(Q39473750)

English

Elevated Mirc1/Mir17-92 cluster expression negatively regulates autophagy and CFTR (cystic fibrosis transmembrane conductance regulator) function in CF macrophages.

scientific article published on 19 August 2016

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scholarly article

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21 March 2020

Elevated Mirc1/Mir17-92 cluster expression negatively regulates autophagy and CFTR (cystic fibrosis transmembrane conductance regulator) function in CF macrophages (English)

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21 March 2020

cystic fibrosis

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transmembrane protein

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1 reference

based on heuristic

inferred from title

Duaa Dakhlallah

2

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21 March 2020

6

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21 March 2020

author name string

Mia F Tazi

1

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21 March 2020

Kyle Caution

3

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21 March 2020

Madelyn M Gerber

4

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21 March 2020

Sheng-Wei Chang

5

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21 March 2020

Benjamin T Kopp

7

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21 March 2020

Amr E Ahmed

8

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21 March 2020

Kathrin Krause

9

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21 March 2020

Ian Davis

10

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21 March 2020

Clay Marsh

11

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21 March 2020

Amy E Lovett-Racke

12

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21 March 2020

Larry S Schlesinger

13

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21 March 2020

Estelle Cormet-Boyaka

14

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21 March 2020

Amal O Amer

15

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21 March 2020

publication date

1 November 2016

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21 March 2020

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21 March 2020

12

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21 March 2020

11

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21 March 2020

2026-2037

1 reference

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21 March 2020

describes a project that uses

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11 June 2022

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based on heuristic

inferred from PubMed Central ID database lookup

Innate and Adaptive Immunity in Cystic Fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Lumacaftor and ivacaftor in the management of patients with cystic fibrosis: current evidence and future prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

The cooperation between the autophagy machinery and the inflammasome to implement an appropriate innate immune response: do they regulate each other?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Potentiators (specific therapies for class III and IV mutations) for cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

IFN-γ stimulates autophagy-mediated clearance of Burkholderia cenocepacia in human cystic fibrosis macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Inhibition of miR-25 improves cardiac contractility in the failing heart.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

The emerging potential of autophagy-based therapies in the treatment of cystic fibrosis lung infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Cystic fibrosis transmembrane conductance regulator recruitment to phagosomes in neutrophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Regulation of cystic fibrosis transmembrane conductance regulator by microRNA-145, -223, and -494 is altered in ΔF508 cystic fibrosis airway epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Rescue of dysfunctional autophagy attenuates hyperinflammatory responses from cystic fibrosis cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Depletion of the ubiquitin-binding adaptor molecule SQSTM1/p62 from macrophages harboring cftr ΔF508 mutation improves the delivery of Burkholderia cenocepacia to the autophagic machinery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Innate immunity in cystic fibrosis lung disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ΔF508 cystic fibrosis transmembrane conductance regulator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

A microRNA network regulates expression and biosynthesis of wild-type and DeltaF508 mutant cystic fibrosis transmembrane conductance regulator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Exaggerated inflammatory responses mediated by Burkholderia cenocepacia in human macrophages derived from Cystic fibrosis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Pri-miR-17-92a transcript folds into a tertiary structure and autoregulates its processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Autophagy stimulation by rapamycin suppresses lung inflammation and infection by Burkholderia cenocepacia in a model of cystic fibrosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

microRNA-101 is a potent inhibitor of autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

MicroRNA regulation of expression of the cystic fibrosis transmembrane conductance regulator gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Eaten alive: a history of macroautophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Lung microRNA: from development to disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

miR-17-92 cluster: ups and downs in cancer and aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

mir-17-92, a cluster of miRNAs in the midst of the cancer network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Cystic fibrosis and innate immunity: how chloride channel mutations provoke lung disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

MicroRNA regulation of a cancer network: consequences of the feedback loops involving miR-17-92, E2F, and Myc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

miRiad roles for the miR-17-92 cluster in development and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Cystic fibrosis mouse models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Silencing of microRNAs in vivo with 'antagomirs'

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Autophagy is an immediate macrophage response to Legionella pneumophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Silencing T-bet defines a critical role in the differentiation of autoreactive T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

The "Goldilocks effect" in cystic fibrosis: identification of a lung phenotype in the cftr knockout and heterozygous mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Rescuing cystic fibrosis transmembrane conductance regulator (CFTR)-processing mutants by transcomplementation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Abnormal surface liquid pH regulation by cultured cystic fibrosis bronchial epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

The molecular mechanism of autophagy

1 reference

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12 September 2017

Inhibitors of mammalian target of rapamycin as novel antitumor agents: from bench to clinic.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Autophagy as a regulated pathway of cellular degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Active intestinal chloride secretion in human carriers of cystic fibrosis mutations: an evaluation of the hypothesis that heterozygotes have subnormal active intestinal chloride secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Role of the cystic fibrosis transmembrane conductance regulator in innate immunity to Pseudomonas aeruginosa infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Inflammation and CFTR: might neutrophils be the key in cystic fibrosis?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

A protein conjugation system essential for autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

A delta F508 mutation in mouse cystic fibrosis transmembrane conductance regulator results in a temperature-sensitive processing defect in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Cystic Fibrosis Heterozygote Resistance to Cholera Toxin in the Cystic Fibrosis Mouse Model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

miR-17-92 cluster microRNAs confers tumorigenicity in multiple myeloma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

12 September 2017

Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

14 September 2017

Low temperature restoring effect on F508del-CFTR misprocessing: A proteomic approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

14 September 2017

Dysfunction of CFTR bearing the delta F508 mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

14 September 2017

Aging is associated with hypermethylation of autophagy genes in macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

25 September 2017

Cellular localisation of the most common mutant form of the CF gene protein, delta F508-CFTR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

25 September 2017

Intracellular loop between transmembrane segments IV and V of cystic fibrosis transmembrane conductance regulator is involved in regulation of chloride channel conductance state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

25 September 2017

Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

17 June 2018

Towards a rational combination therapy of cystic fibrosis: How cystamine restores the stability of mutant CFTR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

21 August 2018

Epigenetic regulation of miR-17~92 contributes to the pathogenesis of pulmonary fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

21 August 2018

Cancer risk in cystic fibrosis: a 20-year nationwide study from the United States

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

21 August 2018

Regulation of microRNA biogenesis and function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

21 August 2018

MicroRNA profiling of cystic fibrosis intestinal disease in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

21 August 2018

Risk of pancreatic cancer in patients with cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

21 August 2018

Normal function of the cystic fibrosis conductance regulator protein can be associated with homozygous (Delta)F508 mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103351

21 August 2018

Cellular heterogeneity of CFTR expression and function in the lung: implications for gene therapy of cystic fibrosis.

1 reference

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21 August 2018

The Risk of Cancer among Patients with Cystic Fibrosis

1 reference

https://api.crossref.org/works/10.1080%2F15548627.2016.1217370

21 January 2018

Cystic fibrosis: A disorder with defective autophagy

1 reference

https://api.crossref.org/works/10.1080%2F15548627.2016.1217370

21 January 2018

p62/SQSTM1: a missing link between protein aggregates and the autophagy machinery

1 reference

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4 November 2018

The microRNA-17~92 cluster: Still a miRacle?

1 reference

https://api.crossref.org/works/10.1080%2F15548627.2016.1217370

21 January 2018

The molecular machinery of autophagy and its role in physiology and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/27541364

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ion and fluid transport properties of small airways in cystic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/27541364

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Screening for cystic fibrosis: use of delta F508 mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/27541364

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cystic fibrosis delta F508 gene mutation and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/27541364

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1080/15548627.2016.1217370

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27541364%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27541364%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27541364%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

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