(Q39414363)

11 September 2017

The N domain of Argonaute drives duplex unwinding during RISC assembly (English)

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11 September 2017

2

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11 September 2017

Pieter Bas Kwak

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11 September 2017

10 January 2012

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Nature Structural & Molecular Biology

11 September 2017

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11 September 2017

19

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11 September 2017

145-151

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11 September 2017

2

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https://scigraph.springernature.com/pub.10.1038/nsmb.2232

11 September 2017

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cites work

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Small silencing RNAs: an expanding universe

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Biogenesis of small RNAs in animals

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Argonaute2, a link between genetic and biochemical analyses of RNAi

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21 January 2018

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Multilayer checkpoints for microRNA authenticity during RISC assembly

21 January 2018

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The microRNA pathway and cancer

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Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

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Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation

21 January 2018

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Slicer function of Drosophila Argonautes and its involvement in RISC formation

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Cleavage of the siRNA passenger strand during RISC assembly in human cells

21 January 2018

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Structural determinants of miRNAs for RISC loading and slicer-independent unwinding

21 January 2018

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ATP-dependent human RISC assembly pathways

21 January 2018

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In vitro assembly of plant RNA-induced silencing complexes facilitated by molecular chaperone HSP90.

21 January 2018

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Hsc70/Hsp90 chaperone machinery mediates ATP-dependent RISC loading of small RNA duplexes

21 January 2018

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A direct role for Hsp90 in pre-RISC formation in Drosophila.

21 January 2018

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HSP90 protein stabilizes unloaded argonaute complexes and microscopic P-bodies in human cells

21 January 2018

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Asymmetry in the assembly of the RNAi enzyme complex

21 January 2018

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Functional siRNAs and miRNAs Exhibit Strand Bias

21 January 2018

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Crystal structure of Argonaute and its implications for RISC slicer activity

21 January 2018

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Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage

21 January 2018

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Structure of the guide-strand-containing argonaute silencing complex

21 January 2018

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Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein

21 January 2018

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Structural basis for 5'-nucleotide base-specific recognition of guide RNA by human AGO2

21 January 2018

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Crystal structure of the MID-PIWI lobe of a eukaryotic Argonaute protein

21 January 2018

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Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex

21 January 2018

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Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain

21 January 2018

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Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

21 January 2018

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Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes

21 January 2018

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Argonaute2 is the catalytic engine of mammalian RNAi

21 January 2018

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Phosphorylation of human Argonaute proteins affects small RNA binding.

21 January 2018

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C3PO, an endoribonuclease that promotes RNAi by facilitating RISC activation

21 January 2018

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Multimeric assembly and biochemical characterization of the Trax–translin endonuclease complex

21 January 2018

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Structure of C3PO and mechanism of human RISC activation

21 January 2018

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How to slice: snapshots of Argonaute in action

21 January 2018

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ATP requirements and small interfering RNA structure in the RNA interference pathway

21 January 2018

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Jalview Version 2--a multiple sequence alignment editor and analysis workbench

21 January 2018

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Clustal W and Clustal X version 2.0

21 January 2018

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Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

21 January 2018

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In vitro analysis of RNA interference in Drosophila melanogaster.

21 January 2018

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Native gel analysis for RISC assembly.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1038/NSMB.2232

1 reference

11 September 2017

1 reference

PubMed ID

22233755