(Q39428367)

11 September 2017

title

Rapid synthesis of new DNMT inhibitors derivatives of procainamide (English)

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Dominique Guianvarc'h

13

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Olivier Lequin

9

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Thierry Drujon

5

object named as

Thierry Drujon

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Alexandre Ceccaldi

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Paola B Arimondo

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Catherine Sénamaud-Beaufort

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3

object named as

Catherine Sénamaud-Beaufort

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8

Renata Jurkowska

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Ludovic Halby

1

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Christine Champion

2

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Sophie Ajjan

4

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William G Nelson

10

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Alain Guy

11

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Clotilde Ferroud

14

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publication date

14 December 2011

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volume

13

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11 September 2017

issue

1

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11 September 2017

page(s)

157-165

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CpG islands--'a rough guide'.

11 September 2017

cites work

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An operational definition of epigenetics

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Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome

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Mammalian DNA methyltransferases: a structural perspective

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EUKARYOTIC CYTOSINE METHYLTRANSFERASES

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Molecular enzymology of mammalian DNA methyltransferases

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Epigenetics in cancer

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Epigenetics in cancer

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Anticancer drug discovery targeting DNA hypermethylation

21 January 2018

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Epi-drugs to fight cancer: from chemistry to cancer treatment, the road ahead

21 January 2018

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Epigenetics, DNA methylation, and chromatin modifying drugs

21 January 2018

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Epigenetic therapy of cancer: past, present and future

21 January 2018

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https://api.crossref.org/works/10.1002%2FCBIC.201100522

Procainamide is a specific inhibitor of DNA methyltransferase 1.

21 January 2018

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https://api.crossref.org/works/10.1002%2FCBIC.201100522

Constrained analogues of procaine as novel small molecule inhibitors of DNA methyltransferase-1.

21 January 2018

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Directing topoisomerase I mediated DNA cleavage to specific sites by camptothecin tethered to minor- and major-groove ligands

21 January 2018

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Design and optimization of camptothecin conjugates of triple helix-forming oligonucleotides for sequence-specific DNA cleavage by topoisomerase I.

21 January 2018

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Molecular basis of the targeting of topoisomerase II-mediated DNA cleavage by VP16 derivatives conjugated to triplex-forming oligonucleotides

21 January 2018

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Sequence-specific targeting of IGF-I and IGF-IR genes by camptothecins

21 January 2018

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Targeting MDR1 gene: synthesis and cellular study of modified daunomycin-triplex-forming oligonucleotide conjugates able to inhibit gene expression in resistant cell lines.

21 January 2018

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Epigenetic reactivation of tumor suppressor genes by a novel small-molecule inhibitor of human DNA methyltransferases.

21 January 2018

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Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines.

21 January 2018

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Design, synthesis, inhibitory activity, and binding mode study of novel DNA methyltransferase 1 inhibitors

21 January 2018

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Synthesis and in vitro evaluation of biotinylated RG108: a high affinity compound for studying binding interactions with human DNA methyltransferases

21 January 2018

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Divergent modes of enzyme inhibition in a homologous structure-activity series

21 January 2018

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A detergent-based assay for the detection of promiscuous inhibitors

21 January 2018

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Effect of detergent on "promiscuous" inhibitors

21 January 2018

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Molecular modeling and molecular dynamics studies of hydralazine with human DNA methyltransferase 1.

21 January 2018

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Structure and substrate recognition of the Escherichia coli DNA adenine methyltransferase

21 January 2018

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Specificity of protein lysine methyltransferases and methods for detection of lysine methylation of non-histone proteins

21 January 2018

1 reference

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Biotin-avidin microplate assay for the quantitative analysis of enzymatic methylation of DNA by DNA methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201100522

Constrained (l-)-S-adenosyl-l-homocysteine (SAH) analogues as DNA methyltransferase inhibitors

21 January 2018

1 reference

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Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/CBIC.201100522

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11 September 2017

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