(Q39436606)

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Synthesis of cytochrome C oxidase 2: a p53-dependent metabolic regulator that promotes respiratory function and protects glioma and colon cancer cells from hypoxia-induced cell death

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Europe PubMed Central

PubMed publication ID

12 September 2017

Synthesis of cytochrome C oxidase 2: a p53-dependent metabolic regulator that promotes respiratory function and protects glioma and colon cancer cells from hypoxia-induced cell death (English)

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Europe PubMed Central

PubMed publication ID

12 September 2017

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C Wanka

1

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Europe PubMed Central

PubMed publication ID

12 September 2017

D P Brucker

2

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Europe PubMed Central

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12 September 2017

O Bähr

3

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Europe PubMed Central

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12 September 2017

M Ronellenfitsch

4

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Europe PubMed Central

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12 September 2017

M Weller

5

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Europe PubMed Central

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12 September 2017

J P Steinbach

6

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12 September 2017

J Rieger

7

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12 September 2017

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28 November 2011

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12 September 2017

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12 September 2017

31

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12 September 2017

33

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Europe PubMed Central

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12 September 2017

3764-3776

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Europe PubMed Central

PubMed publication ID

12 September 2017

https://scigraph.springernature.com/pub.10.1038/onc.2011.530

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Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment.

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TIGAR, a p53-inducible regulator of glycolysis and apoptosis

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

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Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth

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Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethality

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The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

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A noncommercial dual luciferase enzyme assay system for reporter gene analysis

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p53: guardian of the genome and policeman of the oncogenes.

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Why do cancers have high aerobic glycolysis?

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Cancer: The fat and the furious

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PI3K/PTEN signaling in tumorigenesis and angiogenesis

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AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

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Wild-type p53 in cancer cells: when a guardian turns into a blackguard

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Human SCO1 and SCO2 have independent, cooperative functions in copper delivery to cytochrome c oxidase

1 reference

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Human SCO2 is required for the synthesis of CO II and as a thiol-disulphide oxidoreductase for SCO1.

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Hypoxia induces p53-dependent transactivation and Fas/CD95-dependent apoptosis

1 reference

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A pivotal role for p53: balancing aerobic respiration and glycolysis

1 reference

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p53 regulates mitochondrial respiration

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Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II.

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Energy metabolism in tumor cells

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Dexamethasone-mediated protection from drug cytotoxicity: association with p21WAF1/CIP1 protein accumulation?

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Genetic pathways to primary and secondary glioblastoma

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Antiangiogenesis -- therapeutic strategies and clinical implications for brain tumors

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Bevacizumab-induced diffusion-restricted lesions in malignant glioma patients.

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Cell cycle analysis of p53-induced cell death in murine erythroleukemia cells

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Hypoxia-induced cell death in human malignant glioma cells: energy deprivation promotes decoupling of mitochondrial cytochrome c release from caspase processing and necrotic cell death

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Lentivirus-delivered stable gene silencing by RNAi in primary cells

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Mitochondrial respiration protects against oxygen-associated DNA damage

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Necrogenesis and Fas/APO-1 (CD95) expression in primary (de novo) and secondary glioblastomas

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Surfing the p53 network

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On the Origin of Cancer Cells

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Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas.

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p53 and its family members -- reporter genes may not see the difference

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CP-31398, a novel p53-stabilizing agent, induces p53-dependent and p53-independent glioma cell death

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PKR, a p53 target gene, plays a crucial role in the tumor-suppressor function of p53

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Cellular adaptation to hypoxia and p53 transcription regulation

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Equivalent effect of DNA damage-induced apoptotic cell death or long-term cell cycle arrest on colon carcinoma cell proliferation and tumour growth

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The regulation of energy generating metabolic pathways by p53

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The role of the Crabtree effect and an endogenous fuel in the energy metabolism of resting and proliferating thymocytes

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Current perspectives on antiangiogenesis strategies in the treatment of malignant gliomas

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Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

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10.1038/ONC.2011.530

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

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https://api.fatcat.wiki/v0/release/dm5bvxxubrc7hophrupn36bxyi

24 November 2022

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12 September 2017

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