(Q39560130)

13 September 2017

title

DNMT3B gene amplification predicts resistance to DNA demethylating drugs (English)

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Laia Simó-Riudalbas

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publication date

11 April 2011

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Genes, Chromosomes and Cancer

13 September 2017

published in

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volume

50

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issue

7

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13 September 2017

page(s)

527-534

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Gene amplification in cancer

13 September 2017

cites work

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Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma

21 January 2018

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An essential role for DNA methyltransferase DNMT3B in cancer cell survival

21 January 2018

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Aberrant epigenetic landscape in cancer: how cellular identity goes awry

21 January 2018

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A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation

21 January 2018

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The history of cancer epigenetics

21 January 2018

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A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors

21 January 2018

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Hypomethylating agents and other novel strategies in myelodysplastic syndromes

21 January 2018

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A novel DNMT3B splice variant expressed in tumor and pluripotent cells modulates genomic DNA methylation patterns and displays altered DNA binding.

21 January 2018

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An inactivating mutation in HDAC2 leads to dysregulation of apoptosis mediated by APAF1.

21 January 2018

1 reference

Function of a human cyclin gene as an oncogene

21 January 2018

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Outcome of patients with myelodysplastic syndrome after failure of decitabine therapy

21 January 2018

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Molecular enzymology of mammalian DNA methyltransferases

21 January 2018

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Cellular differentiation, cytidine analogs and DNA methylation

21 January 2018

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The epigenomics of cancer

21 January 2018

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Nanaomycin A Selectively Inhibits DNMT3B and Reactivates Silenced Tumor Suppressor Genes in Human Cancer Cells

21 January 2018

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DNMT3A Mutations in Acute Myeloid Leukemia

21 January 2018

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Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements

21 January 2018

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Suppression of intestinal neoplasia by deletion of Dnmt3b

21 January 2018

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Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing

21 January 2018

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The RNA-binding protein HuR regulates DNA methylation through stabilization of DNMT3b mRNA.

21 January 2018

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Advances in the treatment of acute myeloid leukemia: from chromosomal aberrations to biologically targeted therapy

21 January 2018

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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

21 January 2018

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DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

21 January 2018

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Human concentrative nucleoside transporter 1-mediated uptake of 5-azacytidine enhances DNA demethylation

21 January 2018

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DNA methylation, methyltransferases, and cancer

21 January 2018

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The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors

21 January 2018

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Cancer epigenetics reaches mainstream oncology

21 January 2018

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DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines

21 January 2018

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A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition

21 January 2018

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Solving the Dnmt2 enigma.

21 January 2018

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DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis.

21 January 2018

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DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromes

21 January 2018

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Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

21 January 2018

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DNA methyltransferase 3b contributes to oncogenic transformation induced by SV40T antigen and activated Ras.

21 January 2018

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Targeting DNA methylation for epigenetic therapy

21 January 2018

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Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplastic progression

21 January 2018

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DNMT3b polymorphism and hereditary nonpolyposis colorectal cancer age of onset

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1002/GCC.20877

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13 September 2017

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