(Q39581477)

13 September 2017

title

PKCδ regulates Mdm2 independently of p53 in the apoptotic response to DNA damage (English)

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13 September 2017

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Hoi Chin Hew

1

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13 September 2017

Hanshao Liu

series ordinal

2

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13 September 2017

Yoshio Miki

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3

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13 September 2017

Kiyotsugu Yoshida

series ordinal

4

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13 September 2017

publication date

3 March 2011

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13 September 2017

published in

Molecular Carcinogenesis

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13 September 2017

volume

50

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13 September 2017

issue

9

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13 September 2017

page(s)

719-731

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Protein kinase Cdelta supports survival of MDA-MB-231 breast cancer cells by suppressing the ERK1/2 pathway

13 September 2017

cites work

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PKC Delta (PKCdelta) promotes tumoral progression of human ductal pancreatic cancer

21 January 2018

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Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf.

21 January 2018

1 reference

PKCdelta survival signaling in cells containing an activated p21Ras protein requires PDK1.

21 January 2018

1 reference

The enigmatic protein kinase Cdelta: complex roles in cell proliferation and survival

21 January 2018

1 reference

Distinctive activation mechanisms and functions for protein kinase Cdelta

21 January 2018

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PKCdelta signaling: mechanisms of DNA damage response and apoptosis

21 January 2018

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Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis

21 January 2018

1 reference

Caspase-3-dependent protein kinase C delta activity is required for the progression of Ginsenoside-Rh2-induced apoptosis in SK-HEP-1 cells

21 January 2018

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Activation of protein kinase C delta by the c-Abl tyrosine kinase in response to ionizing radiation

21 January 2018

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Interaction between protein kinase C delta and the c-Abl tyrosine kinase in the cellular response to oxidative stress

21 January 2018

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Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosis

21 January 2018

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Protein kinase Cdelta is responsible for constitutive and DNA damage-induced phosphorylation of Rad9

21 January 2018

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Protein kinase C delta regulates Ser46 phosphorylation of p53 tumor suppressor in the apoptotic response to DNA damage

21 January 2018

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Protein kinase C delta induces transcription of the TP53 tumor suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damage

21 January 2018

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Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line

21 January 2018

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Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

21 January 2018

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Regulation of p53 stability by Mdm2

21 January 2018

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Mdm2 promotes the rapid degradation of p53

21 January 2018

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Mdm2 association with p53 targets its ubiquitination

21 January 2018

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Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

21 January 2018

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Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

21 January 2018

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The p53-mdm-2 autoregulatory feedback loop

21 January 2018

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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

21 January 2018

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Intrinsic ubiquitination activity of PCAF controls the stability of the oncoprotein Hdm2

21 January 2018

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A non-proteolytic role for ubiquitin in Tat-mediated transactivation of the HIV-1 promoter

21 January 2018

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Functional interaction between SHPTP1 and the Lyn tyrosine kinase in the apoptotic response to DNA damage

21 January 2018

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Murine double minute 2: p53-independent roads lead to genome instability or death

21 January 2018

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Critical role for Daxx in regulating Mdm2

21 January 2018

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Regulatory cross-talk between lysine acetylation and ubiquitination: role in the control of protein stability

21 January 2018

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DNA-damaging aryl hydrocarbons induce Mdm2 expression via p53-independent post-transcriptional mechanisms

21 January 2018

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Mdm2 exerts pro-apoptotic activities by antagonizing insulin-like growth factor-I-mediated survival

21 January 2018

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Mdm2-dependent ubiquitination and degradation of the insulin-like growth factor 1 receptor

21 January 2018

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The mdm2 proto-oncogene sensitizes human medullary thyroid carcinoma cells to ionizing radiation

21 January 2018

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The MDM2 oncoprotein promotes apoptosis in p53-deficient human medullary thyroid carcinoma cells

21 January 2018

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MDM2 gene amplification and expression in non-small-cell lung cancer: immunohistochemical expression of its protein is a favourable prognostic marker in patients without p53 protein accumulation

21 January 2018

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PKC-δ is an apoptotic lamin kinase

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/MC.20748

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13 September 2017

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