(Q39407849)

English

The non-steroidal anti-inflammatory drug indomethacin activates the eIF2α kinase PKR, causing a translational block in human colorectal cancer cells

scientific article published on April 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

The non-steroidal anti-inflammatory drug indomethacin activates the eIF2α kinase PKR, causing a translational block in human colorectal cancer cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

0 references

colorectal cancer

1 reference

based on heuristic

inferred from title

colorectal carcinoma

1 reference

based on heuristic

inferred from title

author name string

Claudia Brunelli

1

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

Carla Amici

2

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

Mara Angelini

3

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

Chiara Fracassi

4

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

Giuseppe Belardo

5

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

M Gabriella Santoro

6

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

language of work or name

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publication date

1 April 2012

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

Biochemical Journal

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Europe PubMed Central

PubMed publication ID

11 September 2017

443

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

379-386

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

Activity of the non-steroidal anti-inflammatory drug indomethacin against colorectal cancer

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

The biological and therapeutic relevance of mRNA translation in cancer

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

Translational control in stress and apoptosis

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

The dsRNA protein kinase PKR: virus and cell control

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

Double-stranded RNA-dependent protein kinase phosphorylation of the alpha-subunit of eukaryotic translation initiation factor 2 mediates apoptosis

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): mechanism of action

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

PKR, apoptosis and cancer

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

Translational resistance of late alphavirus mRNA to eIF2alpha phosphorylation: a strategy to overcome the antiviral effect of protein kinase PKR.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

Targeting the heat shock factor 1 by RNA interference: a potent tool to enhance hyperthermochemotherapy efficacy in cervical cancer.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

Thiazolides, a new class of anti-influenza molecules targeting viral hemagglutinin at the post-translational level

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

Missense mutations associated with Diamond-Blackfan anemia affect the assembly of ribosomal protein S19 into the ribosome

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

Inhibition of nuclear factor kappa B by prostaglandin A1: an effect associated with heat shock transcription factor activation

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

Synergistic effect of indomethacin with adriamycin and cisplatin on tumor growth

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

The integrated stress response-associated signals modulates intestinal tumor cell growth by NSAID-activated gene 1 (NAG-1/MIC-1/PTGF-beta).

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

Dose translation from animal to human studies revisited

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

PKR and eIF2alpha: integration of kinase dimerization, activation, and substrate docking

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

Interferons induce tyrosine phosphorylation of the eIF2alpha kinase PKR through activation of Jak1 and Tyk2.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

PKR, a p53 target gene, plays a crucial role in the tumor-suppressor function of p53

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

Roles of the translationally controlled tumour protein (TCTP) and the double-stranded RNA-dependent protein kinase, PKR, in cellular stress responses.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

Nuclear factor-kappaB in cancer development and progression

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

The proapoptotic effects of sulindac, sulindac sulfone and indomethacin are mediated by nucleolar translocation of the RelA(p65) subunit of NF-kappaB.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

Sensitizing human colon carcinoma HT-29 cells to cisplatin by cyclopentenylcytosine, in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111236

21 January 2018

Identifiers

10.1042/BJ20111236

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

ResearchGate publication ID

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