(Q24336545)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19966796%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

ATP-dependent human RISC assembly pathways (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19966796%20AND%20SRC:MED&resulttype=core&format=json

double-stranded miRNA binding

13 February 2020

main subject

structural biology

0 references

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0098851

Argonaute RISC component 4

1 reference

Argonaute RISC component 1

1 reference

Argonaute RISC catalytic component 3

1 reference

Argonaute RISC catalytic component 2

1 reference

author

Shintaro Iwasaki

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19966796%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Yukihide Tomari

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19966796%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

author name string

Mayuko Yoda

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19966796%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Tomoko Kawamata

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19966796%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Zain Paroo

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19966796%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Xuecheng Ye

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19966796%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Qinghua Liu

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19966796%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

language of work or name

English

0 references

publication date

6 December 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19966796%20AND%20SRC:MED&resulttype=core&format=json

Nature Structural & Molecular Biology

13 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19966796%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19966796%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19966796%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

page(s)

17-23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19966796%20AND%20SRC:MED&resulttype=core&format=json

Small silencing RNAs: an expanding universe

13 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

In vitro reconstitution of the human RISC-loading complex

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Cleavage of the siRNA passenger strand during RISC assembly in human cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

A human, ATP-independent, RISC assembly machine fueled by pre-miRNA

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Identification of novel argonaute-associated proteins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Origins and Mechanisms of miRNAs and siRNAs

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Argonaute2 is the catalytic engine of mammalian RNAi

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Functional siRNAs and miRNAs Exhibit Strand Bias

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Asymmetry in the assembly of the RNAi enzyme complex

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Human RISC couples microRNA biogenesis and posttranscriptional gene silencing

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Purified Argonaute2 and an siRNA form recombinant human RISC

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Argonaute proteins: key players in RNA silencing

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Perspective: machines for RNAi

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

ATP requirements and small interfering RNA structure in the RNA interference pathway

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

The GW182 protein family in animal cells: new insights into domains required for miRNA-mediated gene silencing

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Drosophila argonaute1 and argonaute2 employ distinct mechanisms for translational repression.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Essential and overlapping functions for mammalian Argonautes in microRNA silencing

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

On the road to reading the RNA-interference code

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Two molecular features contribute to the Argonaute specificity for the microRNA and RNAi pathways in C. elegans

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

The mechanism selecting the guide strand from small RNA duplexes is different among argonaute proteins.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Specificity of ARGONAUTE7-miR390 interaction and dual functionality in TAS3 trans-acting siRNA formation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Sorting of small RNAs into Arabidopsis argonaute complexes is directed by the 5' terminal nucleotide

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Sorting of Drosophila small silencing RNAs

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Drosophila microRNAs are sorted into functionally distinct argonaute complexes after production by dicer-1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Short interfering RNA strand selection is independent of dsRNA processing polarity during RNAi in Drosophila

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Slicer function of Drosophila Argonautes and its involvement in RISC formation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Characterization of Dicer-deficient murine embryonic stem cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

A protein sensor for siRNA asymmetry

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

RISC assembly defects in the Drosophila RNAi mutant armitage.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915567

Structural determinants of miRNAs for RISC loading and slicer-independent unwinding

27 September 2017

1 reference

A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila

21 January 2018

1 reference

In vitro analysis of RNA interference in Drosophila melanogaster.

21 January 2018

1 reference

Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.

21 January 2018

1 reference

Structural features of small RNA precursors determine Argonaute loading in Caenorhabditis elegans

21 January 2018

1 reference

THE STABILITY CONSTANTS OF METAL-ADENINE NUCLEOTIDE COMPLEXES

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB.1733

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19966796%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

13 February 2020

1045972025

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19966796%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

19966796

2 references