(Q39497573)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21804968%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Synthesis, structures, cellular uptake and apoptosis-inducing properties of highly cytotoxic ruthenium-Norharman complexes (English)

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9 February 2020

0 references

0 references

1 reference

1

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9 February 2020

author name string

Shouhai Wu

2

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9 February 2020

Sensen Lai

3

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9 February 2020

Minxu Wang

4

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9 February 2020

Yu Chen

5

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9 February 2020

Lingjun Zhou

6

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9 February 2020

Yiping Zhu

7

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9 February 2020

Wu Lian

8

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9 February 2020

Wenlie Peng

9

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9 February 2020

Liangnian Ji

10

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9 February 2020

Anlong Xu

11

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9 February 2020

language of work or name

English

0 references

publication date

29 July 2011

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9 February 2020

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9 February 2020

volume

40

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9 February 2020

issue

34

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9 February 2020

page(s)

8611-8621

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Ruthenium complexes as anticancer agents

9 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Ruthenium-based chemotherapeutics: are they ready for prime time?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

A Phase I and pharmacological study with imidazolium-trans-DMSO-imidazole-tetrachlororuthenate, a novel ruthenium anticancer agent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

KP1019, a new redox-active anticancer agent--preclinical development and results of a clinical phase I study in tumor patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Recent developments in ruthenium anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Medicinal organometallic chemistry: designing metal arene complexes as anticancer agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Synthesis, X-ray diffraction structure, spectroscopic properties and antiproliferative activity of a novel ruthenium complex with constitutional similarity to cisplatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

The ruthenium(II)-arene compound RAPTA-C induces apoptosis in EAC cells through mitochondrial and p53-JNK pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Arene ruthenium complexes as anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Recognition and reaction of metallointercalators with DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Kinetically inert transition metal complexes that reversibly bind to DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Metallo-intercalators and metallo-insertors

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

The Brønsted acid-catalyzed direct aza-Darzens synthesis of N-alkyl cis-aziridines

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

DNA binding, photocleavage, and topoisomerase inhibition of functionalized ruthenium(II)-polypyridine complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

A ruthenium(II) polypyridyl complex for direct imaging of DNA structure in living cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

A covalently linked phenanthridine-ruthenium(II) complex as a RNA probe.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Ruthenium polypyridyl peptide conjugates: membrane permeable probes for cellular imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Luminescent biological probes derived from ruthenium(II) estradiol polypyridine complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Multimodal cell imaging by ruthenium polypyridyl labelled cell penetrating peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Targeting a ruthenium complex to the nucleus with short peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Fluorescein redirects a ruthenium-octaarginine conjugate to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Ruthenium polypyridyl complexes that induce mitochondria-mediated apoptosis in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Identification of norharman as the cytotoxic compound produced by the sponge (Hymeniacidon perleve)-associated marine bacterium Pseudoalteromonas piscicida and its apoptotic effect on cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

β-Carboline kindling of the benzodiazepine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Inhibition of monoamine oxidase A by beta-carboline derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Effects of beta- and gamma-carboline derivatives of DNA topoisomerase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

New trends for metal complexes with anticancer activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Highly cytotoxic copper(II) complexes with modified paullone ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

A categorization of metal anticancer compounds based on their mode of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Bioorganometallic chemistry--from teaching paradigms to medicinal applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Synthesis, biochemical properties and molecular modelling studies of organometallic specific estrogen receptor modulators (SERMs), the ferrocifens and hydroxyferrocifens: evidence for an antiproliferative effect of hydroxyferrocifens on both hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Modification of the estrogenic properties of diphenols by the incorporation of ferrocene. Generation of antiproliferative effects in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Exploring biologically relevant chemical space with metal complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Iridium complex with antiangiogenic properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Nuclear permeable ruthenium(II) β-carboline complexes induce autophagy to antagonize mitochondrial-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Binding of 9-methylguanine to [cis-Ru(2,2'-bpy)2]2+: First X-ray structure of a cis-bis purine complex of ruthenium

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Ruthenium(II) complexes of 1,12-diazaperylene and their interactions with DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Methods to explore cellular uptake of ruthenium complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Mechanism of cellular uptake of a ruthenium polypyridyl complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Bistridentate ruthenium(II)polypyridyl-type complexes with microsecond 3MLCT state lifetimes: sensitizers for rod-like molecular arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Structure-activity relationships for cytotoxic ruthenium(II) arene complexes containing N,N-, N,O-, and O,O-chelating ligands.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Cellular uptake, cytotoxicity, and metabolic profiling of human cancer cells treated with ruthenium(II) polypyridyl complexes [Ru(bpy)2(N--N)]Cl2 with N--N=bpy, phen, dpq, dppz, and dppn

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Uptake of antitumor platinum(II)-complexes by cancer cells, assayed by inductively coupled plasma mass spectrometry (ICP-MS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

A cobaltocenium-peptide bioconjugate shows enhanced cellular uptake and directed nuclear delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Exploring the cellular accumulation of metal complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

A cytotoxic ruthenium tris(bipyridyl) complex that accumulates at plasma membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

The beta-carboline analog Mana-Hox causes mitotic aberration by interacting with DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

DNA binding of iron(II) complexes with 1,10-phenanthroline and 4,7-diphenyl-1,10-phenanthroline: salt effect, ligand substituent effect, base pair specificity and binding strength.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

EM011 activates a survivin-dependent apoptotic program in human non-small cell lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Apoptosis: a review of programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Emodin azide methyl anthraquinone derivative triggers mitochondrial-dependent cell apoptosis involving in caspase-8-mediated Bid cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Caspases in apoptosis and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

The heterocyclic ruthenium(III) complex KP1019 (FFC14A) causes DNA damage and oxidative stress in colorectal tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Dual regulation by apurinic/apyrimidinic endonuclease-1 inhibits gastric epithelial cell apoptosis during Helicobacter pylori infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Reactive oxygen species in cancer cells: live by the sword, die by the sword.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Synthesis and antitumor activity of 1,5-disubstituted 1,2,4-triazoles as cis-restricted combretastatin analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

A dinuclear copper(II) complex with adeninate bridge ligands and prominent DNA cleavage activity. Structural and spectroscopic characterization and magnetic properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Biological evaluation of non-steroidal anti-inflammatory drugs-cobalt(II) complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Steric protection of a photosensitizer in a N,N-bis[2-(2-pyridyl)ethyl]-2-phenylethylamine-copper(II) bowl that enhances red light-induced DNA cleavage activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Novel N-(3-carboxyl-9-benzyl-beta-carboline-1-yl)ethylamino acids: synthesis, anti-tumor evaluation, intercalating determination, 3D QSAR analysis and docking investigation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

Synthesis of novel beta-carbolines with efficient DNA-binding capacity and potent cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1DT10084J

21 January 2018

Identifiers

DOI

10.1039/C1DT10084J

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21804968%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference