(Q33900952)

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A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 July 2017

A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

RNA interference

1 reference

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author name string

Zhi Sheng

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Li Li

2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Lihua J Zhu

3

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Thomas W Smith

4

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Andrea Demers

5

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Alonzo H Ross

6

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Richard P Moser

7

1 reference

Europe PubMed Central

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29 July 2017

Michael R Green

8

1 reference

Europe PubMed Central

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29 July 2017

language of work or name

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publication date

23 May 2010

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Europe PubMed Central

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29 July 2017

Nature Medicine

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Europe PubMed Central

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29 July 2017

16

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Europe PubMed Central

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29 July 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

671-677

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Breast cancer resistance protein and P-glycoprotein limit sorafenib brain accumulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

Interaction of the multikinase inhibitors sorafenib and sunitinib with solute carriers and ATP-binding cassette transporters

1 reference

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5 July 2018

Emerging Raf inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

Temozolomide in malignant gliomas: current use and future targets

1 reference

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5 July 2018

The FRS2 family of docking/scaffolding adaptor proteins as therapeutic targets of cancer treatment

1 reference

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5 July 2018

Principles of cancer therapy: oncogene and non-oncogene addiction

1 reference

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5 July 2018

Transcription and signalling pathways involved in BCR-ABL-mediated misregulation of 24p3 and 24p3R

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

The transcription factor ATF5: role in neurodevelopment and neural tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

EGFRvIII expression and PTEN loss synergistically induce chromosomal instability and glial tumors

1 reference

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5 July 2018

An integrated genomic analysis of human glioblastoma multiforme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

Recognizing and exploiting differences between RNAi and small-molecule inhibitors

1 reference

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5 July 2018

Phosphorylated Pak1 level in the cytoplasm correlates with shorter survival time in patients with glioblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

An elaborate pathway required for Ras-mediated epigenetic silencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

The kinase inhibitor sorafenib induces cell death through a process involving induction of endoplasmic reticulum stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

Oncomine 3.0: genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

The transcription factor ATF5 is widely expressed in carcinomas, and interference with its function selectively kills neoplastic, but not nontransformed, breast cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

p21-activated kinases in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

Recent advances in the molecular genetics of malignant gliomas disclose targets for antitumor agent perillyl alcohol

1 reference

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5 July 2018

Second-generation shRNA libraries covering the mouse and human genomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

Selective destruction of glioblastoma cells by interference with the activity or expression of ATF5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

Identification of a selective ERK inhibitor and structural determination of the inhibitor-ERK2 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

Apoptosis induced by the kinase inhibitor BAY 43-9006 in human leukemia cells involves down-regulation of Mcl-1 through inhibition of translation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

The role of Mcl-1 downregulation in the proapoptotic activity of the multikinase inhibitor BAY 43-9006.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

Phase I safety and pharmacokinetics of BAY 43-9006 administered for 21 days on/7 days off in patients with advanced, refractory solid tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

Phase I clinical and pharmacokinetic study of the Novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

The role of ATF/CREB family members in cell growth, survival and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

BAY 43-9006: preclinical data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

Function and regulation of CREB family transcription factors in the nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

Inhibition of apoptosis by ATFx: a novel role for a member of the ATF/CREB family of mammalian bZIP transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

The Hallmarks of Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

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Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

5 July 2018

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

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Identification of Ras farnesyltransferase inhibitors by microbial screening

1 reference

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A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

1 reference

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SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

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Liquid chromatography-tandem mass spectrometric assay for sorafenib and sorafenib-glucuronide in mouse plasma and liver homogenate and identification of the glucuronide metabolite

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

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1 reference

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29 October 2018

A different view on DNA amplifications indicates frequent, highly complex, and stable amplicons on 12q13-21 in glioma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

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Prognostic associations of activated mitogen-activated protein kinase and Akt pathways in glioblastoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

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Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

29 October 2018

Results of a Phase I trial of sorafenib (BAY 43-9006) in combination with doxorubicin in patients with refractory solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882506

29 October 2018

Safety and pharmacokinetics of the dual action Raf kinase and vascular endothelial growth factor receptor inhibitor, BAY 43-9006, in patients with advanced, refractory solid tumors

1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/20495567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The unequal variance t-test is an underused alternative to Student's t-test and the Mann–Whitney U test

1 reference

https://api.crossref.org/works/10.1038%2FNM.2158

7 January 2021

based on heuristic

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10.1038/NM.2158

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Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

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Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

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Europe PubMed Central

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29 July 2017

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