(Q39414766)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22231444%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

RUNX3-mediated transcriptional inhibition of Akt suppresses tumorigenesis of human gastric cancer cells (English)

1 reference

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20 January 2020

12

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20 January 2020

author name string

F-C Lin

1

1 reference

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20 January 2020

Y-P Liu

2

1 reference

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20 January 2020

C-H Lai

3

1 reference

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20 January 2020

Y-S Shan

4

1 reference

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20 January 2020

H-C Cheng

5

1 reference

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20 January 2020

P-I Hsu

6

1 reference

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20 January 2020

C-H Lee

7

1 reference

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20 January 2020

Y-C Lee

8

1 reference

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20 January 2020

H-Y Wang

9

1 reference

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20 January 2020

C-H Wang

10

1 reference

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20 January 2020

J Q Cheng

11

1 reference

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20 January 2020

P-J Lu

13

1 reference

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20 January 2020

language of work or name

English

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publication date

9 January 2012

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20 January 2020

1 reference

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20 January 2020

volume

31

1 reference

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20 January 2020

issue

39

1 reference

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20 January 2020

page(s)

4302-4316

1 reference

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https://scigraph.springernature.com/pub.10.1038/onc.2011.596

20 January 2020

exact match

0 references

cites work

beta-catenin is a target for the ubiquitin-proteasome pathway

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

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Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis.

21 January 2018

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Claudin-1 has tumor suppressive activity and is a direct target of RUNX3 in gastric epithelial cells.

21 January 2018

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RUNX3 suppresses gastric epithelial cell growth by inducing p21(WAF1/Cip1) expression in cooperation with transforming growth factor {beta}-activated SMAD.

21 January 2018

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RUNX3 is multifunctional in carcinogenesis of multiple solid tumors

21 January 2018

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21 January 2018

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

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Patterning of cells in the Drosophila eye by Lozenge, which shares homologous domains with AML1.

21 January 2018

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Regulation of AKT1 expression by beta-catenin/Tcf/Lef signaling in colorectal cancer cells

21 January 2018

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Role of RUNX family members in transcriptional repression and gene silencing

21 January 2018

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Increased beta-catenin mRNA levels and mutational alterations of the APC and beta-catenin gene are present in intestinal-type gastric cancer.

21 January 2018

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Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers

21 January 2018

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Mutation and methylation of hMLH1 in gastric carcinomas with microsatellite instability

21 January 2018

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Runx3 controls growth and differentiation of gastric epithelial cells in mammals

21 January 2018

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Growth regulation of gastric epithelial cells by Runx3.

21 January 2018

1 reference

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Tumor suppressor gene Runx3 sensitizes gastric cancer cells to chemotherapeutic drugs by downregulating Bcl-2, MDR-1 and MRP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.596

Loss of RUNX3 expression correlates with differentiation, nodal metastasis, and poor prognosis of gastric cancer.

21 January 2018

1 reference

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RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis

21 January 2018

1 reference

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1'-acetoxychavicol acetate is a novel nuclear factor kappaB inhibitor with significant activity against multiple myeloma in vitro and in vivo

21 January 2018

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Molecular basis of tissue-specific gene expression mediated by the runt domain transcription factor PEBP2/CBF.

21 January 2018

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21 January 2018

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RUNX genes in development and cancer: regulation of viral gene expression and the discovery of RUNX family genes

21 January 2018

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Transforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradation

21 January 2018

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The Drosophila segmentation gene runt encodes a novel nuclear regulatory protein that is also expressed in the developing nervous system

21 January 2018

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Jab1/CSN5 induces the cytoplasmic localization and degradation of RUNX3.

21 January 2018

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Occurrence of p53 gene abnormalities in gastric carcinoma tumors and cell lines

21 January 2018

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AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization

21 January 2018

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Causal relationship between the loss of RUNX3 expression and gastric cancer

21 January 2018

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Mutations of PIK3CA in gastric adenocarcinoma

21 January 2018

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21 January 2018

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21 January 2018

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Upregulation of AKT1 protein expression in forskolin-stimulated macrophage: evidence from ChIP analysis that CREB binds to and activates the AKT1 promoter

21 January 2018

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21 January 2018

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Akt phosphorylation associates with LOH of PTEN and leads to chemoresistance for gastric cancer

21 January 2018

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PI3K-Akt pathway: its functions and alterations in human cancer

21 January 2018

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Upstream and downstream targets of RUNX proteins.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.596

Molecular cloning and characterization of the human AKT1 promoter uncovers its up-regulation by the Src/Stat3 pathway

21 January 2018

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21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.596

Helicobacter pylori infection and the risk of gastric carcinoma

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.596

RUNX3 inhibits the expression of vascular endothelial growth factor and reduces the angiogenesis, growth, and metastasis of human gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.596

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

Focus on gastric cancer.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.596

Genetic alterations in gastric cancer: relation to histological subtypes, tumor stage, and Helicobacter pylori infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.596

Involvement of MAPK and PI3K signaling pathway in sterigmatocystin-induced G2 phase arrest in human gastric epithelium cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.596

The RUNX3 tumor suppressor upregulates Bim in gastric epithelial cells undergoing transforming growth factor beta-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.596

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21 January 2018

1 reference

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21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.596

RUNX3, a novel tumor suppressor, is frequently inactivated in gastric cancer by protein mislocalization.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.596

Mutational analysis of AKT1, AKT2 and AKT3 genes in common human carcinomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.596

Helicobacter pylori and gastric cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.596

Loss of RUNX3 expression significantly affects the clinical outcome of gastric cancer patients and its restoration causes drastic suppression of tumor growth and metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.596

Aberrant methylation within RUNX3 CpG island associated with the nuclear and mitochondrial microsatellite instability in sporadic gastric cancers. Results of a GOIM (Gruppo Oncologico dell'Italia Meridionale) prospective study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.596

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/ONC.2011.596

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22231444%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference