(Q39491265)

English

Novel C-terminal Hsp90 inhibitor for head and neck squamous cell cancer (HNSCC) with in vivo efficacy and improved toxicity profiles compared with standard agents

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

2 March 2018

http://europepmc.org/abstract/PMC/5828498

Novel C-terminal Hsp90 inhibitor for head and neck squamous cell cancer (HNSCC) with in vivo efficacy and improved toxicity profiles compared with standard agents (English)

1 reference

Europe PubMed Central

PMC publication ID

2 March 2018

http://europepmc.org/abstract/PMC/5828498

6

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Brian S J Blagg

1 reference

Europe PubMed Central

PMC publication ID

2 March 2018

http://europepmc.org/abstract/PMC/5828498

author name string

Stephanie M Cohen

1

1 reference

Europe PubMed Central

PMC publication ID

2 March 2018

http://europepmc.org/abstract/PMC/5828498

Ridhwi Mukerji

2

1 reference

Europe PubMed Central

PMC publication ID

2 March 2018

http://europepmc.org/abstract/PMC/5828498

Abbas K Samadi

3

1 reference

Europe PubMed Central

PMC publication ID

2 March 2018

http://europepmc.org/abstract/PMC/5828498

Xuan Zhang

4

1 reference

Europe PubMed Central

PMC publication ID

2 March 2018

http://europepmc.org/abstract/PMC/5828498

Huiping Zhao

5

1 reference

Europe PubMed Central

PMC publication ID

2 March 2018

http://europepmc.org/abstract/PMC/5828498

Mark S Cohen

7

1 reference

Europe PubMed Central

PMC publication ID

2 March 2018

http://europepmc.org/abstract/PMC/5828498

publication date

12 August 2011

1 reference

Europe PubMed Central

PMC publication ID

2 March 2018

http://europepmc.org/abstract/PMC/5828498

Annals of Surgical Oncology

1 reference

Europe PubMed Central

PMC publication ID

2 March 2018

http://europepmc.org/abstract/PMC/5828498

19 Suppl 3

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Europe PubMed Central

PMC publication ID

2 March 2018

http://europepmc.org/abstract/PMC/5828498

S483-90

1 reference

Europe PubMed Central

PMC publication ID

2 March 2018

http://europepmc.org/abstract/PMC/5828498

https://scigraph.springernature.com/pub.10.1245/s10434-011-1971-1

0 references

Head and neck cancer: changing epidemiology and public health implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

17 June 2018

Hsp90 (heat shock protein 90) inhibitor occupancy is a direct determinant of client protein degradation and tumor growth arrest in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

17 June 2018

Activity of anticancer agents in a three-dimensional cell culture model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

17 June 2018

Cancer statistics, 2010

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

17 June 2018

Alternate strategies of Hsp90 modulation for the treatment of cancer and other diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

17 June 2018

Characterization of celastrol to inhibit hsp90 and cdc37 interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

17 June 2018

HPV & head and neck cancer: a descriptive update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

17 June 2018

KU135, a novel novobiocin-derived C-terminal inhibitor of the 90-kDa heat shock protein, exerts potent antiproliferative effects in human leukemic cells

1 reference

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17 June 2018

BIIB021, a novel Hsp90 inhibitor, sensitizes head and neck squamous cell carcinoma to radiotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

17 June 2018

Phase II trial of 17-allylamino-17-demethoxygeldanamycin in patients with metastatic melanoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

17 June 2018

Novobiocin and additional inhibitors of the Hsp90 C-terminal nucleotide-binding pocket

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

17 June 2018

Head and neck cancer: changing epidemiology, diagnosis, and treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

17 June 2018

Hsp90: a novel target for the disruption of multiple signaling cascades

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

17 June 2018

Targeting of multiple signalling pathways by heat shock protein 90 molecular chaperone inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

17 June 2018

The epidemiology and risk factors of head and neck cancer: a focus on human papillomavirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

17 June 2018

Targeting multiple signal transduction pathways through inhibition of Hsp90.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

17 June 2018

Hsp90 isoforms: functions, expression and clinical importance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

17 June 2018

Combinatorial attack on multistep oncogenesis by inhibiting the Hsp90 molecular chaperone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

17 June 2018

Auditing the pharmacological accounts for Hsp90 molecular chaperone inhibitors: unfolding the relationship between pharmacokinetics and pharmacodynamics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

17 June 2018

HSP90 as a new therapeutic target for cancer therapy: the story unfolds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

17 June 2018

A Phase II trial of 17-allylamino, 17-demethoxygeldanamycin (17-AAG, tanespimycin) in patients with metastatic melanoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

21 August 2018

ITZ-1, a client-selective Hsp90 inhibitor, efficiently induces heat shock factor 1 activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

21 August 2018

Potent activity of a novel dimeric heat shock protein 90 inhibitor against head and neck squamous cell carcinoma in vitro and in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

21 August 2018

Comparison of 17-dimethylaminoethylamino-17-demethoxy-geldanamycin (17DMAG) and 17-allylamino-17-demethoxygeldanamycin (17AAG) in vitro: effects on Hsp90 and client proteins in melanoma models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

21 August 2018

The heat-shock response: regulation and function of heat-shock proteins and molecular chaperones.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828498

21 August 2018

Postoperative Concurrent Radiotherapy and Chemotherapy for High-Risk Squamous-Cell Carcinoma of the Head and Neck

1 reference

https://api.crossref.org/works/10.1245%2FS10434-011-1971-1

21 January 2018

Telomerase as a Target for Cancer Immunotherapy

1 reference

https://api.crossref.org/works/10.1245%2FS10434-011-1971-1

21 January 2018

Novobiocin and related coumarins and depletion of heat shock protein 90-dependent signaling proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/21837531

12 December 2020

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inferred from PubMed ID database lookup

Identifiers

10.1245/S10434-011-1971-1

1 reference

Europe PubMed Central

PMC publication ID

2 March 2018

http://europepmc.org/abstract/PMC/5828498

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

2 March 2018

http://europepmc.org/abstract/PMC/5828498

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

2 March 2018

http://europepmc.org/abstract/PMC/5828498

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