(Q39411406)

11 September 2017

title

Notch1 signaling promotes survival of glioblastoma cells via EGFR-mediated induction of anti-apoptotic Mcl-1. (English)

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11 September 2017

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9

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11 September 2017

A Fassl

1

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11 September 2017

K E Tagscherer

2

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11 September 2017

J Richter

3

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11 September 2017

M Berriel Diaz

4

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11 September 2017

S R Alcantara Llaguno

5

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11 September 2017

B Campos

6

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11 September 2017

J Kopitz

7

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11 September 2017

C Herold-Mende

8

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11 September 2017

M H H Schmidt

10

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11 September 2017

L F Parada

11

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11 September 2017

O D Wiestler

12

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11 September 2017

W Roth

13

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11 September 2017

language of work or name

English

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publication date

16 January 2012

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11 September 2017

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11 September 2017

volume

31

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11 September 2017

issue

44

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11 September 2017

page(s)

4698-4708

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https://scigraph.springernature.com/pub.10.1038/onc.2011.615

11 September 2017

exact match

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cites work

Notch signaling: cell fate control and signal integration in development

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

The canonical Notch signaling pathway: unfolding the activation mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Contribution of Notch signaling activation to human glioblastoma multiforme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Notch activation promotes cell proliferation and the formation of neural stem cell-like colonies in human glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

The oncogenic roles of Notch1 in astrocytic gliomas in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Notch promotes survival of neural precursor cells via mechanisms distinct from those regulating neurogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Notch inhibits apoptosis by direct interference with XIAP ubiquitination and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Mitochondrial DNA integrity is essential for mitochondrial maturation during differentiation of neural stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Identification of human brain tumour initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Neural stem cells and the origin of gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.615

Differentiation therapy exerts antitumor effects on stem-like glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Metalloprotease ADAM10 is required for Notch1 site 2 cleavage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Mcl-1; the molecular regulation of protein function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Specific cleavage of Mcl-1 by caspase-3 in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in Jurkat leukemia T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Phosphorylation and inactivation of myeloid cell leukemia 1 by JNK in response to oxidative stress

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.615

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Epidermal growth factor (EGF) suppresses staurosporine-induced apoptosis by inducing mcl-1 via the mitogen-activated protein kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Notch-1 regulates transcription of the epidermal growth factor receptor through p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

ADAM17 regulates epidermal growth factor receptor expression through the activation of Notch1 in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Increased expression of Mcl-1 is responsible for the blockage of TRAIL-induced apoptosis mediated by EGF/ErbB1 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Apoptosis-based treatment of glioblastomas with ABT-737, a novel small molecule inhibitor of Bcl-2 family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Stem-cell-like glioma cells are resistant to TRAIL/Apo2L and exhibit down-regulation of caspase-8 by promoter methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Malignant astrocytic glioma: genetics, biology, and paths to treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Notch, neural stem cells, and brain tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Notch1 signaling promotes primary melanoma progression by activating mitogen-activated protein kinase/phosphatidylinositol 3-kinase-Akt pathways and up-regulating N-cadherin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Mcl-1 is a key regulator of apoptosis during CNS development and after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Mcl-1 degradation during hepatocyte lipoapoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

The regulatory domain of protein kinase Ctheta localises to the Golgi complex and induces apoptosis in neuroblastoma and Jurkat cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Different angiogenic phenotypes in primary and secondary glioblastomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Survival signaling by Notch1: mammalian target of rapamycin (mTOR)-dependent inhibition of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Arbiter of differentiation and death: Notch signaling meets apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

Unraveling MCL-1 degradation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.615

31 March 2020

Identifiers

DOI

10.1038/ONC.2011.615

1 reference

11 September 2017

1 reference