(Q39443547)

12 September 2017

title

EGFR signaling upregulates expression of microsomal prostaglandin E synthase-1 in cancer cells leading to enhanced tumorigenicity (English)

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12 September 2017

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S Donnini

1

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12 September 2017

F Finetti

2

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12 September 2017

E Terzuoli

3

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12 September 2017

A Giachetti

4

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12 September 2017

M A Iñiguez

5

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12 September 2017

H Hanaka

6

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12 September 2017

M Fresno

7

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12 September 2017

O Rådmark

8

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12 September 2017

M Ziche

9

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12 September 2017

language of work or name

English

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publication date

14 November 2011

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12 September 2017

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12 September 2017

volume

31

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12 September 2017

issue

29

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12 September 2017

page(s)

3457-3466

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https://scigraph.springernature.com/pub.10.1038/onc.2011.503

12 September 2017

exact match

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cites work

Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Activation of peroxisome proliferator-activated receptor gamma inhibits interleukin-1beta-induced membrane-associated prostaglandin E2 synthase-1 expression in human synovial fibroblasts by interfering with Egr-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Interaction between epidermal growth factor receptor- and cyclooxygenase 2-mediated pathways and its implications for the chemoprevention of head and neck cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

EGFR antagonists in cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

The early response gene NGFI-C encodes a zinc finger transcriptional activator and is a member of the GCGGGGGCG (GSG) element-binding protein family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

New strategies in colorectal cancer: biomarkers of response to epidermal growth factor receptor monoclonal antibodies and potential therapeutic targets in phosphoinositide 3-kinase and mitogen-activated protein kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Dimethylcelecoxib inhibits mPGES-1 promoter activity by influencing EGR1 and NF-κB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Coordinated up-regulation of cyclooxygenase-2 and microsomal prostaglandin E synthase 1 transcription by nuclear factor kappa B and early growth response-1 in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

EP2 prostanoid receptor promotes squamous cell carcinoma growth through epidermal growth factor receptor transactivation and iNOS and ERK1/2 pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Prostaglandin E(2) primes the angiogenic switch via a synergic interaction with the fibroblast growth factor-2 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Cyclooxygenase-2 and microsomal prostaglandin E synthase-1 are overexpressed in squamous cell carcinoma of the penis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Microsomal prostaglandin E synthase 1 determines tumor growth in vivo of prostate and lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Novel monoclonal antibody specific for the de2-7 epidermal growth factor receptor (EGFR) that also recognizes the EGFR expressed in cells containing amplification of the EGFR gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Potential role of microsomal prostaglandin E synthase-1 in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

PGE2 inhibits apoptosis in human adenocarcinoma Caco-2 cell line through Ras-PI3K association and cAMP-dependent kinase A activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

A cytokine-mediated link between innate immunity, inflammation, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Microsomal prostaglandin E synthase-1 promotes hepatocarcinogenesis through activation of a novel EGR1/β-catenin signaling axis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Repression of prostaglandin dehydrogenase by epidermal growth factor and snail increases prostaglandin E2 and promotes cancer progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Cyclooxygenase-2 and cancer treatment: understanding the risk should be worth the reward

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Epidermal growth factor increases prostaglandin E2 production via ERK1/2 MAPK and NF-kappaB pathway in fibroblast like synoviocytes from patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Genetic deletion of mPGES-1 suppresses intestinal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Transcriptional regulation of the membrane-associated prostaglandin E2 synthase gene. Essential role of the transcription factor Egr-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Involvement of the NGFI-A gene in the differentiation of neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Colon carcinoma cell growth is associated with prostaglandin E2/EP4 receptor-evoked ERK activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Membrane prostaglandin E synthase-1: a novel therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Microsomal prostaglandin E synthase-1 is overexpressed in inflammatory bowel disease. Evidence for involvement of the transcription factor Egr-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Epithelial-mesenchymal transitions in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

21 January 2018

Eicosanoids and cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Prostaglandin E2 reduces radiation-induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

Testing for colon neoplasia susceptibility variants at the human COX2 locus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.503

31 March 2020

Identifiers

DOI

10.1038/ONC.2011.503

1 reference

12 September 2017

1 reference