(Q39401678)

11 September 2017

1 reference

title

Physiology and pathophysiology of the plasminogen system in the kidney (English)

1 reference

11 September 2017

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28656379%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Gitte Rye Hinrichs

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28656379%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

author name string

Rikke Zachar

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28656379%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Rikke Ydegaard

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28656379%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Boye L Jensen

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28656379%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

publication date

27 June 2017

1 reference

11 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28656379%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

volume

469

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28656379%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28656379%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

page(s)

1415-1423

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28656379%20AND%20SRC:MED&resulttype=core&format=json

Diabetic nephropathy is associated with increased urine excretion of proteases plasmin, prostasin and urokinase and activation of amiloride-sensitive current in collecting duct cells.

2 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Remission of nephrotic syndrome diminishes urinary plasmin content and abolishes activation of ENaC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Proteomics-based discovery of a novel, structurally unique, and developmentally regulated plasminogen receptor, Plg-RKT, a major regulator of cell surface plasminogen activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Association of genetic variants of fibrinolytic system with stroke and stroke subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Increased plasminogen activator (urokinase) in tissue culture after fibrin deposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Plasminogen activators and plasminogen activator inhibitors in gingival crevicular fluid of cyclosporin A-treated patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Urinary plasmin activates collecting duct ENaC current in preeclampsia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Plasminogen activator inhibitor-1 (PAI-1): a key factor linking fibrinolysis and age-related subclinical and clinical conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Regulation of epithelial sodium channels in urokinase plasminogen activator deficiency

21 January 2018

1 reference

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A novel form of the plasminogen activator inhibitor created by cysteine mutations extends its half-life: relevance to cancer and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Plasminogen activator inhibitor-1: a common denominator in obesity, diabetes and cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

The urokinase-type-plasminogen-activator receptor (CD87) is a pleiotropic molecule

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

The urokinase receptor system, a key regulator at the intersection between inflammation, immunity, and coagulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Molecular mechanism of edema formation in nephrotic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Plasminogen activator inhibitor-1 in chronic kidney disease: evidence and mechanisms of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Plasmin is not protective in experimental renal interstitial fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Low-renin status in therapy-resistant hypertension: a clue to efficient treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Circulating soluble urokinase plasminogen activator receptor predicts cancer, cardiovascular disease, diabetes and mortality in the general population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

21 January 2018

PAI-1 in tissue fibrosis

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Plasminogen receptors and their role in the pathogenesis of inflammatory, autoimmune and malignant disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Renal urokinase-type plasminogen activator (uPA) receptor but not uPA deficiency strongly attenuates ischemia reperfusion injury and acute kidney allograft rejection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Urokinase-derived peptides regulate vascular smooth muscle contraction in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Active proteases in nephrotic plasma lead to a podocin-dependent phosphorylation of VASP in podocytes via protease activated receptor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Soluble Urokinase Receptor and Chronic Kidney Disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Proteinase-activated receptors 1 and 2 exert opposite effects on renal renin release

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Reduction of mouse atherosclerosis by urokinase inhibition or with a limited-spectrum matrix metalloproteinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Proteolytic regulation of epithelial sodium channels by urokinase plasminogen activator: cutting edge and cleavage sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Plasminogen activator inhibitor-1 deficiency prevents hypertension and vascular fibrosis in response to long-term nitric oxide synthase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Plasminogen and plasminogen activators protect against renal injury in crescentic glomerulonephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Podocyte injury-driven intracapillary plasminogen activator inhibitor type 1 accelerates podocyte loss via uPAR-mediated β1-integrin endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Plasminogen mediates the atherogenic effects of macrophage-expressed urokinase and accelerates atherosclerosis in apoE-knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Localization of urokinase-type plasminogen activator messenger RNA in the normal mouse by in situ hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Distribution of urokinase-type plasminogen activator immunoreactivity in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Type 1 plasminogen activator inhibitor and its potential influence on thrombolytic therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

PAI-1, fibrosis, and the elusive provisional fibrin matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Plasminogen activation independent of uPA and tPA maintains wound healing in gene-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Effect of plasminogen activator inhibitor-1 in diabetes mellitus and cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Mechanism of activation of latent recombinant transforming growth factor beta 1 by plasmin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Plasminogen activator inhibitor-1 in kidney pathology (Review).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

The kidney is a major site of alpha(2)-antiplasmin production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Binding of urokinase to low density lipoprotein-related receptor (LRP) regulates vascular smooth muscle cell contraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Proteomic characterization of serine hydrolase activity and composition in normal urine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Plasminogen activator inhibitor-1 deficiency retards diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Plasminogen activator inhibitor-1 and the circadian clock in metabolic disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Lack of both α2-antiplasmin and plasminogen activator inhibitor type-1 induces high IgE production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Plasmin activates epithelial Na+ channels by cleaving the gamma subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Renin angiotensin system blockade reduces urinary levels of soluble urokinase plasminogen activator receptor (suPAR) in patients with type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Urokinase (u-PA) is produced by collecting duct principal cells and is post-transcriptionally regulated by SV40 large-T, arginine vasopressin, and epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Plasminogen deficiency leads to impaired lobular reorganization and matrix accumulation after chronic liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Urokinase receptor: a molecular organizer in cellular communication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Podocyte injury: the role of proteinuria, urinary plasminogen, and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Synthesis of human plasminogen by the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Expression of urokinase plasminogen activator and its receptor during acute renal allograft rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Urokinase synthesis and binding by glomerular epithelial cells in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Cell-matrix adhesion of podocytes in physiology and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Improvement in blood pressure with inhibition of the epithelial sodium channel in blacks with hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Sites of synthesis of urokinase and tissue-type plasminogen activators in the murine kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Effect of combined AT1 receptor and aldosterone receptor antagonism on plasminogen activator inhibitor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

PAI-1 and diabetes: a journey from the bench to the bedside

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

The podocyte's response to injury: role in proteinuria and glomerulosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Differential expression of the urokinase receptor in fibroblasts from normal and fibrotic human lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Serum-soluble urokinase receptor levels do not distinguish focal segmental glomerulosclerosis from other causes of nephrotic syndrome in children.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Regulation of cell signalling by uPAR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Plasmin in nephrotic urine activates the epithelial sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Prostasin-dependent activation of epithelial Na+ channels by low plasmin concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

The development of bleomycin-induced pulmonary fibrosis in mice deficient for components of the fibrinolytic system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Soluble urokinase plasminogen activator receptor levels are elevated and associated with complications in patients with type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

suPAR: the molecular crystal ball

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Urinary plasmin inhibits TRPV5 in nephrotic-range proteinuria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

An epithelial serine protease activates the amiloride-sensitive sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Amiloride selectively inhibits the urokinase-type plasminogen activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

The plasminogen activator/plasmin system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Modification of kidney barrier function by the urokinase receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Plasminogen activator inhibitor-1 4G/5G polymorphism and risk of stroke: replicated findings in two nested case-control studies based on independent cohorts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Different expression of the plasminogen activation system in renal thrombotic microangiopathy and the normal human kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Urokinase receptor deficiency accelerates renal fibrosis in obstructive nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Urinary Proteolytic Activation of Renal Epithelial Na+ Channels in Chronic Heart Failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

The contribution of chronic kidney disease to the global burden of major noncommunicable diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

PAI-1 deficiency attenuates the fibrogenic response to ureteral obstruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Plasmin(ogen) Promotes Renal Interstitial Fibrosis by Promoting Epithelial-to-Mesenchymal Transition: Role of Plasmin-Activated Signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

Plasminogen activator inhibitor-1 deficiency has renal benefits but some adverse systemic consequences in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-017-2014-Y

ECM degradation by cultured human mesangial cells is mediated by a PA/plasmin/MMP-2 cascade

21 January 2018

1 reference

12 December 2020

Significant natriuretic and antihypertensive action of the epithelial sodium channel blocker amiloride in diabetic patients with and without nephropathy

1 reference

12 December 2020

Central role for sodium in the pathogenesis of blood pressure changes independent of angiotensin, aldosterone and catecholamines in type 1 (insulin-dependent) diabetes mellitus

1 reference

12 December 2020

The biological significance of fibrinolysis

1 reference

12 December 2020

Fibrinolytic gene polymorphism and ischemic stroke

1 reference

12 December 2020

Sites of urokinase-type plasminogen activator expression and distribution of its receptor in the normal human kidney

1 reference

12 December 2020

Plasmin in urine from patients with type 2 diabetes and treatment-resistant hypertension activates ENaC in vitro

1 reference

12 December 2020

Alpha2-antiplasmin gene deficiency in mice is associated with enhanced fibrinolytic potential without overt bleeding.

1 reference

12 December 2020

Aberrant glomerular filtration of urokinase-type plasminogen activator in nephrotic syndrome leads to amiloride-sensitive plasminogen activation in urine

1 reference

12 December 2020

The haemostatic balance

1 reference

12 December 2020

Distribution of plasminogen activators in human kidney and male genital organs using a highly sensitive enzyme immunoassay

1 reference

12 December 2020

Endotoxin stimulates expression of the murine urokinase receptor gene in vivo

1 reference

12 December 2020

A proenzyme form of human urokinase

1 reference

12 December 2020

[The study of plasminogen activator in renal cell carcinoma with special remarks on urokinase type plasminogen activator]

1 reference

12 December 2020

Role of angiotensin and the clock system in the circadian regulation of plasminogen activator inhibitor-1

1 reference

12 December 2020

Rapid isolation of high molecular weight urokinase from native human urine

1 reference

12 December 2020

The receptor-binding sequence of urokinase. A biological function for the growth-factor module of proteases

1 reference

12 December 2020

Plasminogen activator from human embryonic kidney cell cultures. Evidence for a proactivator

1 reference

12 December 2020

Chronic allograft nephropathy: expression and localization of PAI-1 and PPAR-gamma

1 reference

12 December 2020

The peptide chains of human plasmin. Mechanism of activation of human plasminogen to plasmin

1 reference

12 December 2020

Human urokinase receptor expression is inhibited by amiloride and induced by tumor necrosis factor and phorbol ester in colon cancer cells

1 reference

12 December 2020

Extracellular matrix remodeling by metalloproteinases and plasminogen activators

1 reference

12 December 2020

Enhanced fibrinolytic potential in mice with combined homozygous deficiency of alpha2-antiplasmin and PAI-1

1 reference

12 December 2020

Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis

1 reference

12 December 2020

Activation of plasminogen by pro-urokinase. I. Mechanism

1 reference

12 December 2020

Plasminogen activator inhibitors

1 reference

12 December 2020

Studies on the purification and characterization of human urinary plasminogen and plasmin

1 reference

12 December 2020

Major circadian fluctuations in fibrinolytic factors and possible relevance to time of onset of myocardial infarction, sudden cardiac death and stroke

1 reference

12 December 2020

Plasma levels and urinary excretion of fibrinolytic and protease inhibitory proteins in nephrotic syndrome

1 reference

12 December 2020

Angiotensin II receptor blockade ameliorates mesangioproliferative glomerulonephritis in rats through suppression of CTGF and PAI-1, independently of the coagulation system

1 reference

12 December 2020

Human plasminogen activator inhibitor-1 (PAI-1) deficiency: characterization of a large kindred with a null mutation in the PAI-1 gene

1 reference

12 December 2020

Amiloride off-target effect inhibits podocyte urokinase receptor expression and reduces proteinuria

1 reference

12 December 2020

Plasminogen activator inhibitor-1 polymorphism is associated with progressive renal dysfunction after acute rejection in renal transplant recipients

1 reference

12 December 2020

Urokinase plasminogen activator cleaves its cell surface receptor releasing the ligand-binding domain

1 reference

12 December 2020

Receptor binding and degradation of urokinase-type plasminogen activator by human mesangial cells

1 reference

12 December 2020

Structural relationship between human high and low molecular mass urokinase

1 reference

12 December 2020

The human receptor for urokinase plasminogen activator. NH2-terminal amino acid sequence and glycosylation variants

1 reference

12 December 2020

Effect of antiproteolytic drugs: epsilon-aminocaproic acid (EACA) and aprotinin on experimental anti-GBM nephritis

1 reference

12 December 2020

Urinary fibrinolysis in toxemia of pregnancy

1 reference

12 December 2020

Plasminogen has a broad extrahepatic distribution

1 reference

12 December 2020

Cellular receptor for urokinase plasminogen activator. Carboxyl-terminal processing and membrane anchoring by glycosyl-phosphatidylinositol

1 reference

12 December 2020

Amiloride lowers blood pressure and attenuates urine plasminogen activation in patients with treatment–resistant hypertension

1 reference

12 December 2020

10.1007/S00424-017-2014-Y

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28656379%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference