(Q39414202)

English

Chronic treatment with a glucokinase activator delays the onset of hyperglycaemia and preserves beta cell mass in the Zucker diabetic fatty rat.

scientific article published on 11 January 2012

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scholarly article

1 reference

Europe PubMed Central

11 September 2017

Chronic treatment with a glucokinase activator delays the onset of hyperglycaemia and preserves beta cell mass in the Zucker diabetic fatty rat. (English)

1 reference

Europe PubMed Central

11 September 2017

1 reference

based on heuristic

inferred from title

author name string

M Futamura

1

1 reference

Europe PubMed Central

11 September 2017

J Yao

2

1 reference

Europe PubMed Central

11 September 2017

X Li

3

1 reference

Europe PubMed Central

11 September 2017

R Bergeron

4

1 reference

Europe PubMed Central

11 September 2017

J-L Tran

5

1 reference

Europe PubMed Central

11 September 2017

E Zycband

6

1 reference

Europe PubMed Central

11 September 2017

J Woods

7

1 reference

Europe PubMed Central

11 September 2017

Y Zhu

8

1 reference

Europe PubMed Central

11 September 2017

Q Shao

9

1 reference

Europe PubMed Central

11 September 2017

H Maruki-Uchida

10

1 reference

Europe PubMed Central

11 September 2017

H Goto-Shimazaki

11

1 reference

Europe PubMed Central

11 September 2017

R B Langdon

12

1 reference

Europe PubMed Central

11 September 2017

M D Erion

13

1 reference

Europe PubMed Central

11 September 2017

J Eiki

14

1 reference

Europe PubMed Central

11 September 2017

Y-P Zhou

15

1 reference

Europe PubMed Central

11 September 2017

publication date

11 January 2012

1 reference

Europe PubMed Central

11 September 2017

1 reference

Europe PubMed Central

11 September 2017

55

1 reference

Europe PubMed Central

11 September 2017

4

1 reference

Europe PubMed Central

11 September 2017

1071-1080

1 reference

Europe PubMed Central

11 September 2017

https://scigraph.springernature.com/pub.10.1007/s00125-011-2439-3

0 references

Allosteric activators of glucokinase: potential role in diabetes therapy

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Impact of small-molecule glucokinase activator on glucose metabolism and beta-cell mass

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Assessing the potential of glucokinase activators in diabetes therapy

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Novel glucokinase activators: a patent review (2008 - 2010).

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Mutants of glucokinase cause hypoglycaemia- and hyperglycaemia syndromes and their analysis illuminates fundamental quantitative concepts of glucose homeostasis

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Severe persistent hyperinsulinemic hypoglycemia due to a de novo glucokinase mutation

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Update on mutations in glucokinase (GCK), which cause maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemic hypoglycemia

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Mutations in pancreatic ß-cell Glucokinase as a cause of hyperinsulinaemic hypoglycaemia and neonatal diabetes mellitus

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Large Islets, Beta-Cell Proliferation, and a Glucokinase Mutation

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Predictive blood glucose lowering efficacy by Glucokinase activators in high fat fed female Zucker rats

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

An allosteric activator of glucokinase impairs the interaction of glucokinase and glucokinase regulatory protein and regulates glucose metabolism

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Glucokinase activator PSN-GK1 displays enhanced antihyperglycaemic and insulinotropic actions

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

A small-molecule glucokinase activator lowers blood glucose in the sulfonylurea-desensitized rat.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Piragliatin (RO4389620), a novel glucokinase activator, lowers plasma glucose both in the postabsorptive state and after a glucose challenge in patients with type 2 diabetes mellitus: a mechanistic study

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Effects of MK-0941, a novel glucokinase activator, on glycemic control in insulin-treated patients with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Diabetes mellitus and genetically programmed defects in beta-cell function

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Type 2 diabetes-a matter of beta-cell life and death?

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Diabetes associated cell stress and dysfunction: role of mitochondrial and non-mitochondrial ROS production and activity

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Oxidative stress and beta-cell dysfunction

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Exposure to chronic high glucose induces beta-cell apoptosis through decreased interaction of glucokinase with mitochondria: downregulation of glucokinase in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Glucokinase and IRS-2 are required for compensatory beta cell hyperplasia in response to high-fat diet-induced insulin resistance.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Effects of glucokinase activators GKA50 and LY2121260 on proliferation and apoptosis in pancreatic INS-1 beta cells

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Current status of islet cell replacement and regeneration therapy

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Control of pancreatic β cell regeneration by glucose metabolism.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Prevention of glucose toxicity in HIT-T15 cells and Zucker diabetic fatty rats by antioxidants

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Diseases of liporegulation: new perspective on obesity and related disorders

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Structure-activity relationships of 3,5-disubstituted benzamides as glucokinase activators with potent in vivo efficacy.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Overexpression of repressive cAMP response element modulators in high glucose and fatty acid-treated rat islets. A common mechanism for glucose toxicity and lipotoxicity?

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

New sources of pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

The replication of beta cells in normal physiology, in disease and for therapy

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Insights into the critical role of NADPH oxidase(s) in the normal and dysregulated pancreatic beta cell

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Glucolipotoxicity: fuel excess and beta-cell dysfunction.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Tissue-specific disallowance of housekeeping genes: the other face of cell differentiation.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Pyruvate inhibits zinc-mediated pancreatic islet cell death and diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Investigation of functionally liver selective glucokinase activators for the treatment of type 2 diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

Selective β-Cell Loss and α-Cell Expansion in Patients with Type 2 Diabetes Mellitus in Korea

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2439-3

21 January 2018

The network of glucokinase-expressing cells in glucose homeostasis and the potential of glucokinase activators for diabetes therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22234649

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Islet amyloid, increased A-cells, reduced B-cells and exocrine fibrosis: quantitative changes in the pancreas in type 2 diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22234649

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitation of Endocrine Cell Content in the Pancreas of Nondiabetic and Diabetic Humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/22234649

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of epinephrine on rat diaphragm

1 reference

https://pubmed.ncbi.nlm.nih.gov/22234649

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/22234649

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-011-2439-3

1 reference

Europe PubMed Central

11 September 2017

1 reference

Europe PubMed Central

11 September 2017

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