(Q39475539)

12 September 2017

Synthesis and evaluation of 7-substituted 4-aminoquinoline analogues for antimalarial activity (English)

1 reference

12 September 2017

0 references

7

W Armand Guiguemde

1 reference

12 September 2017

11

R Kiplin Guy

1 reference

12 September 2017

5

Michele C Connelly

1 reference

12 September 2017

6

Fangyi Zhu

1 reference

12 September 2017

10

Joseph L Derisi

1 reference

12 September 2017

8

Martina S Sigal

1 reference

12 September 2017

Jong Yeon Hwang

1

1 reference

12 September 2017

Takashi Kawasuji

2

1 reference

12 September 2017

David J Lowes

3

1 reference

12 September 2017

Julie A Clark

4

1 reference

12 September 2017

Emily B Wilson

9

1 reference

12 September 2017

language of work or name

English

0 references

publication date

26 September 2011

1 reference

Journal of Medicinal Chemistry

12 September 2017

1 reference

12 September 2017

54

1 reference

12 September 2017

20

1 reference

12 September 2017

7084-7093

1 reference

Chemical genetics of Plasmodium falciparum

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

That Was Then But This Is Now: Malaria Research in the Time of an Eradication Agenda

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

Quinolines and structurally related heterocycles as antimalarials

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

Development of a new generation of 4-aminoquinoline antimalarial compounds using predictive pharmacokinetic and toxicology models.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

Structure-activity relationship study of 9-aminoacridine compounds in scrapie-infected neuroblastoma cells

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

Effectiveness of antimalarial drugs

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

Catalysts for Suzuki-Miyaura coupling processes: scope and studies of the effect of ligand structure

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

Parallel synthesis and antimalarial screening of a 4-aminoquinoline library

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

12 September 2017

New Antimalarial Drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

Aryl-aryl bond formation one century after the discovery of the Ullmann reaction

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

Human malaria parasites in continuous culture

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

Simple and inexpensive fluorescence-based technique for high-throughput antimalarial drug screening.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

Trioxaferroquines as new hybrid antimalarial drugs.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

Synthesis and biological evaluation of the first pentafluorosulfanyl analogs of mefloquine

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

Overcoming drug resistance to heme-targeted antimalarials by systematic side chain variation of 7-chloro-4-aminoquinolines

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

Incorporation of an intramolecular hydrogen-bonding motif in the side chain of 4-aminoquinolines enhances activity against drug-resistant P. falciparum.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

Synthesis of ring-substituted 4-aminoquinolines and evaluation of their antimalarial activities.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

Carbon isosteres of the 4-aminopyridine substructure of chloroquine: effects on pK(a), hematin binding, inhibition of hemozoin formation, and parasite growth

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

Structure-activity relationships in 4-aminoquinoline antiplasmodials. The role of the group at the 7-position

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

Prophylactic activity of mefloquine hydrochloride (WR 142490) in drug-resistant malaria

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

4-N-, 4-S-, and 4-O-chloroquine analogues: influence of side chain length and quinolyl nitrogen pKa on activity vs chloroquine resistant malaria

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

Absorption-excipient-pH classification gradient maps: sparingly soluble drugs and the pH partition hypothesis

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

Solubility-excipient classification gradient maps.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697074

PAMPA--critical factors for better predictions of absorption

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21910466

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A general and mild Ullmann-type synthesis of diaryl ethers

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21910466

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JM200636Z

1 reference

12 September 2017

1 reference

12 September 2017

PubMed publication ID

21910466

1 reference