Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q39440871)
Watch
English
TORC1 signaling inhibition by rapamycin and caffeine affect lifespan, global gene expression, and cell proliferation of fission yeast.
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
3798131
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23551936%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 February 2020
title
TORC1 signaling inhibition by rapamycin and caffeine affect lifespan, global gene expression, and cell proliferation of fission yeast
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3798131
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23551936%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 February 2020
main subject
sirolimus
1 reference
based on heuristic
inferred from title
lifetime
1 reference
based on heuristic
inferred from title
author
Charalampos Rallis
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3798131
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23551936%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 February 2020
Jurg Bahler
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3798131
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23551936%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 February 2020
author name string
Sandra Codlin
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3798131
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23551936%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 February 2020
publication date
2 May 2013
1 reference
stated in
Europe PubMed Central
PMC publication ID
3798131
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23551936%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 February 2020
published in
Aging Cell
1 reference
stated in
Europe PubMed Central
PMC publication ID
3798131
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23551936%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 February 2020
volume
12
1 reference
stated in
Europe PubMed Central
PMC publication ID
3798131
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23551936%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 February 2020
issue
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3798131
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23551936%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 February 2020
page(s)
563-573
1 reference
stated in
Europe PubMed Central
PMC publication ID
3798131
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23551936%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 February 2020
describes a project that uses
ImageJ
1 reference
stated in
Europe PubMed Central
retrieved
11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3798131/fullTextXML
based on heuristic
inferred from PubMed Central ID database lookup
cites work
Cell size control in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
mTOR signaling in growth control and disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
FDA-approved drugs that protect mammalian neurons from glucose toxicity slow aging dependent on cbp and protect against proteotoxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Composition and acidification of the culture medium influences chronological aging similarly in vineyard and laboratory yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Extending healthy life span--from yeast to humans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Lessons on longevity from budding yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Fission yeast TORC1 regulates phosphorylation of ribosomal S6 proteins in response to nutrients and its activity is inhibited by rapamycin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Cellular quiescence: are controlling genes conserved?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Genome-wide screen of genes required for caffeine tolerance in fission yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Pro-aging effects of glucose signaling through a G protein-coupled glucose receptor in fission yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Caffeine: neuroprotective functions in cognition and Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Tuning gene expression to changing environments: from rapid responses to evolutionary adaptation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
The TSC1-TSC2 complex: a molecular switchboard controlling cell growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Sch9 is a major target of TORC1 in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
A network of multiple regulatory layers shapes gene expression in fission yeast.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Loss of the TOR kinase Tor2 mimics nitrogen starvation and activates the sexual development pathway in fission yeast.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Global roles of Ste11p, cell type, and pheromone in the control of gene expression during early sexual differentiation in fission yeast.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
TOR signaling in growth and metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Extension of chronological life span in yeast by decreased TOR pathway signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Selective inhibition of the DNA-dependent protein kinase (DNA-PK) by the radiosensitizing agent caffeine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Whole-genome microarrays of fission yeast: characteristics, accuracy, reproducibility, and processing of array data
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Caffeine can override the S-M checkpoint in fission yeast.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Rapamycin sensitivity in Saccharomyces cerevisiae is mediated by a peptidyl-prolyl cis-trans isomerase related to human FK506-binding protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
12 September 2017
Lifespan extension by calorie restriction relies on the Sty1 MAP kinase stress pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
14 September 2017
Global transcriptional responses of fission yeast to environmental stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
14 September 2017
Caffeine extends yeast lifespan by targeting TORC1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
14 September 2017
The reverse, but coordinated, roles of Tor2 (TORC1) and Tor1 (TORC2) kinases for growth, cell cycle and separase-mediated mitosis in Schizosaccharomyces pombe
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
15 June 2018
Fission yeast TOR complex 2 activates the AGC-family Gad8 kinase essential for stress resistance and cell cycle control.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
15 June 2018
Fission yeast Tor2 promotes cell growth and represses cell differentiation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
15 June 2018
Fission yeast Tor1 functions as part of TORC1 to control mitotic entry through the stress MAPK pathway following nutrient stress.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
21 August 2018
Caffeine prevents age-associated recognition memory decline and changes brain-derived neurotrophic factor and tirosine kinase receptor (TrkB) content in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
21 August 2018
TOR signalling regulates mitotic commitment through the stress MAP kinase pathway and the Polo and Cdc2 kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
21 August 2018
Fission yeast Tor2 links nitrogen signals to cell proliferation and acts downstream of the Rheb GTPase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
21 August 2018
The transcriptional program of meiosis and sporulation in fission yeast.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
21 August 2018
Rapamycin blocks sexual development in fission yeast through inhibition of the cellular function of an FKBP12 homolog
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
21 August 2018
Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798131
retrieved
21 August 2018
TORC1 of fission yeast is rapamycin-sensitive
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23551936
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1111/ACEL.12080
1 reference
stated in
Europe PubMed Central
PMC publication ID
3798131
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23551936%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 February 2020
PMC publication ID
3798131
1 reference
stated in
Europe PubMed Central
PMC publication ID
3798131
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23551936%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 February 2020
PubMed publication ID
23551936
1 reference
stated in
Europe PubMed Central
PMC publication ID
3798131
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23551936%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 February 2020
ResearchGate publication ID
236102971
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit