human cancer hazard in diesel exhaust and urban air pollution: a review of the evidence.

11 September 2017

cites work

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Activation of 3-nitrobenzanthrone and its metabolites to DNA-damaging species in human B lymphoblastoid MCL-5 cells

21 January 2018

1 reference

Metabolic activation of the environmental contaminant 3-nitrobenzanthrone by human acetyltransferases and sulfotransferase

21 January 2018

1 reference

3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone, forms DNA adducts after metabolic activation by human and rat liver microsomes: evidence for activation by cytochrome P450 1A1 and P450 1A2.

21 January 2018

1 reference

Identification of three major DNA adducts formed by the carcinogenic air pollutant 3-nitrobenzanthrone in rat lung at the C8 and N2 position of guanine and at the N6 position of adenine

21 January 2018

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Sequence-specific detection of aristolochic acid-DNA adducts in the human p53 gene by terminal transferase-dependent PCR.

21 January 2018

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Environmental pollutant and potent mutagen 3-nitrobenzanthrone forms DNA adducts after reduction by NAD(P)H:quinone oxidoreductase and conjugation by acetyltransferases and sulfotransferases in human hepatic cytosols

21 January 2018

1 reference

Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null mice.

21 January 2018

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Aristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer.

21 January 2018

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Gene expression changes induced by the human carcinogen aristolochic acid I in renal and hepatic tissue of mice

21 January 2018

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Applications of the human p53 knock-in (Hupki) mouse model for human carcinogen testing.

21 January 2018

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Loss of DNA repair capacity during successive subcultures of primary rat fibroblasts

21 January 2018

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The comet assay: topical issues.

21 January 2018

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Identification of 5-(deoxyguanosin-N2-yl)- 1,2-dihydroxy-1,2-dihydro-6-aminochrysene as the major DNA lesion in the mammary gland of rats treated with the environmental pollutant 6-nitrochrysene

21 January 2018

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Inactivation of the hepatic cytochrome P450 system by conditional deletion of hepatic cytochrome P450 reductase.

21 January 2018

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Time- and concentration-dependent changes in gene expression induced by benzo(a)pyrene in two human cell lines, MCF-7 and HepG2.

21 January 2018

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p53 mutations in human cancers

21 January 2018

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Linking environmental carcinogen exposure to TP53 mutations in human tumours using the human TP53 knock-in (Hupki) mouse model.

21 January 2018

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Effects of nitrated-polycyclic aromatic hydrocarbons and diesel exhaust particle extracts on cell signalling related to apoptosis: possible implications for their mutagenic and carcinogenic effects.

21 January 2018

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Human tumor p53 mutations are selected for in mouse embryonic fibroblasts harboring a humanized p53 gene

21 January 2018

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Knock-in mice with a chimeric human/murine p53 gene develop normally and show wild-type p53 responses to DNA damaging agents: a new biomedical research tool.

21 January 2018

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DNA adduct formation and mutation induction by aristolochic acid in rat kidney and liver.

21 January 2018

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Heterologous expression of human N-acetyltransferases 1 and 2 and sulfotransferase 1A1 in Salmonella typhimurium for mutagenicity testing of heterocyclic amines

21 January 2018

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TP53 mutation signature supports involvement of aristolochic acid in the aetiology of endemic nephropathy-associated tumours

21 January 2018

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Contribution of NAD(P)H:quinone oxidoreductase 1 to protection against carcinogenesis, and regulation of its gene by the Nrf2 basic-region leucine zipper and the arylhydrocarbon receptor basic helix-loop-helix transcription factors

21 January 2018

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Differential effects of nitro-PAHs and amino-PAHs on cytokine and chemokine responses in human bronchial epithelial BEAS-2B cells

21 January 2018

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Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

21 January 2018

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Mutagenicity of nitroaromatic compounds

21 January 2018

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Common tumour p53 mutations in immortalized cells from Hupki mice heterozygous at codon 72.

21 January 2018

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Mechanisms of the different DNA adduct forming potentials of the urban air pollutants 2-nitrobenzanthrone and carcinogenic 3-nitrobenzanthrone

21 January 2018

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Mutagenicity and carcinogenicity of nitroarenes and their sources in the environment

21 January 2018

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The presence of mutagens/carcinogens in the excised lung and analysis of lung cancer induction

21 January 2018

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The carcinogenic air pollutant 3-nitrobenzanthrone induces GC to TA transversion mutations in human p53 sequences.

21 January 2018

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MEF immortalization to investigate the ins and outs of mutagenesis

21 January 2018

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Aristolochic acid-induced carcinogenesis examined by ACB-PCR quantification of H-Ras and K-Ras mutant fraction.

21 January 2018

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Wild-type and Hupki (human p53 knock-in) murine embryonic fibroblasts: p53/ARF pathway disruption in spontaneous escape from senescence

21 January 2018

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Environmental exposure measurement in cancer epidemiology

21 January 2018

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Development of an in vitro primary screen for skin depigmentation and antimelanoma agents

21 January 2018

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7 January 2021

Mutagenesis of human p53 tumor suppressor gene sequences in embryonic fibroblasts of genetically-engineered mice.

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7 January 2021

Induction of biotransformation enzymes by the carcinogenic air-pollutant 3-nitrobenzanthrone in liver, kidney and lung, after intra-tracheal instillation in rats

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7 January 2021

The 32P-postlabeling assay for DNA adducts

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7 January 2021

Identifiers

DOI

10.1002/EM.21679

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11 September 2017

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