(Q39504560)

12 September 2017

Non-redox-active lipoate derivates disrupt cancer cell mitochondrial metabolism and are potent anticancer agents in vivo (English)

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12 September 2017

Zuzana Zachar

1

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12 September 2017

James Marecek

2

1 reference

12 September 2017

Claudia Maturo

3

1 reference

12 September 2017

Sunita Gupta

4

1 reference

12 September 2017

Shawn D Stuart

5

1 reference

12 September 2017

Katy Howell

6

1 reference

12 September 2017

Alexandra Schauble

7

1 reference

12 September 2017

Joanna Lem

8

1 reference

12 September 2017

Arin Piramzadian

9

1 reference

12 September 2017

Sameer Karnik

10

1 reference

12 September 2017

King Lee

11

1 reference

12 September 2017

Robert Rodriguez

12

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12 September 2017

Robert Shorr

13

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12 September 2017

Paul M Bingham

14

1 reference

12 September 2017

19 July 2011

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Journal of Molecular Medicine

12 September 2017

1 reference

12 September 2017

89

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12 September 2017

11

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12 September 2017

1137-1148

1 reference

https://scigraph.springernature.com/pub.10.1007/s00109-011-0785-8

12 September 2017

0 references

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Deviant energetic metabolism of glycolytic cancer cells

21 January 2018

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The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

21 January 2018

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The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

21 January 2018

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Brick by brick: metabolism and tumor cell growth

21 January 2018

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

21 January 2018

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Regulation of cancer cell metabolism by hypoxia-inducible factor 1.

21 January 2018

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Regulation of cancer cell metabolism

21 January 2018

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Glycine cleavage system: reaction mechanism, physiological significance, and hyperglycinemia

21 January 2018

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The 2-oxo acid dehydrogenase complexes: recent advances

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-011-0785-8

Distinct regulatory properties of pyruvate dehydrogenase kinase and phosphatase isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0785-8

2-Oxo acid dehydrogenase complexes in redox regulation

21 January 2018

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Essential roles of lipoyl domains in the activated function and control of pyruvate dehydrogenase kinases and phosphatase isoform 1.

21 January 2018

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Pyruvate dehydrogenase kinase regulatory mechanisms and inhibition in treating diabetes, heart ischemia, and cancer

21 January 2018

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Pyruvate dehydrogenase and pyruvate dehydrogenase kinase expression in non small cell lung cancer and tumor-associated stroma

21 January 2018

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HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0785-8

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

21 January 2018

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Hypoxia, HIF1 and glucose metabolism in the solid tumour

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-011-0785-8

Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-011-0785-8

Induction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0785-8

Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0785-8

Apoptosis and non-apoptotic deaths in cancer development and treatment response

21 January 2018

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Multifaceted deaths orchestrated by mitochondria in neurones.

21 January 2018

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"Wages of fear": transient threefold decrease in intracellular ATP level imposes apoptosis.

21 January 2018

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The tumor suppressor function of mitochondria: translation into the clinics.

21 January 2018

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Targeting metabolic transformation for cancer therapy.

21 January 2018

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A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0785-8

Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0785-8

p53 mutations in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0785-8

Mitochondria consume energy and compromise cellular membrane potential by reversing ATP synthetase activity during focal ischemia in rats

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21769686

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Recent advances in mechanisms regulating glucose oxidation at the level of the pyruvate dehydrogenase complex by PDKs

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21769686

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Low-level c-myc amplification in human colonic carcinoma cell lines and tumors: a frequent, p53-independent mutation associated with improved outcome in a randomized multi-institutional trial

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21769686

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00109-011-0785-8

1 reference

12 September 2017

1 reference