(Q39521848)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21685937%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

title

SPARC functions as an anti-stress factor by inactivating p53 through Akt-mediated MDM2 phosphorylation to promote melanoma cell survival (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21685937%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

2

1 reference

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5 February 2020

Mélanie Tichet

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21685937%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Robert Ballotti

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21685937%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Sophie Tartare-Deckert

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21685937%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

author name string

N Fenouille

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21685937%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

G Zimniak

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21685937%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

P Abbe

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21685937%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

A Mallavialle

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21685937%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

S Rocchi

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21685937%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

J-P Ortonne

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21685937%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

M Deckert

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21685937%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

language of work or name

English

0 references

publication date

20 June 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21685937%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21685937%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

volume

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21685937%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

issue

49

1 reference

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5 February 2020

page(s)

4887-4900

1 reference

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https://scigraph.springernature.com/pub.10.1038/onc.2011.198

5 February 2020

exact match

0 references

cites work

SPARC: a matricellular regulator of tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Phosphorylation of HDM2 by Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Spleen tyrosine kinase functions as a tumor suppressor in melanoma cells by inducing senescence-like growth arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

SPARC regulates extracellular matrix organization through its modulation of integrin-linked kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Matricellular proteins: extracellular modulators of cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Transcriptional upregulation of SPARC, in response to c-Jun overexpression, contributes to increased motility and invasion of MCF7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

SPARC suppresses apoptosis of idiopathic pulmonary fibrosis fibroblasts through constitutive activation of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Specific activation of the p53 pathway by low dose actinomycin D: a new route to p53 based cyclotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Molecular pathway for cancer metastasis to bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Persistent activation of the Fyn/ERK kinase signaling axis mediates imatinib resistance in chronic myelogenous leukemia cells through upregulation of intracellular SPARC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

The p53/p21Cip1/ Waf1 pathway mediates the effects of SPARC on melanoma cell cycle progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Matricellular proteins produced by melanocytes and melanomas: in search for functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

HGF induces fibronectin matrix synthesis in melanoma cells through MAP kinase-dependent signaling pathway and induction of Egr-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Silencing of secreted protein acidic and rich in cysteine inhibits the growth of human melanoma cells with G arrest induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Reactive oxygen species are downstream mediators of p53-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Apoptosis: a link between cancer genetics and chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Proteomic identification of the wt-p53-regulated tumor cell secretome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

The complexity of p53 stabilization and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

The expression of the secreted protein acidic and rich in cysteine (SPARC) is associated with the neoplastic progression of human melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

The PTEN-AKT3 signaling cascade as a therapeutic target in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Keeping p53 in check: essential and synergistic functions of Mdm2 and Mdm4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

A novel form of Epstein-Barr virus latency in normal B cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

IFATS collection: Combinatorial peptides identify alpha5beta1 integrin as a receptor for the matricellular protein SPARC on adipose stromal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

SPARC functions as an inhibitor of adipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Akt enhances Mdm2-mediated ubiquitination and degradation of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Drosophila SPARC is a self-protective signal expressed by loser cells during cell competition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

SPARC represses E-cadherin and induces mesenchymal transition during melanoma development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Endothelial cell injury in vitro is associated with increased secretion of an Mr 43,000 glycoprotein ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Macrophage-derived SPARC bridges tumor cell-extracellular matrix interactions toward metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Mechanisms of p53-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Secreted protein acidic, rich in cysteine (SPARC), mediates cellular survival of gliomas through AKT activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Targeting SPARC expression decreases glioma cellular survival and invasion associated with reduced activities of FAK and ILK kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Osteonectin downregulates E-cadherin, induces osteopontin and focal adhesion kinase activity stimulating an invasive melanoma phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Apoptosis and melanoma chemoresistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

A novel interaction between procaspase 8 and SPARC enhances apoptosis and potentiates chemotherapy sensitivity in colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

BRAF as a potential therapeutic target in melanoma and other malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

21 January 2018

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

The copper binding domain of SPARC mediates cell survival in vitro via interaction with integrin beta1 and activation of integrin-linked kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

SPARC (secreted protein acidic and rich in cysteine) induces apoptosis in ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Suppression of SPARC expression by antisense RNA abrogates the tumorigenicity of human melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Osteonectin expression correlates with clinical outcome in thin cutaneous malignant melanomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

SPARC and thrombospondin genes are repressed by the c-jun oncogene in rat embryo fibroblasts.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Mechanisms of p53-dependent apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198

Mutation and expression of the p53 gene in malignant melanoma cell lines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.198