(Q39393558)

11 September 2017

Critical role of arachidonic acid-activated mTOR signaling in breast carcinogenesis and angiogenesis (English)

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11 September 2017

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Z-H Wen

1

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11 September 2017

Y-C Su

2

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11 September 2017

P-L Lai

3

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11 September 2017

Y Zhang

4

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11 September 2017

Y-F Xu

5

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11 September 2017

A Zhao

6

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11 September 2017

G-Y Yao

7

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11 September 2017

C-H Jia

8

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11 September 2017

J Lin

9

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11 September 2017

S Xu

10

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11 September 2017

L Wang

11

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11 September 2017

X-K Wang

12

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11 September 2017

A-L Liu

13

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11 September 2017

Y Jiang

14

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11 September 2017

Y-F Dai

15

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11 September 2017

X-C Bai

16

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11 September 2017

language of work or name

English

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publication date

20 February 2012

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11 September 2017

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11 September 2017

32

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2

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11 September 2017

160-170

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https://scigraph.springernature.com/pub.10.1038/onc.2012.47

11 September 2017

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cites work

Five-lipoxygenase pathway of arachidonic acid metabolism in carcino-genesis and cancer chemoprevention

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Targeting the eicosanoid pathway in non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Arachidonic-acid-derived eicosanoids: roles in biology and immunopathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Cytosolic phospholipase A(2), lipoxygenase metabolites, and reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Roles of cPLA2alpha and arachidonic acid in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Lipoxygenase inhibitors for cancer prevention: promises and risks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

NSAIDs and breast cancer: a possible prevention and treatment strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

The role of cyclooxygenase-2 in breast cancer: review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Non-steroidal anti-inflammatory drugs for cancer prevention: promise, perils and pharmacogenetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Aberrant expression of 5-lipoxygenase-activating protein (5-LOXAP) has prognostic and survival significance in patients with breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Nordihydroguaiaretic acid suppression of rat mammary carcinogenesis induced by N-methyl-N-nitrosourea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Arachidonic acid promotes FAK activation and migration in MDA-MB-231 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Requirement of Protein Kinase Cμ Activation and Calpain-mediated Proteolysis for Arachidonic Acid-stimulated Adhesion of MDA-MB-435 Human Mammary Carcinoma Cells to Collagen Type IV

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Key factors in mTOR regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

mTOR: from growth signal integration to cancer, diabetes and ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

mTOR and cancer: many loops in one pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Defining the role of mTOR in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Arachidonic acid promotes epithelial-to-mesenchymal-like transition in mammary epithelial cells MCF10A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Lipoxygenase metabolism: roles in tumor progression and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

The mTOR pathway in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Stimulatory effect of arachidonic acid on T-47D human breast cancer cell growth is associated with enhancement of cyclin D1 mRNA expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Fibroblast growth factor-2 is a downstream mediator of phosphatidylinositol 3-kinase-Akt signaling in 14,15-epoxyeicosatrienoic acid-induced angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

15(S)-hydroxyeicosatetraenoic acid induces angiogenesis via activation of PI3K-Akt-mTOR-S6K1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

mTOR links oncogenic signaling to tumor cell metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Tuberous sclerosis complex: linking cancer to metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

mTOR generates an auto-amplification loop by triggering the βTrCP- and CK1α-dependent degradation of DEPTOR

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Dietary intakes of omega-6 and omega-3 polyunsaturated fatty acids and the risk of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Overexpression of group II phospholipase A2 in human breast cancer tissues is closely associated with their malignant potency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Dual inhibition of 5-LOX and COX-2 suppresses colon cancer formation promoted by cigarette smoke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Arachidonic acid activates mitogen-activated protein (MAP) kinase-activated protein kinase 2 and mediates adhesion of a human breast carcinoma cell line to collagen type IV through a p38 MAP kinase-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Oleic acid promotes migration on MDA-MB-231 breast cancer cells through an arachidonic acid-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Inhibition of arachidonic acid metabolism and its implication on cell proliferation and tumour-angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Cytosolic phospholipase A2 and lysophospholipids in tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Decreased lung tumorigenesis in mice genetically deficient in cytosolic phospholipase A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Depletion of cytosolic phospholipase A2 in bone marrow-derived macrophages protects against lung cancer progression and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Prostaglandin E2 activates and utilizes mTORC2 as a central signaling locus for the regulation of mast cell chemotaxis and mediator release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Met expression is associated with poor outcome in patients with axillary lymph node negative breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Multi-mechanisms are involved in reactive oxygen species regulation of mTORC1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Rheb activates mTOR by antagonizing its endogenous inhibitor, FKBP38.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Association of Dietary Intake of Fat and Fatty Acids With Risk of Breast Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Endothelium-dependent contractions in rabbit pulmonary artery are mediated by thromboxane A2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

Quantitative role of plasma free fatty acids in the supply of arachidonic acid to extrahepatic tissues in rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.47

31 March 2020

Identifiers

DOI

10.1038/ONC.2012.47

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11 September 2017

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