(Q39478013)

English

Phosphatidylinositol-3-kinase (PI3K) is activated by influenza virus vRNA via the pathogen pattern receptor Rig-I to promote efficient type I interferon production

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scholarly article

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Europe PubMed Central

PubMed publication ID

12 September 2017

Phosphatidylinositol-3-kinase (PI3K) is activated by influenza virus vRNA via the pathogen pattern receptor Rig-I to promote efficient type I interferon production (English)

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

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Stephan Ludwig

5

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author name string

Eike R Hrincius

1

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Rüdiger Dierkes

2

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Darisuren Anhlan

3

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Viktor Wixler

4

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Christina Ehrhardt

6

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Europe PubMed Central

PubMed publication ID

12 September 2017

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11 October 2011

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Europe PubMed Central

PubMed publication ID

12 September 2017

Cellular Microbiology

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Europe PubMed Central

PubMed publication ID

12 September 2017

13

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Europe PubMed Central

PubMed publication ID

12 September 2017

12

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

1907-1919

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

The Ebola virus VP35 protein functions as a type I IFN antagonist.

1 reference

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21 January 2018

Signal regulatory protein alpha negatively regulates both TLR3 and cytoplasmic pathways in type I interferon induction

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

A new player in a deadly game: influenza viruses and the PI3K/Akt signalling pathway

1 reference

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21 January 2018

Rac1 and PAK1 are upstream of IKK-epsilon and TBK-1 in the viral activation of interferon regulatory factor-3.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Bivalent role of the phosphatidylinositol-3-kinase (PI3K) during influenza virus infection and host cell defence

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Activation of phosphatidylinositol 3-kinase signaling by the nonstructural NS1 protein is not conserved among type A and B influenza viruses

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

The epidermal growth factor receptor (EGFR) promotes uptake of influenza A viruses (IAV) into host cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Triggering the interferon response: the role of IRF-3 transcription factor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Loss of function of the influenza A virus NS1 protein promotes apoptosis but this is not due to a failure to activate phosphatidylinositol 3-kinase (PI3K).

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

When two strands are better than one: the mediators and modulators of the cellular responses to double-stranded RNA.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Strand-specific real-time RT-PCR for distinguishing influenza vRNA, cRNA, and mRNA

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Innate immune response to viral infection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Avian influenza virus A/HK/483/97(H5N1) NS1 protein induces apoptosis in human airway epithelial cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate Immunity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Viral double-stranded RNA, cytokines, and the flu.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Activation of innate defense against a paramyxovirus is mediated by RIG-I and TLR7 and TLR8 in a cell-type-specific manner

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

The nuclear phosphoinositide 3-kinase/AKT pathway: a new second messenger system.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

IFNbeta induction by influenza A virus is mediated by RIG-I which is regulated by the viral NS1 protein

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Human neuronal cells possess functional cytoplasmic and TLR-mediated innate immune pathways influenced by phosphatidylinositol-3 kinase signaling.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Influenza virus ns1 protein induces apoptosis in cultured cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Triggering the interferon antiviral response through an IKK-related pathway

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Influenza A virus NS1 protein activates the phosphatidylinositol 3-kinase (PI3K)/Akt pathway by direct interaction with the p85 subunit of PI3K.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

SH3 binding motif 1 in influenza A virus NS1 protein is essential for PI3K/Akt signaling pathway activation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Interferon-induced human protein with homology to protein Mx of influenza virus-resistant mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Innate immunity to virus infection.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

The PI3K-PDK1 connection: more than just a road to PKB

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Signaling by distinct classes of phosphoinositide 3-kinases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Signalling by PI3K isoforms: insights from gene-targeted mice.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Function of RIG-I-like receptors in antiviral innate immunity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Cytokine-independent upregulation of MDA5 in viral infection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

MDA5 participates in the detection of paramyxovirus infection and is essential for the early activation of dendritic cells in response to Sendai Virus defective interfering particles

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Control of apoptosis in influenza virus-infected cells by up-regulation of Akt and p53 signaling

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01680.X

21 January 2018

Identifiers

10.1111/J.1462-5822.2011.01680.X

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

ResearchGate publication ID

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