(Q39538459)

12 September 2017

The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis (English)

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12 September 2017

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1

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19

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12 September 2017

Rory Stark

5

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James Hadfield

James Hadfield

17

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Gina M DeNicola

Gina M Denicola

14

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Scott K Lyons

Scott K Lyons

20

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Andy G. Lynch

Andy Lynch

2

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Madhu Basetti

Basetti Madhu

9

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David E. Neal

David E Neal

25

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author name string

Antonio Ramos-Montoya

3

1 reference

12 September 2017

Joan Boren

4

1 reference

12 September 2017

Ladan Fazli

6

1 reference

12 September 2017

Anne Warren

7

1 reference

12 September 2017

Helen Scott

8

1 reference

12 September 2017

Naomi Sharma

10

1 reference

12 September 2017

Helene Bon

11

1 reference

12 September 2017

Vinny Zecchini

12

1 reference

12 September 2017

Donna-Michelle Smith

13

1 reference

12 September 2017

Nik Mathews

15

1 reference

12 September 2017

Michelle Osborne

16

1 reference

12 September 2017

Stewart Macarthur

18

1 reference

12 September 2017

Kevin M Brindle

21

1 reference

12 September 2017

John Griffiths

22

1 reference

12 September 2017

Martin E Gleave

23

1 reference

12 September 2017

Paul S Rennie

24

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12 September 2017

Ian G Mills

26

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12 September 2017

language of work or name

English

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publication date

20 May 2011

1 reference

12 September 2017

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12 September 2017

30

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12 September 2017

2719-2733

1 reference

12 September 2017

13

1 reference

describes a project that uses

12 September 2017

Cytoscape

1 reference

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

inferred from PubMed Central ID database lookup

cites work

Evidence for an alternative glycolytic pathway in rapidly proliferating cells

1 reference

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An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression

13 September 2017

1 reference

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The glucose-responsive transcription factor ChREBP contributes to glucose-dependent anabolic synthesis and cell proliferation

13 September 2017

1 reference

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Integrated expression profiling and ChIP-seq analyses of the growth inhibition response program of the androgen receptor

13 September 2017

1 reference

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Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer

13 September 2017

1 reference

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

13 September 2017

1 reference

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AMP-activated protein kinase promotes human prostate cancer cell growth and survival

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Treatment-dependent androgen receptor mutations in prostate cancer exploit multiple mechanisms to evade therapy

13 September 2017

1 reference

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Development of a second-generation antiandrogen for treatment of advanced prostate cancer

13 September 2017

1 reference

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Fatty acid synthase: a metabolic enzyme and candidate oncogene in prostate cancer

13 September 2017

1 reference

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Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters

13 September 2017

1 reference

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Genome-scale validation of deep-sequencing libraries

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Genomic androgen receptor-occupied regions with different functions, defined by histone acetylation, coregulators and transcriptional capacity

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Model-based analysis of ChIP-Seq (MACS)

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Species-specific transcription in mice carrying human chromosome 21

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Mapping short DNA sequencing reads and calling variants using mapping quality scores

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Hypothalamic CaMKK2 contributes to the regulation of energy balance

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

AMPK phosphorylation of raptor mediates a metabolic checkpoint

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

High-throughput tissue extraction protocol for NMR- and MS-based metabolomics

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Cell- and gene-specific regulation of primary target genes by the androgen receptor

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

beadarray: R classes and methods for Illumina bead-based data.

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

A framework for collaborative analysis of ENCODE data: making large-scale analyses biologist-friendly

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Identification of novel androgen receptor target genes in prostate cancer

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Androgen-regulated genes differentially modulated by the androgen receptor coactivator L-dopa decarboxylase in human prostate cancer cells

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Genome-wide mapping of in vivo protein-DNA interactions

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

High-resolution profiling of histone methylations in the human genome

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Identification of novel androgen response genes in prostate cancer cells by coupling chromatin immunoprecipitation and genomic microarray analysis

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Pathway analysis of kidney cancer using proteomics and metabolic profiling

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Ubiquitin E3 ligase WWP1 as an oncogenic factor in human prostate cancer

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Genome-wide analysis of estrogen receptor binding sites

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Identification of novel steroid target genes through the combination of bioinformatics and functional analysis of hormone response elements

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

NestedMICA: sensitive inference of over-represented motifs in nucleic acid sequence

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Identification and validation of novel androgen-regulated genes in prostate cancer

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

ONCOMINE: a cancer microarray database and integrated data-mining platform

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

MEK5 overexpression is associated with metastatic prostate cancer, and stimulates proliferation, MMP-9 expression and invasion

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic disease

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

STO-609, a specific inhibitor of the Ca(2+)/calmodulin-dependent protein kinase kinase

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

P504S: a new molecular marker for the detection of prostate carcinoma

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

In vivo amplification of the androgen receptor gene and progression of human prostate cancer

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

The value of prior knowledge in discovering motifs with MEME.

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

A consensus DNA-binding site for the androgen receptor

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

CaM kinase kinase beta-mediated activation of the growth regulatory kinase AMPK is required for androgen-dependent migration of prostate cancer cells

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Androgen receptor amplification is reflected in the transcriptional responses of Vertebral-Cancer of the Prostate cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Inactivation of AMPK alters gene expression and promotes growth of prostate cancer cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

In vivo knockdown of the androgen receptor results in growth inhibition and regression of well-established, castration-resistant prostate tumors.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Development of a small-molecule serum- and glucocorticoid-regulated kinase-1 antagonist and its evaluation as a prostate cancer therapeutic.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Androgen receptor and invasion in prostate cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

New androgen receptor genomic targets show an interaction with the ETS1 transcription factor.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Androgen receptor-mediated repression of novel target genes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Androgens induce prostate cancer cell proliferation through mammalian target of rapamycin activation and post-transcriptional increases in cyclin D proteins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Identification and functional analysis of consensus androgen response elements in human prostate cancer cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Identification of an androgen response element in intron 8 of the sterol regulatory element-binding protein cleavage-activating protein gene allowing direct regulation by the androgen receptor

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

BASH: a tool for managing BeadArray spatial artefacts

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Androgen receptor down regulation by small interference RNA induces cell growth inhibition in androgen sensitive as well as in androgen independent prostate cancer cells.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Discovery of BMS-641988, a novel and potent inhibitor of androgen receptor signaling for the treatment of prostate cancer

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

The stable isotope-based dynamic metabolic profile of butyrate-induced HT29 cell differentiation

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Androgens stimulate lipogenic gene expression in prostate cancer cells by activation of the sterol regulatory element-binding protein cleavage activating protein/sterol regulatory element-binding protein pathway

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Multiple G1 regulatory elements control the androgen-dependent proliferation of prostatic carcinoma cells.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155295

Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression

21 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.158

Alpha-methylacyl coenzyme A racemase as a marker for prostate cancer

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21602788

12 December 2020

inferred from PubMed ID database lookup

Rat liver phosphofructokinase. Purification and characterization of its reaction mechanism

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21602788

12 December 2020

inferred from PubMed ID database lookup

Zinc inhibition of mitochondrial aconitase and its importance in citrate metabolism of prostate epithelial cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21602788

12 December 2020

inferred from PubMed ID database lookup

Using galaxy to perform large-scale interactive data analyses

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.158

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/EMBOJ.2011.158

1 reference

12 September 2017

1 reference

12 September 2017

1 reference