(Q39529355)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21647879%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

title

Reactivation of p53 mutants by prima-1 [corrected] in thyroid cancer cells (English)

1 reference

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3 February 2020

1 reference

3

1 reference

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3 February 2020

Fiorenza Gianì

7

1 reference

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3 February 2020

author name string

Rosa Linda Messina

1

1 reference

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3 February 2020

Mariangela Sanfilippo

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21647879%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Giuseppe Pandini

4

1 reference

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3 February 2020

Paolo Vigneri

5

1 reference

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3 February 2020

Maria Luisa Nicolosi

6

1 reference

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3 February 2020

Riccardo Vigneri

8

1 reference

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3 February 2020

Francesco Frasca

9

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3 February 2020

language of work or name

English

0 references

publication date

14 September 2011

1 reference

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International Journal of Cancer

3 February 2020

published in

1 reference

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3 February 2020

volume

130

1 reference

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3 February 2020

issue

10

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3 February 2020

page(s)

2259-2270

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21647879%20AND%20SRC:MED&resulttype=core&format=json

Annual report to the nation on the status of cancer (1973 through 1998), featuring cancers with recent increasing trends

3 February 2020

cites work

1 reference

Descriptive epidemiology of thyroid carcinoma in Carinthia, Austria: 1984-2001. Histopathologic features and tumor classification of 734 cases under elevated general iodination of table salt since 1990: population-based age-stratified analysis on th

21 January 2018

1 reference

BRAF mutation in papillary thyroid cancer: pathogenic role, molecular bases, and clinical implications

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Gene methylation in thyroid tumorigenesis

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P53 mutations in thyroid carcinoma: tidings from an old foe.

21 January 2018

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High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas

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Targeting p53 by PTD-mediated transduction

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Effects of p53-expressing adenovirus on the chemosensitivity and differentiation of anaplastic thyroid cancer cells

21 January 2018

1 reference

A histone deacetylase inhibitor enhances killing of undifferentiated thyroid carcinoma cells by p53 gene therapy

21 January 2018

1 reference

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.

21 January 2018

1 reference

A novel p53 rescue compound induces p53-dependent growth arrest and sensitises glioma cells to Apo2L/TRAIL-induced apoptosis

21 January 2018

1 reference

Strategies for therapeutic targeting of the p53 pathway in cancer.

21 January 2018

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Adenoviral vectors for gene therapy

21 January 2018

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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

21 January 2018

1 reference

Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

21 January 2018

1 reference

Characterization of the p53-rescue drug CP-31398 in vitro and in living cells.

21 January 2018

1 reference

Effects of PRIMA-1 on chronic lymphocytic leukaemia cells with and without hemizygous p53 deletion.

21 January 2018

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PRIMA-1 synergizes with adriamycin to induce cell death in non-small cell lung cancer cells.

21 January 2018

1 reference

Proteomic identification of heat shock protein 90 as a candidate target for p53 mutation reactivation by PRIMA-1 in breast cancer cells

21 January 2018

1 reference

PRIMA-1 reactivates mutant p53 by covalent binding to the core domain

21 January 2018

1 reference

Mutant p53 reactivation by PRIMA-1MET induces multiple signaling pathways converging on apoptosis.

21 January 2018

1 reference

Mutational analysis of p73 and p53 in human cancer cell lines.

21 January 2018

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PRIMA-1(MET)/APR-246 targets mutant forms of p53 family members p63 and p73.

21 January 2018

1 reference

Small-molecule modulators of p53 family signaling and antitumor effects in p53-deficient human colon tumor xenografts.

21 January 2018

1 reference

Mutant p53-dependent growth suppression distinguishes PRIMA-1 from known anticancer drugs: a statistical analysis of information in the National Cancer Institute database.

21 January 2018

1 reference

Effects of exogenous p53 transduction in thyroid tumor cells with different p53 status

21 January 2018

1 reference

Failure of wild-type p53 gene therapy in human cancer cells expressing a mutant p53 protein.

21 January 2018

1 reference

p53 family proteins in thyroid cancer.

21 January 2018

1 reference

Physical interaction with human tumor-derived p53 mutants inhibits p63 activities.

21 January 2018

1 reference

TAp73 alpha increases p53 tumor suppressor activity in thyroid cancer cells via the inhibition of Mdm2-mediated degradation

21 January 2018

1 reference

21 January 2018

1 reference

Histone deacetylase inhibitors promote apoptosis and differential cell cycle arrest in anaplastic thyroid cancer cells

21 January 2018

1 reference

Increasing the effectiveness of radioactive iodine therapy in the treatment of thyroid cancer using Trichostatin A, a histone deacetylase inhibitor

21 January 2018

1 reference

In thyroid cancer cell lines expression of periostin gene is controlled by p73 and is not related to epigenetic marks of active transcription.

21 January 2018

1 reference

PRIMA-1(MET) synergizes with cisplatin to induce tumor cell apoptosis.

21 January 2018

1 reference