(Q39523760)

12 September 2017

title

SIRT1 RNAi knockdown induces apoptosis and senescence, inhibits invasion and enhances chemosensitivity in pancreatic cancer cells (English)

1 reference

12 September 2017

1 reference

1 reference

1

G. Zhao

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21677689

4 December 2024

author name string

J-G Zhang

3

1 reference

12 September 2017

S-C Deng

7

1 reference

12 September 2017

G-B Wang

12

1 reference

12 September 2017

C-Y Wang

13

1 reference

12 September 2017

J. Cui

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21677689

4 December 2024

Q. Qin

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21677689

4 December 2024

Q. Chen

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21677689

4 December 2024

T. Yin

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21677689

4 December 2024

Y. Liu

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21677689

4 December 2024

L. Liu

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21677689

4 December 2024

B. Wang

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21677689

4 December 2024

K. Tian

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21677689

4 December 2024

language of work or name

1 reference

16 June 2011

1 reference

full work available at URL

12 September 2017

https://www.nature.com/articles/gt201181.pdf

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21677689

https://www.nature.com/articles/gt201181.pdf

4 December 2024

1 reference

https://api.crossref.org/works/10.1038/GT.2011.81

https://www.nature.com/articles/gt201181

4 December 2024

1 reference

https://api.crossref.org/works/10.1038/GT.2011.81

4 December 2024

1 reference

12 September 2017

volume

18

1 reference

12 September 2017

issue

9

1 reference

12 September 2017

page(s)

920-928

1 reference

12 September 2017

cites work

Cancer statistics, 2008

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Invasion and metastasis in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Histone deacetylases and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Sirtuins: critical regulators at the crossroads between cancer and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

The Sir 2 family of protein deacetylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Transcriptional regulation of neuronal genes and its effect on neural functions: NAD-dependent histone deacetylase SIRT1 (Sir2alpha).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Sirtuins as potential targets for metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Mammalian SIRT1 represses forkhead transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Sirtuins in mammals: insights into their biological function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

The fundamental role of epigenetic events in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

SIRT1 is significantly elevated in mouse and human prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Function of the SIRT1 protein deacetylase in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Hyaluronan-mediated CD44 interaction with p300 and SIRT1 regulates beta-catenin signaling and NFkappaB-specific transcription activity leading to MDR1 and Bcl-xL gene expression and chemoresistance in breast tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

The significances of lymph node micrometastasis and its correlation with E-cadherin expression in pT1-T3N0 gastric adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Control of multidrug resistance gene mdr1 and cancer resistance to chemotherapy by the longevity gene sirt1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

SIRT1: tumor promoter or tumor suppressor?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

SirT1 is an inhibitor of proliferation and tumor formation in colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Role of p53 in the anti-proliferative effects of Sirt1 inhibition in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Overexpression of neuropilin-1 promotes constitutive MAPK signalling and chemoresistance in pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

High histone deacetylase 7 (HDAC7) expression is significantly associated with adenocarcinomas of the pancreas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

SIRT1 expression is associated with poor prognosis of diffuse large B-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Expression of DBC1 and SIRT1 is associated with poor prognosis for breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Expression of DBC1 and SIRT1 is associated with poor prognosis of gastric carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Expression and prognostic significance of SIRT1 in ovarian epithelial tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Role of sirtuin histone deacetylase SIRT1 in prostate cancer. A target for prostate cancer management via its inhibition?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Phosphorylation of forkhead transcription factors by erythropoietin and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Double identity for proteins of the Bcl-2 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Bax-inhibiting peptide protects cells from polyglutamine toxicity caused by Ku70 acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Caspase-3 activation downstream from reactive oxygen species in heat-induced apoptosis of pancreatic carcinoma cells carrying a mutant p53 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Autocrine motility factor signaling enhances pancreatic cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

Involvement of mitochondria and caspase pathways in N-demethyl-clarithromycin-induced apoptosis in human cervical cancer HeLa cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

inferred from DOI database lookup

7 January 2021

based on heuristic

Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.81

inferred from DOI database lookup

7 January 2021

based on heuristic

E-cadherin transcriptional down-regulation by epigenetic and microRNA-200 family alterations is related to mesenchymal and drug-resistant phenotypes in human breast cancer cells

https://api.crossref.org/works/10.1038/GT.2011.81

22

1 reference

4 December 2024

Identifiers

DOI

10.1038/GT.2011.81

1 reference

Dimensions Publication ID

12 September 2017

1004192321

0 references

Fatcat ID

release_ut3cggeanrhapkbkkyayf7ai7a

0 references

1 reference