(Q33421665)

26 July 2017

title

Fatty acid synthase: a metabolic enzyme and candidate oncogene in prostate cancer (English)

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26 July 2017

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1 reference

Stephen Finn

21

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Andrew L. Kung

object named as

Andrew L Kung

13

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Lorelei A. Mucci

16

object named as

Lorelei Mucci

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26 July 2017

22

Massimo Loda

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26 July 2017

19

Meir Stampfer

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26 July 2017

20

William C Hahn

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26 July 2017

8

Chiara Grisanzio

1 reference

26 July 2017

14

Phillip G Febbo

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26 July 2017

18

Sabina Signoretti

1 reference

26 July 2017

Toshiro Migita

1

1 reference

26 July 2017

Stacey Ruiz

2

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26 July 2017

Alessandro Fornari

3

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26 July 2017

Michelangelo Fiorentino

4

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26 July 2017

Carmen Priolo

5

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26 July 2017

Giorgia Zadra

6

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26 July 2017

Fumika Inazuka

7

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26 July 2017

Emanuele Palescandolo

9

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26 July 2017

Eyoung Shin

10

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26 July 2017

Christopher Fiore

11

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26 July 2017

Wanling Xie

12

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26 July 2017

Aravind Subramanian

15

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26 July 2017

Jing Ma

17

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26 July 2017

language of work or name

English

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publication date

24 March 2009

1 reference

Journal of the National Cancer Institute

26 July 2017

published in

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26 July 2017

volume

101

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26 July 2017

issue

7

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26 July 2017

page(s)

519-532

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Vitamins E and C in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial

26 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Prediagnostic body-mass index, plasma C-peptide concentration, and prostate cancer-specific mortality in men with prostate cancer: a long-term survival analysis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

The crystal structure of a mammalian fatty acid synthase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Fatty acid synthase inhibition with Orlistat promotes apoptosis and reduces cell growth and lymph node metastasis in a mouse melanoma model

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Synthesis of novel beta-lactone inhibitors of fatty acid synthase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

A new mechanism of drug resistance in breast cancer cells: fatty acid synthase overexpression-mediated palmitate overproduction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Overexpression of fatty acid synthase gene activates HER1/HER2 tyrosine kinase receptors in human breast epithelial cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Novel targeted pro-apoptotic agents for the treatment of prostate cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

The apoptosome: signalling platform of cell death

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Prospective study of adiposity and weight change in relation to prostate cancer incidence and mortality

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Obesity, adipokines, and prostate cancer (review).

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Role of diet in prostate cancer development and progression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

ATP citrate lyase inhibition can suppress tumor cell growth

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

High-level expression of fatty acid synthase in human prostate cancer tissues is linked to activation and nuclear localization of Akt/PKB.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

20-year outcomes following conservative management of clinically localized prostate cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Androgen-induced differentiation and tumorigenicity of human prostate epithelial cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Molecular genetics of human prostate cancer.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Fatty acid synthase: a metabolic oncogene in prostate cancer?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Fatty acid synthase expression defines distinct molecular signatures in prostate cancer.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Pharmacological inhibition of fatty acid synthase activity produces both cytostatic and cytotoxic effects modulated by p53.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Mitochondrial control of cell death

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Synthesis and antitumor activity of an inhibitor of fatty acid synthase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Body size and prostate cancer: a 20-year follow-up study among 135006 Swedish construction workers

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Fatty acid synthesis: a potential selective target for antineoplastic therapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

A randomized trial of aspirin and beta-carotene among U.S. physicians

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Prospective study of alcohol consumption and risk of coronary disease in men.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Fatty acid synthase is expressed mainly in adult hormone-sensitive cells or cells with high lipid metabolism and in proliferating fetal cells

28 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJP030

Increased expression of fatty acid synthase (OA-519) in ovarian neoplasms predicts shorter survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJP030

Orlistat is a novel inhibitor of fatty acid synthase with antitumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJP030

Multiple newly identified loci associated with prostate cancer susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJP030

Height, body mass index, and prostate cancer: a follow-up of 950000 Norwegian men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJP030

Body mass index, weight change, and risk of prostate cancer in the Cancer Prevention Study II Nutrition Cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJP030

Inhibition of fatty acid synthase activity in prostate cancer cells by dutasteride

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJP030

Fatty acid synthase gene is up-regulated by hypoxia via activation of Akt and sterol regulatory element binding protein-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJP030

Fatty acid synthase drives the synthesis of phospholipids partitioning into detergent-resistant membrane microdomains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJP030

The isopeptidase USP2a protects human prostate cancer from apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJP030

Mechanisms of apoptosis resistance and treatment strategies to overcome them in hormone-refractory prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJP030

Discovery of GSK837149A, an inhibitor of human fatty acid synthase targeting the beta-ketoacyl reductase reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJP030

1-11C-acetate as a PET radiopharmaceutical for imaging fatty acid synthase expression in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJP030

RNA interference-mediated silencing of the fatty acid synthase gene attenuates growth and induces morphological changes and apoptosis of LNCaP prostate cancer cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Apoptosis of androgen-independent prostate cell line induced by inhibition of fatty acid synthesis

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664091

Fatty acid synthase gene overexpression and copy number gain in prostate adenocarcinoma☆

31 October 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJP030

Obesity, Diabetes, and Risk of Prostate Cancer: Results from the Prostate Cancer Prevention Trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJP030

Metabolism of neoplastic tissue. IV. A study of lipid synthesis in neoplastic tissue slices in vitro

21 January 2018

1 reference

12 December 2020

Expression of fatty acid synthase as a prognostic indicator in soft tissue sarcomas

1 reference

12 December 2020

Fatty acid synthase (FAS) is a marker of increased risk of recurrence in lung carcinoma

1 reference

12 December 2020

Gastrointestinal stromal tumours overexpress fatty acid synthase

1 reference

12 December 2020

Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells

1 reference

12 December 2020

Fatty acid synthase (FAS): a target for cytotoxic antimetabolites in HL60 promyelocytic leukemia cells

1 reference

12 December 2020

Expression of fatty acid synthase (FAS) as a predictor of recurrence in stage I breast carcinoma patients

1 reference

12 December 2020

Immunohistochemical detection of a fatty acid synthase (OA-519) as a predictor of progression of prostate cancer

1 reference

12 December 2020

Association of smoking, body mass, and physical activity with risk of prostate cancer in the Iowa 65+ Rural Health Study (United States)

1 reference

12 December 2020

Pharmacological inhibitors of mammalian fatty acid synthase suppress DNA replication and induce apoptosis in tumor cell lines

1 reference

12 December 2020

Identifiers

DOI

10.1093/JNCI/DJP030

1 reference

26 July 2017

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26 July 2017

1 reference