(Q36178601)

12 August 2017

Mutation and methylation of hMLH1 in gastric carcinomas with microsatellite instability (English)

1 reference

12 August 2017

1 reference

Dian-Chun Fang

1

1 reference

12 August 2017

Rong-Quan Wang

2

1 reference

12 August 2017

Shi-Ming Yang

3

1 reference

12 August 2017

Jian-Ming Yang

4

1 reference

12 August 2017

Hai-Feng Liu

5

1 reference

12 August 2017

Gui-Yong Peng

6

1 reference

12 August 2017

Tian-Li Xiao

7

1 reference

12 August 2017

Yuan-Hui Luo

8

1 reference

12 August 2017

language of work or name

English

0 references

publication date

1 April 2003

1 reference

World Journal of Gastroenterology

12 August 2017

1 reference

12 August 2017

9

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12 August 2017

4

1 reference

12 August 2017

655-659

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DNA hypermethylation: when tumour suppressor genes go silent

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Treatment of cancer cells with methioninase produces DNA hypomethylation and increases DNA synthesis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

CpG methylation modifies the genetic stability of cloned repeat sequences

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Inverse relationship between APC gene mutation in gastric adenomas and development of adenocarcinoma

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Reactivating the expression of methylation silenced genes in human cancer

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

DNA methylation in cancer: too much, but also too little

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Genetic instability in human mismatch repair deficient cancers

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Report of 16 kindreds and one kindred with hMLH1 germline mutation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Methylation of hMLH1 promoter correlates with the gene silencing with a region-specific manner in colorectal cancer

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Hypermethylation of the hMLH1 gene promoter in solitary and multiple gastric cancers with microsatellite instability

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Clinicopathological and molecular genetic analysis of 4 typical Chinese HNPCC families.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Telomere erosion is independent of microsatellite instability but related to loss of heterozygosity in gastric cancer

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Microsatellite instability, MMR gene expression and proliferation kinetics in colorectal cancer with famillial predisposition

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Functional significance of concomitant inactivation of hMLH1 and hMSH6 in tumor cells of the microsatellite mutator phenotype.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings: parallel pathways of tumorigenesis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Infrequent loss of heterozygosity of APC/MCC and DCC genes in gastric cancer showing DNA microsatellite instability

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Molecular basis of HNPCC: mutations of MMR genes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Mismatch repair, genetic stability, and cancer

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Genetic alterations during colorectal-tumor development

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Characterization of six tumor suppressor genes and microsatellite instability in hepatocellular carcinoma in southern African blacks

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Clues to the pathogenesis of familial colorectal cancer

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

CpG island methylation in sporadic colorectal cancers and its relationship to microsatellite instability.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Microsatellite instability, loss of heterozygosity, and loss of hMLH1 and hMSH2 protein expression in endometrial carcinoma.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Differential involvement of the hypermethylator phenotype in hereditary and sporadic colorectal cancers with high-frequency microsatellite instability.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Extensive methylation of hMLH1 promoter region predominates in proximal colon cancer with microsatellite instability.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

High frequency of low-level microsatellite instability in early colorectal cancer.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

Hypermethylation of the hMLH1 gene promoter is associated with microsatellite instability in early human gastric neoplasia.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

MSI-L gastric carcinomas share the hMLH1 methylation status of MSI-H carcinomas but not their clinicopathological profile.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4611422

The Role of hMLH1 Methylation in the Development of Synchronous Sporadic Colorectal Carcinomas

23 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.3748%2FWJG.V9.I4.655

Genetic and epigenetic modification of mismatch repair genes hMSH2 and hMLH1 in sporadic breast cancer with microsatellite instability

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.3748%2FWJG.V9.I4.655

Evaluation of microsatellite instability and immunohistochemistry for the prediction of germ-line MSH2 and MLH1 mutations in hereditary nonpolyposis colon cancer families

21 January 2018

1 reference

12 December 2020

Methylation of the hMLH1 promoter but no hMLH1 mutations in sporadic gastric carcinomas with high-level microsatellite instability

1 reference

12 December 2020

Application of the National Cancer Institute international criteria for determination of microsatellite instability in ovarian cancer

1 reference

12 December 2020

DNA methylation and cancer

1 reference

12 December 2020

Low-level microsatellite instability occurs in most colorectal cancers and is a nonrandomly distributed quantitative trait

1 reference

12 December 2020

A genome-wide study of microsatellite instability in advanced gastric carcinoma

1 reference

12 December 2020

MSH2 andMLH1 mutations in sporadic replication error-positive colorectal carcinoma as assessed by two-dimensional DNA electrophoresis

1 reference

12 December 2020

Molecular characterization of undifferentiated-type gastric carcinoma

1 reference

12 December 2020

Microsatellite instability is a genetic marker for the development of multiple gastric cancers

1 reference

12 December 2020

Microsatellite alterations and target gene mutations in the early stages of multiple gastric cancer

1 reference

12 December 2020

Microsatellite instability and mismatch repair defects in cancer

1 reference

12 December 2020

Stromelysin-1 promoter mutations impair gelatinase B activation in high microsatellite instability sporadic colorectal tumors

1 reference

12 December 2020

Microsatellite instability and hereditary non-polyposis colon cancer

1 reference

12 December 2020

Identifiers

DOI

10.3748/WJG.V9.I4.655

1 reference

12 August 2017

1 reference

12 August 2017

1 reference