(Q39395631)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22341439%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

TAK1 inhibition promotes apoptosis in KRAS-dependent colon cancers (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22341439%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22341439%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

7

Daniel A Haber

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22341439%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

5

Patricia Greninger

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22341439%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

author name string

Michael F Sweeney

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22341439%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Min Yu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22341439%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Alexa Burger

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22341439%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Cyril Benes

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22341439%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Jeff Settleman

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22341439%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

language of work or name

English

0 references

publication date

1 February 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22341439%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22341439%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

volume

148

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22341439%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22341439%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

page(s)

639-650

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22341439%20AND%20SRC:MED&resulttype=core&format=json

Receptor tyrosine kinases exert dominant control over PI3K signaling in human KRAS mutant colorectal cancers

23 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

Modulation of pancreatic cancer chemoresistance by inhibition of TAK1

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

Lentiviral vectors to probe and manipulate the Wnt signaling pathway

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

A versatile viral system for expression and depletion of proteins in mammalian cells

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

Implications for KRAS status and EGFR-targeted therapies in metastatic CRC.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

A two-step model for colon adenoma initiation and progression caused by APC loss

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

Principles of cancer therapy: oncogene and non-oncogene addiction

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

The pseudoreceptor BMP and activin membrane-bound inhibitor positively modulates Wnt/beta-catenin signaling

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

A pivotal role for endogenous TGF-beta-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

Wnt signaling drives WRM-1/beta-catenin asymmetries in early C. elegans embryos

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

DAVID: Database for Annotation, Visualization, and Integrated Discovery

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

Targeting RAS signalling pathways in cancer therapy

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

Exploring the conditional coregulation of yeast gene expression through fuzzy k-means clustering

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

Inhibition of endotoxin-induced TNF-alpha production in macrophages by 5Z-7-oxo-zeaenol and other fungal resorcylic acid lactones

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

MOM-4, a MAP kinase kinase kinase-related protein, activates WRM-1/LIT-1 kinase to transduce anterior/posterior polarity signals in C. elegans

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

Cluster analysis and display of genome-wide expression patterns

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

K- and N-Ras are geranylgeranylated in cells treated with farnesyl protein transferase inhibitors

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

Functional interaction of beta-catenin with the transcription factor LEF-1

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

Genetic alterations during colorectal-tumor development

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

Transcription factor PROX1 induces colon cancer progression by promoting the transition from benign to highly dysplastic phenotype

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

Integrative approach for prioritizing cancer genes in sporadic colon cancer.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291475

The evolving war on cancer

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22341439

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2011.12.033

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22341439%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22341439%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

PubMed publication ID

22341439

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22341439%20AND%20SRC:MED&resulttype=core&format=json