(Q39455159)

12 September 2017

title

Centrosomal targeting of tyrosine kinase activity does not enhance oncogenicity in chronic myeloproliferative disorders (English)

1 reference

12 September 2017

U Klingmüller

5

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author name string

T Bochtler

1

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12 September 2017

M Kirsch

2

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12 September 2017

B Maier

3

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12 September 2017

J Bachmann

4

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12 September 2017

S Anderhub

6

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12 September 2017

A D Ho

7

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12 September 2017

A Krämer

8

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12 September 2017

publication date

21 October 2011

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12 September 2017

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12 September 2017

volume

26

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12 September 2017

issue

4

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12 September 2017

page(s)

728-735

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Oncogenic mechanisms in myeloproliferative disorders

12 September 2017

cites work

1 reference

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Oncogenes in myeloproliferative disorders

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Distinct stem cell myeloproliferative/T lymphoma syndromes induced by ZNF198-FGFR1 and BCR-FGFR1 fusion genes from 8p11 translocations

21 January 2018

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8p12 stem cell myeloproliferative disorder: the FOP-fibroblast growth factor receptor 1 fusion protein of the t(6;8) translocation induces cell survival mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt/mTOR pathways

21 January 2018

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The t(8;17)(p11;q23) in the 8p11 myeloproliferative syndrome fuses MYO18A to FGFR1.

21 January 2018

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The t(8;9)(p22;p24) is a recurrent abnormality in chronic and acute leukemia that fuses PCM1 to JAK2

21 January 2018

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PCM1-JAK2 fusion in myeloproliferative disorders and acute erythroid leukemia with t(8;9) translocation

21 January 2018

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The t(8;9)(p22;p24) translocation in atypical chronic myeloid leukaemia yields a new PCM1-JAK2 fusion gene

21 January 2018

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Transient response to imatinib in a chronic eosinophilic leukemia associated with ins(9;4)(q33;q12q25) and a CDK5RAP2-PDGFRA fusion gene.

21 January 2018

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Cloning of the t(1;5)(q23;q33) in a myeloproliferative disorder associated with eosinophilia: involvement of PDGFRB and response to imatinib

21 January 2018

1 reference

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NIN, a gene encoding a CEP110-like centrosomal protein, is fused to PDGFRB in a patient with a t(5;14)(q33;q24) and an imatinib-responsive myeloproliferative disorder

21 January 2018

1 reference

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p53-Binding protein 1 is fused to the platelet-derived growth factor receptor beta in a patient with a t(5;15)(q33;q22) and an imatinib-responsive eosinophilic myeloproliferative disorder

21 January 2018

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Microtubule-organizing centres: a re-evaluation.

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Centrosome control of the cell cycle

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Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase

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Centrosome aberrations: cause or consequence of cancer progression?

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Centrosome aberrations in chronic myeloid leukemia correlate with stage of disease and chromosomal instability

21 January 2018

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Myeloproliferative disorders: the centrosome connection

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Oncogenic tyrosine kinase of malignant hemopathy targets the centrosome.

21 January 2018

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Myeloproliferative disorder FOP-FGFR1 fusion kinase recruits phosphoinositide-3 kinase and phospholipase Cgamma at the centrosome

21 January 2018

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Structure of the N-terminal domain of the FOP (FGFR1OP) protein and implications for its dimerization and centrosomal localization

21 January 2018

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The PACT domain, a conserved centrosomal targeting motif in the coiled-coil proteins AKAP450 and pericentrin.

21 January 2018

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Cep164, a novel centriole appendage protein required for primary cilium formation

21 January 2018

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Microtubule nucleation and anchoring at the centrosome are independent processes linked by ninein function

21 January 2018

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H4(D10S170), a gene frequently rearranged in papillary thyroid carcinoma, is fused to the platelet-derived growth factor receptor beta gene in atypical chronic myeloid leukemia with t(5;10)(q33;q22).

21 January 2018

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Co-regulation of two gene activities by tetracycline via a bidirectional promoter.

21 January 2018

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Model-based extension of high-throughput to high-content data

21 January 2018

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Molecular characterization of human ninein protein: two distinct subdomains required for centrosomal targeting and regulating signals in cell cycle

21 January 2018

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A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size

21 January 2018

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CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the gamma-tubulin ring complex

21 January 2018

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Activation of FIP1L1-PDGFRalpha requires disruption of the juxtamembrane domain of PDGFRalpha and is FIP1L1-independent

21 January 2018

1 reference

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The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways

21 January 2018

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Expression of the p210BCR-ABL oncoprotein drives centrosomal hypertrophy and clonal evolution in human U937 cells

21 January 2018

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Centrosome aberrations and G1 phase arrest after in vitro and in vivo treatment with the SRC/ABL inhibitor dasatinib

21 January 2018

1 reference

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The coiled-coil domain and Tyr177 of bcr are required to induce a murine chronic myelogenous leukemia-like disease by bcr/abl.

21 January 2018

1 reference

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Role of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.283

8p11 myeloproliferative syndrome: a review.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.283

Phosphorylation of the SSBP2 and ABL proteins by the ZNF198-FGFR1 fusion kinase seen in atypical myeloproliferative disorders as revealed by phosphopeptide-specific MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.283

Centrosome aberrations after nilotinib and imatinib treatment in vitro are associated with mitotic spindle defects and genetic instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.283

A new NDE1/PDGFRB fusion transcript underlying chronic myelomonocytic leukaemia in Noonan Syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.283

inferred from DOI database lookup

7 January 2021

based on heuristic

Centrosome aberrations in acute myeloid leukemia are correlated with cytogenetic risk profile

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.283

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/LEU.2011.283

1 reference

Dimensions Publication ID

12 September 2017

1007818422

0 references

1 reference