(Q39469395)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21941364%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Impaired bortezomib binding to mutant β5 subunit of the proteasome is the underlying basis for bortezomib resistance in leukemia cells (English)

1 reference

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13 February 2020

1 reference

10

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13 February 2020

Aaron Schimmer

11

1 reference

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13 February 2020

7

S Zweegman

1 reference

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13 February 2020

author name string

N E Franke

1

1 reference

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13 February 2020

D Niewerth

2

1 reference

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13 February 2020

Y G Assaraf

3

1 reference

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13 February 2020

J van Meerloo

4

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13 February 2020

K Vojtekova

5

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13 February 2020

C H van Zantwijk

6

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13 February 2020

E T Chan

8

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13 February 2020

C J Kirk

9

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13 February 2020

G J L Kaspers

12

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13 February 2020

G Jansen

13

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13 February 2020

J Cloos

14

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13 February 2020

publication date

23 September 2011

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13 February 2020

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13 February 2020

volume

26

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13 February 2020

issue

4

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13 February 2020

page(s)

757-768

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https://scigraph.springernature.com/pub.10.1038/leu.2011.256

13 February 2020

exact match

0 references

cites work

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Comparative selectivity and specificity of the proteasome inhibitors BzLLLCOCHO, PS-341, and MG-132.

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The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications

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Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341.

21 January 2018

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Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells

21 January 2018

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Molecular sequelae of proteasome inhibition in human multiple myeloma cells

21 January 2018

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Proteasome inhibition as novel treatment strategy in leukaemia

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Activity patterns of proteasome subunits reflect bortezomib sensitivity of hematologic malignancies and are variable in primary human leukemia cells

21 January 2018

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Characterization of the ubiquitin-proteasome system in bortezomib-adapted cells

21 January 2018

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Point mutation of the proteasome beta5 subunit gene is an important mechanism of bortezomib resistance in bortezomib-selected variants of Jurkat T cell lymphoblastic lymphoma/leukemia line

21 January 2018

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Molecular basis of bortezomib resistance: proteasome subunit beta5 (PSMB5) gene mutation and overexpression of PSMB5 protein

21 January 2018

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Bortezomib-resistant myeloma cell lines: a role for mutated PSMB5 in preventing the accumulation of unfolded proteins and fatal ER stress

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21 January 2018

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21 January 2018

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A novel orally active proteasome inhibitor ONX 0912 triggers in vitro and in vivo cytotoxicity in multiple myeloma

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Cells adapted to the proteasome inhibitor 4-hydroxy- 5-iodo-3-nitrophenylacetyl-Leu-Leu-leucinal-vinyl sulfone require enzymatically active proteasomes for continued survival

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Pharmacogenomics of bortezomib test-dosing identifies hyperexpression of proteasome genes, especially PSMD4, as novel high-risk feature in myeloma treated with Total Therapy 3

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.256

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/LEU.2011.256

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21941364%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference