(Q39541493)

English

Squamous cell carcinoma antigen 1 promotes caspase-8-mediated apoptosis in response to endoplasmic reticulum stress while inhibiting necrosis induced by lysosomal injury

scientific article published on 16 May 2011

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Squamous cell carcinoma antigen 1 promotes caspase-8-mediated apoptosis in response to endoplasmic reticulum stress while inhibiting necrosis induced by lysosomal injury (English)

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

endoplasmic reticulum

0 references

squamous cell carcinoma

1 reference

based on heuristic

inferred from title

author name string

Erica Ullman

1

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Ji-An Pan

2

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Wei-Xing Zong

3

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

language of work or name

0 references

publication date

16 May 2011

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

31

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

14

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

2902-2919

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Inhibition of protein degradation induces apoptosis through a microtubule-associated protein 1 light chain 3-mediated activation of caspase-8 at intracellular membranes

1 reference

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Elevated expression of squamous cell carcinoma antigen (SCCA) is associated with human breast carcinoma

1 reference

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Characterization of cytoplasmic caspase-2 activation by induced proximity.

1 reference

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Proteasome inhibitors in the treatment of multiple myeloma

1 reference

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Therapeutic strategies within the ubiquitin proteasome system.

1 reference

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Lysosomes as "suicide bags" in cell death: myth or reality?

1 reference

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Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling

1 reference

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1 reference

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Autophagy promotes necrosis in apoptosis-deficient cells in response to ER stress

1 reference

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An intracellular serpin regulates necrosis by inhibiting the induction and sequelae of lysosomal injury

1 reference

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ER stress triggers apoptosis by activating BH3-only protein Bim

1 reference

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p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

1 reference

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13 September 2017

Autophagy is activated for cell survival after endoplasmic reticulum stress

1 reference

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13 September 2017

Endoplasmic reticulum stress triggers autophagy

1 reference

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1 reference

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The apoptosome activates caspase-9 by dimerization

1 reference

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Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression

1 reference

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Serpin squamous cell carcinoma antigen inhibits UV-induced apoptosis via suppression of c-JUN NH2-terminal kinase

1 reference

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Functional coupling of p38-induced up-regulation of BiP and activation of RNA-dependent protein kinase-like endoplasmic reticulum kinase to drug resistance of dormant carcinoma cells.

1 reference

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Lysosomes as targets for cancer therapy

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The amplified mouse squamous cell carcinoma antigen gene locus contains a serpin (Serpinb3b) that inhibits both papain-like cysteine and trypsin-like serine proteinases

1 reference

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The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress

1 reference

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The Bcl-2 family: roles in cell survival and oncogenesis.

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Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway

1 reference

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Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis

1 reference

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Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion

1 reference

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A unified model for apical caspase activation

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Bax and Bak independently promote cytochrome C release from mitochondria

1 reference

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Dimer formation drives the activation of the cell death protease caspase 9

1 reference

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BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

1 reference

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

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Structure of a serpin-protease complex shows inhibition by deformation

1 reference

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Circulating serpin tumor markers SCCA1 and SCCA2 are not actively secreted but reside in the cytosol of squamous carcinoma cells

1 reference

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Simple modifications of the serpin reactive site loop convert SCCA2 into a cysteine proteinase inhibitor: a critical role for the P3' proline in facilitating RSL cleavage

1 reference

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Inhibition of apoptosis in human tumour cells by the tumour-associated serpin, SCC antigen-1.

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

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Caspase-9 and APAF-1 form an active holoenzyme

1 reference

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Caspase activation: the induced-proximity model

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Apoptosis control by death and decoy receptors

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Death receptors: signaling and modulation

1 reference

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

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1 reference

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Squamous cell carcinoma antigen is a new member of the serine protease inhibitors

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Proteasome inhibitors in cancer therapy

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https://pubmed.ncbi.nlm.nih.gov/21576355

12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21576355

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Identifiers

10.1128/MCB.05452-11

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

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